WordNet

the 19th letter of the Roman alphabet (同)s
any of several malignant neoplasms (usually of the skin) consisting of melanocytes (同)malignant_melanoma

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SCD5-induced oleic acid production reduces melanoma malignancy by intracellular retention of SPARC and cathepsin B.

Bellenghi M1, Puglisi R1, Pedini F1, De Feo A1, Felicetti F1, Bottero L1, Sangaletti S2, Errico MC1, Petrini M1, Gesumundo C3, Denaro M3, Felli N1, Pasquini L1, Tripodo C4, Colombo MP2, Carè A1, Mattia G1.
The Journal of pathology.J Pathol.2015 Jul;236(3):315-25. doi: 10.1002/path.4535. Epub 2015 Apr 20.
A proper balance between saturated and unsaturated fatty acids (FAs) is required for maintaining cell homeostasis. The increased demand of FAs to assemble the plasma membranes of continuously dividing cancer cells might unbalance this ratio and critically affect tumour outgrowth. We unveiled the rol
PMID 25802234

Enhancing dendritic cell immunotherapy for melanoma using a simple mathematical model.

Castillo-Montiel E1, Chimal-Eguía JC2, Tello JI3, Piñon-Zaráte G4, Herrera-Enríquez M5, Castell-Rodríguez A6.
Theoretical biology & medical modelling.Theor Biol Med Model.2015 Jun 9;12(1):11. [Epub ahead of print]
BACKGROUND: The immunotherapy using dendritic cells (DCs) against different varieties of cancer is an approach that has been previously explored which induces a specific immune response. This work presents a mathematical model of DCs immunotherapy for melanoma in mice based on work by Experimental I
PMID 26054860

Optimization of Purification, Identification and Evaluation of the in Vitro Antitumor Activity of Polyphenols from Pinus Koraiensis Pinecones.

Yi J1, Wang Z2,3, Bai H1, Yu X4, Jing J1, Zuo L5.
Molecules (Basel, Switzerland).Molecules.2015 Jun 5;20(6):10450-67. doi: 10.3390/molecules200610450.
In this study, an efficient purification method for the polyphenols of Pinus koraiensis pinecone (PPP) has been developed. AB-8 resin was verified to offer good adsorption and desorption ratio for PPP. Response surface methodology (RSM) indicated that the optimized purification parameters for PPP we
PMID 26056816