WordNet
- be a contributing factor; "make things factor into a companys profitability"
- any of the numbers (or symbols) that form a product when multiplied together
- an independent variable in statistics
- anything that contributes causally to a result; "a number of factors determined the outcome"
- consider as relevant when making a decision; "You must factor in the recent developments" (同)factor in, factor out
- resolve into factors; "a quantum computer can factor the number 15" (同)factor in, factor out
- an event known to have happened or something known to have existed; "your fears have no basis in fact"; "how much of the story is fact and how much fiction is hard to tell"
- a concept whose truth can be proved; "scientific hypotheses are not facts"
- a piece of information about circumstances that exist or events that have occurred; "first you must collect all the facts of the case"
- a statement or assertion of verified information about something that is the case or has happened; "he supported his argument with an impressive array of facts"
- an addition to the length of something (同)extension
- the act of lengthening something
- the quality of being elongated
- an enzyme that catalyzes the conversion of a proenzyme to an active enzyme
- the basic unit of money in Papua New Guinea
PrepTutorEJDIC
- (…の)『要因』,(…を生み出す)要素《+『in』+『名』(do『ing』)》 / 囲数,約数 / 代理人,《おもに英》仲買人 / =factorize
- 〈C〉『事実』,実際にある(あった)事 / 〈U〉真相,真実(truth) / 《the~》(法律用語で)犯行
- 〈U〉伸長,延長 / 〈C〉伸長部,延長部
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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/03/19 00:08:51」(JST)
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- 1. 先天性赤血球増多症および真性多血症の分子学的病因 molecular pathogenesis of congenital polycythemic disorders and polycythemia vera
- 2. GISTを含む消化管間葉系腫瘍の疫学、分類、臨床像、予後の特徴、および診断方法 epidemiology classification clinical presentation prognostic features and diagnostic work up of gastrointestinal mesenchymal neoplasms including gist
- 3. 骨髄増殖性腫瘍の概要 overview of the myeloproliferative neoplasms
- 4. 高グレードの神経膠腫に対する実験的治療アプローチ experimental treatment approaches for high grade gliomas
- 5. 脊髄小脳変性症 the spinocerebellar ataxias
English Journal
- Application of Eukaryotic Elongation Factor-2 Kinase (eEF-2K) for Cancer Therapy: Expression, Purification, and High-Throughput Inhibitor Screening.
- Tavares CD1, Devkota AK2, Dalby KN3,4, Cho EJ5,6.
- Methods in molecular biology (Clifton, N.J.).Methods Mol Biol.2016;1360:19-33. doi: 10.1007/978-1-4939-3073-9_2.
- Protein kinases have emerged as an important class of therapeutic targets, as they are known to be involved in pathological pathways linked to numerous human disorders. Major efforts to discover kinase inhibitors in both academia and pharmaceutical companies have centered on the development of robus
- PMID 26501899
- Eukaryotic elongation factor 2 kinase regulates the synthesis of microtubule-related proteins in neurons.
- Kenney JW1, Genheden M1, Moon KM2, Wang X1, Foster LJ2, Proud CG1.
- Journal of neurochemistry.J Neurochem.2015 Oct 20. doi: 10.1111/jnc.13407. [Epub ahead of print]
- Modulation of the elongation phase of protein synthesis is important for numerous physiological processes in both neurons and other cell types. Elongation is primarily regulated via eukaryotic elongation factor 2 kinase (eEF2K). However, the consequence of altering eEF2K activity on the synthesis of
- PMID 26485687
- Spontaneous neurotransmission signals through store-driven Ca(2+) transients to maintain synaptic homeostasis.
- Reese AL1, Kavalali ET1.
- eLife.Elife.2015 Jul 24;4. doi: 10.7554/eLife.09262.
- Spontaneous glutamate release-driven NMDA receptor activity exerts a strong influence on synaptic homeostasis. However, the properties of Ca(2+) signals that mediate this effect remain unclear. Here, using hippocampal neurons labeled with the fluorescent Ca(2+) probes Fluo-4 or GCAMP5, we visualized
- PMID 26208337
Japanese Journal
- Histone deacetylase inhibitors suppress mechanical stress-induced expression of RUNX-2 and ADAMTS-5 through the inhibition of the MAPK signaling pathway in cultured human chondrocytes
- Saito T.,Nishida K.,Furumatsu T.,Yoshida A.,Ozawa M.,Ozaki T.
- Osteoarthritis and Cartilage 21(1), 165-174, 2013-01
- … Objective: To investigate the inhibitory effects and the regulatory mechanisms of histone deacetylase (HDAC) inhibitors on mechanical stress-induced gene expression of runt-related transcription factor (RUNX)-2 and a disintegrin and metalloproteinase with thrombospondin motif (ADAMTS)-5 in human chondrocytes. … TSA) for 12 h, followed by uniaxial cyclic tensile strain (CTS) (0.5 Hz, 10% elongation), which was applied for 30 min using the ST-140-10 system (STREX, Osaka, Japan). …
- NAID 120005311990
- Control of muscle protein synthesis in response to exercise and amino acids
- Nakai Naoya,Kawano Fuminori,Ohira Yoshinobu
- The Journal of Physical Fitness and Sports Medicine 1(2), 297-305, 2012
- … The intracellular signaling pathways through the mammalian target of rapamycin (mTOR), a serine/threonine protein kinase, are the most established mechanism for controlling muscle protein synthesis. … Acute bouts of resistance exercise and amino acid ingestion independently activate mTOR and its downstream targets that modulate protein translation initiation and elongation. …
- NAID 130001930870
- The β1-integrin-dependent function of RECK in physiologic and tumor angiogenesis
- Miki Takao,Shamma Awad,Kitajima Shunsuke,Takegami Yujiro,Noda Makoto,Nakashima Yasuaki,Watanabe Kenichiro,Takahashi Chiaki
- Molecular Cancer Research 8(5), 655-676, 2010-05
- … Here, we show that an angiogenic factor angiopoietin-1 induces RECK expression in human umbilical vein endothelial cells (HUVEC), and RECK depletion in these cells results in defective vascular tube formation and cellular senescence. … We further observed that RECK depletion downregulates β1-integrin activation, which was associated with decreased autophosphorylation of focal adhesion kinase and increased expression of a cyclin-dependent kinase inhibitor p21CIP1. …
- NAID 120002224338
Related Links
- This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis.
- Publications, Research Grants, Research Topics, Genomes and Genes, Species, Scientific Experts about elongation factor 2 kinase ... Kathryn J Huber-Keener Department of Pharmacology and The Penn State Hershey Cancer ...
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★リンクテーブル★
| リンク元 | 「伸長因子2キナーゼ」 |
| 関連記事 | 「elongation」「fact」「factor」「kinase」 |
「伸長因子2キナーゼ」
「elongation」
- n.
「fact」
- n.
「factor」
- n.