WordNet

with pain or distress or bitterness; "he took the rejection very hard"
(of light) transmitted directly from a pointed light source (同)concentrated
with firmness; "held hard to the railing" (同)firmly
very strong or vigorous; "strong winds"; "a hard left to the chin"; "a knockout punch"; "a severe blow" (同)knockout, severe
causing great damage or hardship; "industries hit hard by the depression"; "she was severely affected by the banks failure" (同)severely
being distilled rather than fermented; having a high alcoholic content; "hard liquor" (同)strong
unfortunate or hard to bear; "had hard luck"; "a tough break" (同)tough
(of speech sounds); produced with the back of the tongue raised toward or touching the velum; "Russian distinguished between hard consonants and palatalized or soft consonants"
dispassionate; "took a hard look"; "a hard bargainer";
dried out; "hard dry rolls left over from the day before"
earnestly or intently; "thought hard about it"; "stared hard at the accused"
into a solid condition; "concrete that sets hard within a few hours"
resisting weight or pressure
slowly and with difficulty; "prejudices die hard"
to the full extent possible; all the way; "hard alee"; "the ship went hard astern"; "swung the wheel hard left"
very near or close in space or time; "it stands hard by the railroad tracks"; "they were hard on his heels"; "a strike followed hard upon the plants opening"
with effort or force or vigor; "the team played hard"; "worked hard all day"; "pressed hard on the lever"; "hit the ball hard"; "slammed the door hard"
a pattern of symptoms indicative of some disease
a complex of concurrent things; "every word has a syndrome of meanings"
the 5th letter of the Roman alphabet (同)e
the base of the natural system of logarithms; approximately equal to 2.718282...

PrepTutorEJDIC

(物体が)『堅い』,(手触りが)堅固な,しっかりした / 『難しい』,努力を要する / 《名詞の前にのみ用いて》(人が)『精力的な』,勤勉な / 激しい,猛烈な / (生活などが)耐え難い,つらい / (季節・天候などが)厳しい;(雨・風などが)激しい / (人が)厳格な;(行為などが)容赦しない,無情な / (方針・条件などが)妥協(譲歩)しない,厳しい / (感情が)うらみを含む,憤然とした / (体が)筋肉質の,がんじょうな / (紙幣に対して)硬貨の,(小切手などに対して)現金の;(貨幣が)容易に兌換(だかん)できる / (子音が)硬音の(c,gがcome, goのように[k],[g]と発音される) / アルコール分の多い / (水が)硬質の / (エックス線が)透過能力が大きい / 一生懸命に,『熱心に』 / 『強く』,激しく,大いに / やっと,かろうじて / 『堅く』 / ひどく悲んで / 接近して
(疾患の徴候となる一群の)症徴候,症候群 / (事件・社会的状態などのパターンを示す)徴候形態
einsteiniumの化学記号

UpToDate Contents

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1. 悪性症候群 neuroleptic malignant syndrome
2. 口唇口蓋裂の病因、出生前診断、産科マネージメント、および再発 etiology prenatal diagnosis obstetrical management and recurrence of orofacial clefts
3. 亜急性または慢性の手首の疼痛を有する成人の評価 evaluation of the adult with subacute or chronic wrist pain
4. 鎌状赤血球症を有する小児に対する定期的な包括的ケア routine comprehensive care for children with sickle cell disease
5. 表皮水疱症の疫学、病因および臨床的特徴 epidemiology pathogenesis and clinical features of epidermolysis bullosa

English Journal

Walker-Warburg Syndrome Manifesting as Leopard Spot Retinopathy, Retinal Detachment, and Microphthalmia.

Park SH, Shin SY.
Journal of pediatric ophthalmology and strabismus.J Pediatr Ophthalmol Strabismus.2009 Oct 2. doi: 10.3928/01913913-20090918-09. Epub 2009 Oct 2.
Walker-Warburg syndrome, also known as HARD+/-E, is a congenital autosomal recessive disorder characterized by hydrocephalus, agyria, and retinal dysplasia, with or without encephalocele. The authors describe an infant with Walker-Warburg syndrome who presented with microphthalmia, retinal detachmen
PMID 19791710