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1. 変形性関節症の初回薬物療法 initial pharmacologic therapy of osteoarthritis
2. 過敏性腸症候群に対するアロセトロン塩酸塩（Lotronex） alosetron hydrochloride lotronex for irritable bowel syndrome
3. クリンダマイシン：概要 clindamycin an overview
4. 成人における急性咽頭炎の対症療法 symptomatic treatment of acute pharyngitis in adults
5. 慢性非アレルギー性鼻炎 chronic nonallergic rhinitis

Levodropropizine for treating cough in adult and children: a meta-analysis of published studies.

Zanasi A1, Lanata L2, Fontana G3, Saibene F2, Dicpinigaitis P4, De Blasio F5.
Multidisciplinary respiratory medicine.Multidiscip Respir Med.2015 May 31;10(1):19. doi: 10.1186/s40248-015-0014-3. eCollection 2015.
BACKGROUND: Cough is one of the most common symptoms for which patients seek medical attention from primary care physicians and lung specialists. About 40% of the population at any one time report cough. Cough is associated with significantly impaired health-related quality of life. Levodropropizine
PMID 26097707

Cloperastine rescues impairment of passive avoidance response in mice prenatally exposed to diethylstilbestrol.

Soeda F1, Hirakawa E, Inoue M, Shirasaki T, Takahama K.
Environmental toxicology.Environ Toxicol.2014 Feb;29(2):216-25. doi: 10.1002/tox.21749. Epub 2012 Jan 5.
We previously reported that prenatal exposure to diethylstilbestrol (DES) impaired passive avoidance responses in mice. Apart from the above, we also found that cloperastine, a centrally acting antitussive, ameliorated depression-like and anxiety-like behaviors in rodents at antitussive-effective do
PMID 22223406

Gregori-Puigjané E1, Setola V, Hert J, Crews BA, Irwin JJ, Lounkine E, Marnett L, Roth BL, Shoichet BK.
Proceedings of the National Academy of Sciences of the United States of America.Proc Natl Acad Sci U S A.2012 Jul 10;109(28):11178-83. doi: 10.1073/pnas.1204524109. Epub 2012 Jun 18.
Notwithstanding their key roles in therapy and as biological probes, 7% of approved drugs are purported to have no known primary target, and up to 18% lack a well-defined mechanism of action. Using a chemoinformatics approach, we sought to "de-orphanize" drugs that lack primary targets. Surprisingly
PMID 22711801