WordNet

derived from organisms of a different but related species; "a heterologous graft"
not corresponding in structure or evolutionary origin (同)heterologic, heterological
any substance (as a toxin or enzyme) that stimulates an immune response in the body (especially the production of antibodies)

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A dual purpose universal influenza vaccine candidate confers protective immunity against anthrax.

Arévalo MT1, Li J1, Diaz-Arévalo D1, Chen Y1, Navarro A1, Wu L1,2, Yan Y1,2, Zeng M1.
Immunology.Immunology.2017 Mar;150(3):276-289. doi: 10.1111/imm.12683. Epub 2016 Dec 5.
Preventive influenza vaccines must be reformulated annually because of antigen shift and drift of circulating influenza viral strains. However, seasonal vaccines do not always match the circulating strains, and there is the ever-present threat that avian influenza viruses may adapt to humans. Hence,
PMID 27775159

Dhakal S1, Goodman J2, Bondra K1, Lakshmanappa YS1, Hiremath J1, Shyu DL1, Ouyang K1, Kang KI1, Krakowka S3, Wannemuehler MJ4, Won Lee C1, Narasimhan B2, Renukaradhya GJ5.
Vaccine.Vaccine.2017 Feb 22;35(8):1124-1131. doi: 10.1016/j.vaccine.2017.01.019. Epub 2017 Jan 20.
We have recently demonstrated the effectiveness of an influenza A virus (IAV) subunit vaccine based on biodegradable polyanhydride nanoparticles delivery in mice. In the present study, we evaluated the efficacy of ∼200nm polyanhydride nanoparticles encapsulating inactivated swine influenza A virus
PMID 28117173

The localization of a heterologous displayed antigen in the baculovirus-budded virion determines the type and strength of induced adaptive immune response.

Tavarone E1,2, Molina GN1,2, Amalfi S1,2, Peralta A1,2, Molinari P1,2, Taboga O3,4.
Applied microbiology and biotechnology.Appl Microbiol Biotechnol.2017 Feb 17. doi: 10.1007/s00253-017-8183-y. [Epub ahead of print]
In the search of strategies of presentation of heterologous antigens to elicit humoral or cellular immune responses that modulate and properly potentiate each type of response, researchers have been studying baculovirus (BV) as vaccine vectors with promising results. For some years, several research
PMID 28213733

Expression of an antibody-enzyme complex by the L-chain fusion method(ENZYMOLOGY, PROTEIN ENGINEERING, AND ENZYME TECHNOLOGY)

Development of a Novel Mouse Anaphylaxis Model Produced by Intermittent Intravenous Injections of Ovalbumin without Adjuvant

Bacillus subtilis AprX Involved in Degradation of a Heterologous Protein During the Late Stationary Growth Phase(GENETICS, MOLECULAR BIOLOGY, AND GENE ENGINEERING)