WordNet

the 2nd letter of the Roman alphabet (同)b
the blood group whose red cells carry the B antigen (同)type_B, group B
any of several malignant neoplasms (usually of the skin) consisting of melanocytes (同)malignant_melanoma

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In search of a novel target - Phosphatidylserine exposed by non-apoptotic tumor cells and metastases of malignancies with poor treatment efficacy.

Riedl S, Rinner B, Asslaber M, Schaider H, Walzer S, Novak A, Lohner K, Zweytick D.SourceInstitute of Biophysics and Nanosystems Research, Austrian Academy of Sciences, Schmiedlstrase 6, A-8042 Graz, Austria.
Biochimica et biophysica acta.Biochim Biophys Acta.2011 Nov;1808(11):2638-45. Epub 2011 Jul 26.
This study was performed in the aim to identify potential targets for the development of novel therapy to treat cancer with poor outcome or treatment efficacy. We show that the negatively charged phospholipid phosphatidylserine (PS) is exposed in the outer leaflet of their plasma membrane not only i
PMID 21810406

Diethylstilbestrol enhances melanogenesis via cAMP-PKA-mediating up-regulation of tyrosinase and MITF in mouse B16 melanoma cells.

Jian D, Jiang D, Su J, Chen W, Hu X, Kuang Y, Xie H, Li J, Chen X.SourceDepartment of Dermatology, XiangYa Hospital, Central South University, Changsha, Hunan, China.
Steroids.Steroids.2011 Nov;76(12):1297-304. Epub 2011 Jun 30.
BACKGROUND: It is well known that melanin synthesis in melanoma cells is controlled by melanogenic enzymes, which regulate the cAMP-PKA signaling pathway. Estrogen was previously reported to upregulate melanogenesis that is associated with human skin pigmentation.OBJECTIVE: To investigate the influe
PMID 21745488

Sato Kazuomi,Takahashi Hideki,Toriyama Masaru
Archives of dermatological research 303(3), 171-180, 2011-04
… Mefenamic acid, diclofenac, and nimesulide were used in this study, and these drugs inhibit melanin synthesis in B16F1 melanoma cells. …
NAID 120003273776

Effects of coating materials and size of titanium dioxide particles on their cytotoxicity and penetration into the cellular membrane

UCHINO Tadashi,IKARASHI Yoshiaki,NISHIMURA Tetsuji
Journal of toxicological sciences 36(1), 95-100, 2011-02-01
… In order to estimate the effects of the size and surface treatment (coating or non-coating) of titanium dioxide particles on their cytotoxicity and penetration into the cellular membrane, two types of non-treated titanium dioxide (TiO2) particles of 20 nm (LU175) and 250 nm (LU205) were exposed to CHO cells, RBL-2H3 cells, A431 cells, B16 melanoma, NHEK(F), and NHSF, and six types of surface-treated or non-treated TiO2 particles of 35 nm were exposed to RBL-2H3 cells and NHSF. …
NAID 10027420477