出典: meddic

A-kinasecAMP-dependent protein kinasecyclic AMP-dependent protein kinaseprotein kinase A
See Protein kinase A
Protein kinase A

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/07/09 17:15:51」(JST)

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  • Integrating fluorescent biosensor data using computational models.
  • Greenwald EC, Polanowska-Grabowska RK, Saucerman JJ.SourceDepartment of Biomedical Engineering, University of Virginia, Charlottesville, VA, USA.
  • Methods in molecular biology (Clifton, N.J.).Methods Mol Biol.2014;1071:227-48. doi: 10.1007/978-1-62703-622-1_18.
  • This book chapter provides a tutorial on how to construct computational models of signaling networks for the integration and interpretation of FRET-based biosensor data. A model of cAMP production and PKA activation is presented to provide an example of the model building process. The computational
  • PMID 24052393
  • A Multiparameter Live Cell Imaging Approach to Monitor Cyclic AMP and Protein Kinase A Dynamics in Parallel.
  • Aye-Han NN, Zhang J.SourceDepartment of Pharmacology and Molecular Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Methods in molecular biology (Clifton, N.J.).Methods Mol Biol.2014;1071:207-15. doi: 10.1007/978-1-62703-622-1_16.
  • Parallel detection of signaling activities allows us to correlate activity dynamics between signaling molecules. In this review, we detail a multiparameter live cell imaging method to monitor 3',5'-cyclic adenosine monophosphate (cAMP) levels and protein kinase A (PKA) activities in parallel.
  • PMID 24052391
  • Biosensor imaging in brain slice preparations.
  • Polito M, Vincent P, Guiot E.SourceCentre National de la Recherche Scientifique, Unité Mixe de Recherche and Université Pierre et Marie Curie, Paris, France.
  • Methods in molecular biology (Clifton, N.J.).Methods Mol Biol.2014;1071:175-94. doi: 10.1007/978-1-62703-622-1_14.
  • Cyclic-AMP dependent protein kinase (PKA) is present in most branches of the animal kingdom, and is an example in the nervous system where a kinase effector integrates the cellular effects of various neuromodulators. The recent development of FRET-based biosensors, such as AKAR, now allows the direc
  • PMID 24052389


  • A Simple Method of Evaluating Alkanolamine Absorbents for Post-Combustion CO₂ Capture
  • GOTO Kazuya,YAMADA Hidetaka,HIGASHII Takayuki
  • Journal of chemical engineering of Japan 47(4-7), 463-470, 2014-07
  • NAID 40020131979
  • In vivo imaging reveals PKA regulation of ERK activity during neutrophil recruitment to inflamed intestines.
  • Mizuno Rei,Kamioka Yuji,Kabashima Kenji,Imajo Masamichi,Sumiyama Kenta,Nakasho Eiji,Ito Takeshi,Hamazaki Yoko,Okuchi Yoshihisa,Sakai Yoshiharu,Kiyokawa Etsuko,Matsuda Michiyuki
  • The Journal of experimental medicine, 2014-05-19
  • … Here, by in vivo two-photon excitation microscopy with transgenic mice expressing biosensors based on Förster resonance energy transfer, we time-lapse-imaged the activities of extracellular signal-regulated kinase (ERK) and protein kinase A (PKA) in neutrophils in inflamed intestinal tissue. … Meanwhile, in the neutrophils migrating in the interstitial tissue, high PKA activity correlated negatively with migration velocity. …
  • NAID 120005439165
  • グルカゴン受容体とその作用 (特集 グルカゴンの分泌調節と作用)
  • 細岡 哲也,小川 渉
  • 内分泌・糖尿病・代謝内科 38(5), 403-409, 2014-05
  • NAID 40020124795


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 of Acid-Base reactions (4) – pKa of Acid-Base reactions (4) – pKa Role of PKA in cytoskeleton reorganisation HA], log 10 = 0 and the pH = pKacamp pka signaling pathway pka pKa

先読みcyclic AMP-dependent protein kinase
リンク元ホスホランバン」「サイクリックAMP依存性タンパク質キナーゼ」「cAMP-dependent protein kinase」「プロテインキナーゼA」「A-kinase

cyclic AMP-dependent protein kinase」

  [★] プロテインキナーゼA

See Protein kinases




  • M.W.:6.0kDa
  • 5量体を形成。心筋の小胞体の膜上に存在。
  • 小胞体のCa2+輸送制御タンパク質である。小胞体のCaポンプに結合して小胞体へのCaへの取り込みを阻害している。PKAによりリン酸化を受けるとこの抑制が解除され、小胞体へのCa2+取り込みが促進される。これにより心筋の陽性変力作用を呈する (SPC.222)



cyclic AMP-dependent protein kinasecAMP-dependent protein kinaseprotein kinase APKA

cAMP-dependent protein kinase」


A-kinasecyclic AMP-dependent protein kinasePKAprotein kinase A



protein kinase A PKA
Aキナーゼ A kinaseサイクリックAMP依存性プロテインキナーゼ cyclic AMP-dependent protein kinase
プロテインキナーゼ protein kinase




cAMP-dependent protein kinasePKAprotein kinase A



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