factor VIII deficiency

出典: meddic


haemophiliahemophiliahemophilia A

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2018/05/02 19:09:06」(JST)

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  • BAY 81-8973, a full-length recombinant factor VIII: Human heat shock protein 70 improves the manufacturing process without affecting clinical safety.
  • Maas Enriquez M1, Thrift J2, Garger S3, Katterle Y4.
  • Protein expression and purification.Protein Expr Purif.2016 Nov;127:111-5. doi: 10.1016/j.pep.2016.07.009. Epub 2016 Jul 18.
  • BAY 81-8973 is a full-length, unmodified recombinant human factor VIII (FVIII) approved for the treatment of hemophilia A. BAY 81-8973 has the same amino acid sequence as the currently marketed sucrose-formulated recombinant FVIII (rFVIII-FS) product and is produced using additional advanced manufac
  • PMID 27436242
  • Acquired hemophilia A associated with myasthenia gravis and Isaacs' syndrome.
  • Takeda T1, Konno A2, Kazama T2, Suzuki M2, Shimizu Y2, Iijima M2, Tanaka J3, Kitagawa K2.
  • Journal of the neurological sciences.J Neurol Sci.2016 Oct 15;369:210-1. doi: 10.1016/j.jns.2016.08.032. Epub 2016 Aug 16.
  • PMID 27653890
  • The safety of pharmacologic options for the treatment of persons with hemophilia.
  • Franchini M1, Mannucci PM2.
  • Expert opinion on drug safety.Expert Opin Drug Saf.2016 Oct;15(10):1391-400. doi: 10.1080/14740338.2016.1208747. Epub 2016 Jul 18.
  • INTRODUCTION: The mainstay of treatment of hemophilia A and B is the replacement of the congenitally deficient coagulation factor through the intravenous infusion of specific concentrates (factor VIII, FVIII, in hemophilia A; factor IX, FIX, in hemophilia B). Several commercial brands of FVIII or FI
  • PMID 27367551


  • Embolization for Refractory Subacute Subdural Hematoma in a Child with Severe Hemophilia Type A
  • IgG4関連疾患に合併した後天性凝固第V因子欠乏症の1例
  • von Willebrand因子の構造とvon Willebrand病


Factor VIII (antihaemophilic factor) deficiency (Type A) is a common X-linked genetic form of canine hemophilia. Factor VIII is a trace plasma glycoprotein involved as a cofactor in the activation of factor X by factor IXa. A deficiency in ...
Factor VIII deficiency Haemophilia A (also spelt Hemophilia A or Hæmophilia A) is a blood clotting disorder caused by a mutation of the factor VIII gene, leading to a deficiency in Factor VIII. It is the most common hemophilia.


Factor VIII Factor VIII Deficiency; HemophiliaEntity page for factor VIII deficiencyEntity page for factor VIII deficiencyDisorders of Hemostasis - Crashing Patient : Hemophilia A (Factor VIII deficiency



  [★] 血友病

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「congenital tendency to uncontrolled bleeding; usually affects males and is transmitted from mother to son」
haemophilia, bleeder''s disease

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factor VIII deficiencyhaemophilichemophiliahemophilia Ahemophiliachemophilic



factor VIII deficiency



factor VIII deficiency



  • n.

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「be a contributing factor; "make things factor into a company''s profitability"」

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「any of the numbers (or symbols) that form a product when multiplied together」

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「an independent variable in statistics」

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「anything that contributes causally to a result; "a number of factors determined the outcome"」

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「(…の)『要因』,(…を生み出す)要素《+『in』+『名』(do『ing』)》 / 囲数,約数 / 代理人,《おもに英》仲買人 / =factorize」

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「consider as relevant when making a decision; "You must factor in the recent developments"」
factor in, factor out

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「resolve into factors; "a quantum computer can factor the number 15"」
factor in, factor out



  • n.
actualactuallyin factin practiceindeedpractically

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「an event known to have happened or something known to have existed; "your fears have no basis in fact"; "how much of the story is fact and how much fiction is hard to tell"」

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「a concept whose truth can be proved; "scientific hypotheses are not facts"」

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「a piece of information about circumstances that exist or events that have occurred; "first you must collect all the facts of the case"」

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「a statement or assertion of verified information about something that is the case or has happened; "he supported his argument with an impressive array of facts"」

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「〈C〉『事実』,実際にある(あった)事 / 〈U〉真相,真実(truth) / 《the~》(法律用語で)犯行」



  • n.
  • 不足、欠乏、欠失、欠如、欠損、不十分。栄養不足、栄養素欠乏、欠乏症。(遺伝子)(染色体内の)遺伝子欠失
  • 欠けているもの、不足している物。不足分。不完全なもの、欠点のあるもの
absence, agenesis, dearth, defect, defective, deficient, deficit, delete, deletion, deletional, depletion, deprivation, deprive, lack, miss, missing, morphological defect, paucity, scarce, scarcity, starve

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「〈U〉〈C〉(…の)(量・額などの)不足,欠乏《+『of』(『in』)+『名』》 / 〈C〉不足分,不足量,不足額 / 〈C〉(精神・肉体などの)欠陥」



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