WordNet

(genetics) a segment of DNA that is involved in producing a polypeptide chain; it can include regions preceding and following the coding DNA as well as introns between the exons; it is considered a unit of heredity; "genes were formerly called factors" (同)cistron, factor
the 8th letter of the Roman alphabet (同)h
informal term for information; "give me the gen on your new line of computers"

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1. 非転移性初期乳癌の予後と予後予測因子 prognostic and predictive factors in early nonmetastatic breast cancer
2. 前立腺癌の分子生物学 molecular biology of prostate cancer
3. 乳癌におけるHER2と治療の効果予測 her2 and predicting response to therapy in breast cancer
4. 頭頸部の扁平上皮癌化：分子学的および遺伝学的変化 head and neck squamous cell carcinogenesis molecular and genetic alterations
5. 転移性大腸癌に対する全身化学療法：終了した臨床試験 systemic chemotherapy for metastatic colorectal cancer completed clinical trials

The prognostic significance of p21 and Her-2 gene expression and mutation/polymorphism in patients with gastric adenocarcinoma.

Ozen A, Kocak Z, Sipahi T, Oz-Puyan F, Cakina S, Saynak M, Ibis C, Karagol H.SourceDepartment of Radiation Oncology, Medical Faculty Hospital, Trakya University, 22030, Edirne, Turkey, dralovettin@gmail.com.
Medical oncology (Northwood, London, England).Med Oncol.2013 Mar;30(1):357. doi: 10.1007/s12032-012-0357-y. Epub 2012 Dec 29.
Analyses of gene expression status and genetic polymorphisms are methods to identify novel histopathological prognostic factors. In patients with gastric cancer, some cell cycle regulators p53, p21, p27 and Her-2 oncogene have been proposed as prognostic factors. We aimed to investigate the expressi
PMID 23275116

Accurate breast cancer diagnosis through real-time PCR her-2 gene quantification using immunohistochemically-identified biopsies.

Mendoza G, Portillo A, Olmos-Soto J.SourceMolecular Microbiology Laboratory, Department of Marine Biotechnology, Center for Scientific Research and Education (CICESE);
Oncology letters.Oncol Lett.2013 Jan;5(1):295-298. Epub 2012 Oct 22.
her-2 gene amplification and its overexpression in breast cancer cells is directly associated with aggressive clinical behavior. The her-2 gene and its Her-2 protein have been utilized for disease diagnosis and as a predictive marker for treatment response to the antibody herceptin. Fluorescent in s
PMID 23255937

Suppression of HER-2 via siRNA interference promotes apoptosis and decreases metastatic potential of SKOV‑3 human ovarian carcinoma cells.

Lu YM, Rong ML, Shang C, Wang N, Li X, Zhao YY, Zhang SL.SourceDepartment of Gynaecology and Obstetrics, The Affiliated Shengjing Hospital, China Medical University, Shenyang, P.R. China.
Oncology reports.Oncol Rep.2012 Dec 28. doi: 10.3892/or.2012.2214. [Epub ahead of print]
The aberrant expression of human epidermal growth factor receptor-2 (HER-2) has been detected in ovarian cancer. However, the role of HER-2 in the development of ovarian cancer has not been sufficiently elucidated. The objective of this study was to determine the role of HER-2 in the apoptosis and m
PMID 23292493