cyclic guanosine monophosphate

出典: meddic


cyclic GMPcyclic guanosine 3',5'-monophosphate


  • New NSAID targets and derivatives for colorectal cancer chemoprevention.
  • Tinsley HN, Grizzle WE, Abadi A, Keeton A, Zhu B, Xi Y, Piazza GA.SourceDepartment of Biology, University of Montevallo, Montevallo, AL, USA.
  • Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer.Recent Results Cancer Res.2013;191:105-20. doi: 10.1007/978-3-642-30331-9_6.
  • Clinical and preclinical studies provide strong evidence that nonsteroidal anti-inflammatory drugs (NSAIDs) can prevent numerous types of cancers, especially colorectal cancer. Unfortunately, the depletion of physiologically important prostaglandins due to cyclooxygenase (COX) inhibition results in
  • PMID 22893202
  • Characterization of nitric oxide signaling pathways in the mouse retina.
  • Blom J, Giove T, Deshpande M, Eldred WD.SourceDepartment of Biology, Boston University, Boston, Massachusetts 02215.
  • The Journal of comparative neurology.J Comp Neurol.2012 Dec 15;520(18):4204-17. doi: 10.1002/cne.23148.
  • Nitric oxide (NO) is a gaseous neuromodulator with physiological functions in every retinal cell type. NO is synthesized by several nitric oxide synthases (NOS) and often functions through its second messenger, cyclic guanosine monophosphate (cGMP), and protein kinase G (PKG). This study combined NO
  • PMID 22592770


  • FOCUS REVIEWS ON CARDIOVASCULAR PROTECTION : Molecular Variants of Soluble Guanylyl Cyclase Affecting Cardiovascular Risk
  • Wobst Jana,Rumpf Philipp Moritz,Dang Tan An [他]
  • Circulation journal : official journal of the Japanese Circulation Society 79(3), 463-469, 2015-03
  • NAID 40020374715
  • Intracellular cyclic adenosine monophosphate regulates the efficiency of intercellular transmission of human T-lymphotropic virus type I
  • Nakamura Tatsufumi,Satoh Katsuya,Nakamura Hideki,Yamasaki Hironori
  • Clinical and Experimental Neuroimmunology 5(2), 209-215, 2014-06
  • … The intracellular levels of cyclic adenosine monophosphate (cAMP) or cyclic guanosine monophosphate (cGMP) were measured in enzyme-linked immunoassays. …
  • NAID 120005476999
  • Antiplatelet Effects of Caffeic Acid Due to Ca2+ MobilizationInhibition Via cAMP-Dependent Inositol-1, 4, 5-Trisphosphate Receptor Phosphorylation
  • , , , , ,
  • Journal of Atherosclerosis and Thrombosis 21(1), 23-37, 2014
  • … In this study, we investigated the effects of caffeic acid (CAFA), a phenolic acid, on Ca2+-antagonistic cyclic nucleotides associated with the phosphorylation of inositol 1,4,5-trisphosphate receptor (IP3R) and vasodilator-stimulated phosphoprotein (VASP) and the thromboxane A2 (TXA2)-associated microsomal cyclooxygenase-1 (COX-1) activity in collagen (10 μg/mL)-stimulated platelet aggregation.Methods: Washed platelets (108/mL) obtained from Sprague-Dawley rats (6-7 weeks old, male) were preincubated for 3 minutes at 37℃ in the presence of 2 mM …
  • NAID 130004845457


cyclic guanosine monophosphate n. Cyclic GMP. cyclic guanosine monophosphate (cGMP), a substance that mediates the action of certain hormones in a manner similar to that of cyclic adenosine monophosphate. In response to ...
cyclic guanosine monophosphate n. Cyclic GMP. cyclic guanosine monophosphate (cGMP), a substance that mediates the action of certain hormones in a manner similar to that of cyclic adenosine monophosphate. In response to ...



リンク元環状グアノシン一リン酸」「cyclic guanosine 3',5'-monophosphate
関連記事cyclic」「monophosphate」「guanosine monophosphate



cyclic GMP cGMP
環状GMP、サイクリックグアノシン3',5'-一リン酸 cyclic guanosine 3',5'-monophosphate


  • 細胞内でセカンドメッセンジャーとして機能
  • 血管壁:cGMP上昇 → 血管収縮。
  • sildenafil citrateはPDE5を阻害してcGMPの分解を抑制することで血管を拡張させる。



cyclic guanosine monophosphatecyclic GMP

cyclic guanosine 3',5'-monophosphate」


cyclic GMPcyclic guanosine monophosphate



  • adj.

WordNet   license wordnet

「of a compound having atoms arranged in a ring structure」

WordNet   license wordnet

「recurring in cycles」

WordNet   license wordnet

「conforming to the Carnot cycle」

WordNet   license wordnet

「forming a whorl or having parts arranged in a whorl; "cyclic petals"; "cyclic flowers"」

WordNet   license wordnet

「marked by repeated cycles」



  • n.

guanosine monophosphate」

  [★] グアノシン一リン酸GMP