WordNet

a substance that opposes or blocks the action of acetylcholine (同)anticholinergic_drug
inhibiting or blocking the action of acetylcholine at a receptor site; "anticholinergic drugs"
use recreational drugs (同)do drugs
administer a drug to; "They drugged the kidnapped tourist" (同)dose
a substance that is used as a medicine or narcotic

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Khnychenko LK, Okunevich IV, Losev NA, Sapronov NS, Yakovleva EE.SourceInstitute of Experimental Medicine, North-Western Division of the Russian Academy of Medical Sciences, St. Petersburg, Russia. Ludmila.Konst83@ mail.ru
Bulletin of experimental biology and medicine.Bull Exp Biol Med.2012 Aug;153(4):487-9.
We have found that N-cholinolytic drug benzohexonium produces a hypolipidemic effect: it reduces dyslipoproteinemia, fatty infiltration of the liver, and risk of atherosclerotic lesions.
PMID 22977852

Sildenafil, a phosphodiesterase type 5 inhibitor, enhances the antidepressant activity of amitriptyline but not desipramine, in the forced swim test in mice.

Socała K, Nieoczym D, Wyska E, Poleszak E, Wlaź P.SourceDepartment of Animal Physiology, Institute of Biology and Biochemistry, Maria Curie-Skłodowska University, Akademicka 19, 20-033 Lublin, Poland.
Journal of neural transmission (Vienna, Austria : 1996).J Neural Transm.2012 Jun;119(6):645-52. doi: 10.1007/s00702-011-0756-9. Epub 2012 Jan 4.
The cholinergic theory of depression highlights the involvement of muscarinic acetylcholine receptors in the neurobiology of mood disorders. The present study was designed to investigate the effect of sildenafil, a phosphodiesterase type 5 inhibitor which exhibits cholinomimetic properties, alone an
PMID 22215207

小林龍男 [他],村山智,久我哲郎,石川稔生,石山淳一,久野恒一,竹本道子,コバヤシタツオ,ムラヤマサトシ,クガテツロウ,イシカワトシオ,イシヤマジュンイチ,クノコウイチ,タケモトミチコ,KOBAYASHI TATSUO,MURAYAMA SATOSHI,KUGA TETSURO,ISHIKAWA TOSHIO,ISHIYAMA JUN-ICEI,KUNO KOICHI,TAKEMOTO MICHIKO
千葉医学会雑誌 44(3), 278-293, 1968
… Contraction of isolated ileum of the guinea-pig and motility of gastrointestinal tract of the unanesthetized, unrestrained rabbit were especially depressed by this drug. … As the analysis on the results of transmural electrical stimulation of the rabbit's intestine, the mode of action of CG-201 was suggested as follows : The drug affects the acetylcholine receptor and competitively antagonizes to the muscarinic actions of acetylcholine. …
NAID 110007349821

小林龍男 [他],村山智,竹本道子,松本寿枝,コバヤシタツオ,ムラヤマサトシ,タケモトミチコ,マツモトトシエ,KOBAYASHI TATSUO,MURAYAMA SATOSHI,TAKEMOTO MICHIKO,MATSUMOTO TOSHIE
千葉医学会雑誌 43(2), 214-221, 1967
… Synergistic action is observed between the effects of Methixene and barbiturates, and Methixene has cholinolytic property like atropine, but no adrenolytic potency. … and further, the drug may be usefull for premedication in general anesthesia. …
NAID 110007348325

リンク元	「抗コリン薬」「muscarinic antagonist」「anticholinergic」
関連記事	「cholinolytic」「drug」

英: anticholinergics, anticholinergic, anticholinergic agent, anticholinergic drug anticholinergic drugs, cholinolytic, cholinolytic drug, cholinergic antagonist
同: 抗コリン剤、抗コリン作用薬、コリン作用遮断薬 cholinergic blocking agent
関: ムスカリン性受容体拮抗薬 muscarinic antagonist。副交感神経遮断薬

(YN2010 抗コリン薬(神経精神))

GOO.195

呼吸器：気道分泌抑制。(アトロピンは気道分泌を抑制し、分泌物が乾固しうるが、イプラトロピウム、チオトロピウムはmucociliary clearanceにおける副作用を呈しないので、気道疾患に用いられている)
泌尿器：過活動性膀胱、夜尿症、対麻痺における頻尿
消化器：抗潰瘍薬(M1受容体選択性のある薬剤。ピレンゼピン、テレンゼピン)。鎮痙薬