adhesion molecule

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/08/02 17:23:03」(JST)

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  • Analysis of cell surface antigens by Surface Plasmon Resonance imaging.
  • Stojanović I, Schasfoort RB, Terstappen LW.SourceMedical Cell Biophysics Group, MIRA institute, Faculty of Science and Technology, University of Twente, PO Box 217, 7500AE Enschede, The Netherlands. Electronic address:
  • Biosensors & bioelectronics.Biosens Bioelectron.2014 Feb 15;52:36-43. doi: 10.1016/j.bios.2013.08.027. Epub 2013 Aug 27.
  • Surface Plasmon Resonance (SPR) is most commonly used to measure bio-molecular interactions. SPR is used significantly less frequent for measuring whole cell interactions. Here we introduce a method to measure whole cells label free using the specific binding of cell surface antigens expressed on th
  • PMID 24016537
  • COUP-TFII inhibits NFkappaB activation in endocrine-resistant breast cancer cells.
  • Litchfield LM, Appana SN, Datta S, Klinge CM.SourceDepartment of Biochemistry & Molecular Biology, Center for Genetics and Molecular Medicine, University of Louisville School of Medicine, Louisville, KY 40292, USA.
  • Molecular and cellular endocrinology.Mol Cell Endocrinol.2014 Jan 25;382(1):358-67. doi: 10.1016/j.mce.2013.10.010. Epub 2013 Oct 17.
  • Reduced COUP-TFII expression contributes to endocrine resistance in breast cancer cells. Endocrine-resistant breast cancer cells have higher NFkappa B (NFκB) activity and target gene expression. The goal of this study was to determine if COUP-TFII modulates NFκB activity. Endocrine-resistant LCC9
  • PMID 24141032
  • mRNA and miRNA expression patterns associated to pathways linked to metal mixture health effects.
  • Martínez-Pacheco M, Hidalgo-Miranda A, Romero-Córdoba S, Valverde M, Rojas E.SourceUniversidad Nacional Autónoma de México, Instituto de Investigaciones Biomédicas, Departamento de Medicina Genómica y Toxicología Ambiental, C.U., 04510 México, México.
  • Gene.Gene.2014 Jan 10;533(2):508-14. doi: 10.1016/j.gene.2013.09.049. Epub 2013 Sep 27.
  • Metals are a threat to human health by increasing disease risk. Experimental data have linked altered miRNA expression with exposure to some metals. MiRNAs comprise a large family of non-coding single-stranded molecules that primarily function to negatively regulate gene expression post-transcriptio
  • PMID 24080485


  • Cyclosporine Nanomicelle Eye Drop : A Novel Medication for Corneal Graft Transplantation Treatment
  • Zhang Hongkui,Wang Ling,Zhang Longlu
  • Biological & pharmaceutical bulletin 38(6), 893-900, 2015-06
  • NAID 40020471511
  • The Cell Adhesion Molecule Necl-4/CADM4 Serves as a Novel Regulator for Contact Inhibition of Cell Movement and Proliferation
  • Yamana Shota,Tokiyama Amina,Mizutani Kiyohito,Hirata Ken-ichi,Takai Yoshimi,Rikitake Yoshiyuki
  • PLoS ONE 10(4), e0124259, 2015-04-20
  • NAID 120005611305
  • Direct Infection of Primary Salivary Gland Epithelial Cells by Human T Lymphotropic Virus Type I in Patients With Sjögren's Syndrome
  • Nakamura Hideki,Takahashi Yoshiko,Yamamoto-Fukuda Tomomi,Horai Yoshiro,Nakashima Yoshikazu,Arima Kazuhiko,Nakamura Tatsufumi,Koji Takehiko,Kawakami Atsushi
  • Arthritis & Rheumatology 67(4), 1096-1106, 2015-04
  • … After coculture of SGECs with HCT-5, the expression of cytokines and chemokines, including soluble intercellular adhesion molecule 1, RANTES, and interferon γ-induced protein 10 kd (IP-10/CXCL10) was increased in a time-dependent manner. …
  • NAID 120005603845




拡張検索cell adhesion molecule」「platelet endothelial cell adhesion molecule-1」「intercellular adhesion molecule-1」「activated-leukocyte cell adhesion molecule



adhesion molecule


白血球の相互作用に関与している接着分子 (IMM.87)

グループ名 機能 名称 別名 組織分布 リガンド
セレクチン 炭化水素鎖に結合。
P-selectin PADGEN CD62P 活性化した内皮細胞、活性化した血小板 PSGL-1, sialyl-Lewisx
E-selectin ELAM-1 CD62E 活性化した内皮細胞 sialyl-Lewisx
インテグリン CAMや細胞外マトリックスに結合。
LFA-1 αL:β2 CD11a:CD18 単球、T細胞、マクロファージ、好中球、樹状細胞 ICAMs
CR3, Mac-1 αM:β2 CD11b:CD18 好中球、単球、マクロファージ ICAM-1, iC3b, fibrinogen
CR4, p150.95 αX:β2 CD11c:CD18 樹状細胞、マクロファージ、好中球 iC3b
VLA-5 α5:β1 CD49d:CD29 単球、マクロファージ fibronectin
免疫グロブリンスーパーファミリー 細胞結合で様々に働く。
ICAM-1   CD54 活性化した内皮細胞 LFA-1, MAC1
ICAM-2   CD102 非活性化状態の内皮細胞、樹状細胞 LFA-1
VCAM-1   CD106 活性化した内皮細胞 VLA-4
PECAM   CD31 活性化した白血球、内皮細胞間の結合 CD31

白血球の相互作用に関与している免疫グロブリンスーパーファミリーの接着分子 (IMM.329)

名称 分布組織 リガンド
CD2 LFA-2 T細胞 LFA-1 CD53
ICAM-1 CD54 活性化した血管、リンパ球、樹状細胞 LFA-1, Mac-1  
ICAM-2 CD102 非活性化状態の血管 LFA-1  
ICAM-3 CD50 Naive T cells DC-SIGN, LFA-1  
LFA-3 CD58 リンパ球、APC CD2  
VCAM-1 CD106 活性化した内皮細胞 VLA-4  

cell adhesion molecule」


CAMICAMintercellular adhesion moleculeleukocyte adhesion molecule

platelet endothelial cell adhesion molecule-1」



CD31 antigenPECAM-1

intercellular adhesion molecule-1」



activated-leukocyte cell adhesion molecule」






  • n

WordNet   license wordnet

「a fibrous band of scar tissue that binds together normally separate anatomical structures」

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「abnormal union of bodily tissues; most common in the abdomen」

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WordNet   license wordnet

「(physics and chemistry) the simplest structural unit of an element or compound」

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「分子《略》『mol』) / (一般に)(…の)微量《+『of』+『名』》」