Leydig cell

出典: meddic


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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/08/09 23:28:15」(JST)

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  • Testicular expression of SP-A, SP-D and MBL-A is positively regulated by testosterone and modulated by lipopolysaccharide.
  • Rokade S1, Madan T2.
  • Immunobiology.Immunobiology.2016 Sep;221(9):975-85. doi: 10.1016/j.imbio.2016.05.005. Epub 2016 May 24.
  • Pattern recognition proteins viz., Surfactant Protein-A (SP-A), Surfactant Protein-D (SP-D) and Mannan Binding Lectin-A (MBL-A) regulate inflammatory immune responses. In view of their plausible contribution to immune privilege in testis, the present study explored their expression and regulation in
  • PMID 27262512
  • Di-(2-ethylhexyl) phthalate inhibits testosterone level through disturbed hypothalamic-pituitary-testis axis and ERK-mediated 5α-Reductase 2.
  • Ha M1, Guan X2, Wei L2, Li P3, Yang M2, Liu C4.
  • The Science of the total environment.Sci Total Environ.2016 Sep 1;563-564:566-75. doi: 10.1016/j.scitotenv.2016.04.145. Epub 2016 May 4.
  • Di-(2-ethylhexyl) phthalate (DEHP) has reproductive toxicity and can affect male reproductive development. In order to clarify adverse effects of DEHP on testicular physiology and testosterone production, Sprague-Dawley (SD) rats were dosed daily with DEHP by gavage for 30days; TM3 cells (mouse Leyd
  • PMID 27155079
  • Expression analysis and localization of wt1, ad4bp/sf-1 and gata4 in the testis of catfish, Clarias batrachus: Impact of wt1-esiRNA silencing.
  • Murugananthkumar R1, Senthilkumaran B2.
  • Molecular and cellular endocrinology.Mol Cell Endocrinol.2016 Aug 15;431:164-76. doi: 10.1016/j.mce.2016.05.006. Epub 2016 May 10.
  • In teleosts, a comprehensive role or interaction of wt1, ad4bp/sf-1 and gata4 genes in relation to gonadal development and/or recrudescence was never attempted. Present study aimed to identify the involvement of these genes during testicular development of catfish, Clarias batrachus. Dominant expres
  • PMID 27173028


  • 高齢者に見られた精巣Leydig細胞腫の1例
  • 田口 慧,山口 千美,高橋 さゆり [他]
  • 泌尿器科紀要 57(9), 521-524, 2011-09
  • … Histopathological diagnosis was Leydig cell tumor. …
  • NAID 40018993727
  • Research on the Isolation of Mouse Leydig Cells Using Differential Digestion with a Low Concentration of Collagenase
  • SUN Jie,ZHONG Liang,ZHU Yingjian,LIU Guohua
  • The Journal of reproduction and development 57(3), 433-436, 2011-06-01
  • … The aim of this study was to establish a novel method for isolating and purifying Leydig cells from mice testes. … Immunofluorescence was used to detect the expression of Leydig cell biomarkers including 3β-hydroxysteroid dehydrogenase, cholesterol side-chain cleaving enzyme (CYP11A1) and 17α-hydroxylase/17,20-lyase (CYP17A1). … It was found that the purity of the isolated Leydig cells was 69.6 ± 4.16%. …
  • NAID 10029050947


Leydig cell tumors are rare testicular tumors of the male gonadal interstitium that may be hormonally active and lead to feminizing or virilizing syndromes. Radical orchiectomy was once the primary treatment for Leydig cell tumors, and it remains in use for malignant cases. However, testis ...
Leydig cell n. See interstitial cell. Leydig cell Leydig cell The testosterone-secreting cell of the testis which is located in clusters in the interstitium between the seminiferous tubules. Leydig cells are large and have centrally located ...



拡張検索Sertoli-Leydig cell tumor」「Sertoli-Leydig cell tumors」「Leydig cell tumors



gyneco mastia

病因 (HIM.2318)

  • 1. アンドロゲンの不足→↑estrogen/androgen ratio→女性化乳房
  • 2. アンドロゲンの不応症?(angrogen insensitivity disorgers
  • 3. エストロゲンの過剰産生
  • including Sertoli cell tumors in isolation or in association with Peutz-Jegher syndrome or Carney complex
  • tumors that produce hCG, including some testicular tumors, stimulate Leydig cell estrogen synthesis.
  • 4. アロマターゼの基質の増加:アンドロステンジオンの増加
  • 5. アロマターゼ活性の亢進:肥満
  • 肥満
  • 肝臓や副腎の腫瘍


SPE.11 QB.O-27 101B080
  • 男性でも13-14歳際頃に乳腺の肥大、乳房の腫大、腫大部の疼痛を認める



Leydig cell (Z)
Leydig細胞間質細胞 interstitial cell間質腺 interstitial gland
精巣間質細胞 睾丸間質細胞 interstitial cell of the testis stromal cell of the testis


  • 由来:生殖堤の元の間葉(L.305)


Sertoli-Leydig cell tumor」

  [★] セルトリ・ライディッヒ細胞腫

Sertoli-Leydig cell tumors」

  [★] セルトリ・ライディッヒ細胞腫

Leydig cell tumors」

  [★] ライディッヒ細胞腫


  [★] 細胞

WordNet   license wordnet

「small room in which a monk or nun lives」

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「a device that delivers an electric current as the result of a chemical reaction」
electric cell

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「a room where a prisoner is kept」
jail cell, prison cell

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「(biology) the basic structural and functional unit of all organisms; they may exist as independent units of life (as in monads) or may form colonies or tissues as in higher plants and animals」

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「any small compartment; "the cells of a honeycomb"」

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「a small unit serving as part of or as the nucleus of a larger political movement」

PrepTutorEJDIC   license prepejdic

「(刑務所の)『独房』;(修道院の)小さい独居室 / (ミツバチの)みつ房,巣穴 / 小さい部屋 / 『細胞』 / 電池 / 花粉室 / (共産党などの)細胞」