Pseudo-Pelger-Huet anomaly

偽ペルゲル・フェット核異常

WordNet

1. deviation from the normal or common order or form or rule (同)anomalousness
2. a person who is unusual (同)unusual person
3. (astronomy) position of a planet as defined by its angular distance from its perihelion (as observed from the sun)
4. (often used in combination) not genuine but having the appearance of; "a pseudo esthete"; "pseudoclassic"

PrepTutorEJDIC

1. 〈U〉〈C〉変則,例外;異常 / 〈C〉変則的な事態,異例な人(物)
2. 偽りの;見せかけの

UpToDate Contents

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• 1. 骨髄異形成症候群の臨床症状および診断 clinical manifestations and diagnosis of the myelodysplastic syndromes
• 2. 好中球増多症の原因 causes of neutrophilia
• 3. 好中球二次顆粒欠損症 neutrophil specific granule deficiency
• 4. 貧食細胞機能の原発性疾患：概要 primary disorders of phagocytic function an overview
• 5. 末梢血塗抹標本の評価 evaluation of the peripheral blood smear

English Journal

• Dicer1 deletion in myeloid-committed progenitors causes neutrophil dysplasia and blocks macrophage/dendritic cell development in mice.

• Alemdehy MF, van Boxtel NG, de Looper HW, van den Berge IJ, Sanders MA, Cupedo T, Touw IP, Erkeland SJ.SourceDepartment of Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands.
• Blood.Blood.2012 May 17;119(20):4723-30. Epub 2012 Feb 21.
• MicroRNAs (miRNAs) have the potential to regulate cellular differentiation programs; however, miRNA deficiency in primary hematopoietic stem cells (HSCs) results in HSC depletion in mice, leaving the question of whether miRNAs play a role in early-lineage decisions un-answered. To address this issue
• PMID 22353998

• Understanding and recognizing the Pelger-Huët anomaly.

• Colella R, Hollensead SC.SourceDepartment of Anatomical Sciences and Neurobiology, University of Louisville School of Medicine, Louisville, KY 40292, USA.
• American journal of clinical pathology.Am J Clin Pathol.2012 Mar;137(3):358-66.
• The Pelger-Huët anomaly (PHA) is a recognized morphologic variant affecting all granulocytes but is most evident in polymorphonuclear neutrophils (PMNs). PHA is caused by a decreased amount of the lamin B receptor (LBR). Recognition of PHA morphologic features serves as a marker for mutations in th
• PMID 22338047

Japanese Journal

• Pseudo-Pelger-Huet anomaly induced by transplant medications

• WANG Endi,KULBACKI Evan
• International journal of hematology 92(1), 1-2, 2010-07-15
• NAID 10026511567

• 好中球の Pelger-Huet 核異常をめぐって ; 血液形態学の進化

• 朝長 万左男
• 臨床病理 = THE OFFICIAL JOURNAL OF JAPANESE SOCIETY OF LABORATORY MEDICINE 53(1), 54-60, 2005-01-25
• NAID 10014390226

Related Links

• Pelger-Huet Anomaly: Background, Pathophysiology ...

Distinguishing this benign autosomal dominant disorder from acquired or pseudo–Pelger-Huët anomaly, which can be observed in individuals with myeloid leukemia , myelodysplasia, and bi-lineage acute lymphocytic leukemia, is ...

• Pseudo Pelger-Huët Anomaly - ASH Image Bank

Wright stain showing a Pseudo-Pelger-Huet neutrophil and a band on the peripheral blood of a patient with a Chronic Myeloproliferative Disorder, Unclassified. Pelger-Huet anomaly is an autosomal dominant benign disorder, while ...

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★リンクテーブル★

リンク元	「偽ペルゲル・フェット核異常」
関連記事	「anomaly」「pseudo」

「偽ペルゲル・フェット核異常」

　　[★]

英

Pseudo-Pelger-Huet anomaly

同

偽Pelger-Huet核異常

関

ペルゲル・フェット核異常

• 低分葉核好中球であり、骨髄異形成症候群でみられる。また、抗悪性腫瘍薬の使用でもみられるらしい(参考2)

参考

• 1. 不応性貧血(骨髄異形成症候群)診療の参照ガイド

http://www.jichi.ac.jp/zoketsushogaihan/MDS.doc

• 2. タキソイド系抗悪性腫瘍剤使用後に見られた好中球の形態異常

http://www.tsuboi-hp.or.jp/main/HTML/PART/kensaHP/kensabu_study/0005web/takisoid2.htm

「anomaly」

　　[★]

• n.

• 異常、変則。異形。

関

aberrant、aberrantly、aberration、abnormal、abnormality、abnormally、anomalous、anomalously、defect、deviant、exceeding、exception、exceptional、extraordinarily、extraordinary、unusual、unusually

　 　 　 　

「pseudo」

　　[★]

• n.

• 仮性、偽性、ニセ

関

counterfeit、false、mock、sham、spurious