Eph family receptor

出典: meddic


Eph receptorEph receptor tyrosine kinaseEphA receptorEphB receptorephrin receptor

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  • Ephrin reverse signaling mediates palatal fusion and epithelial-to-mesenchymal transition independently of tgfß3.
  • Serrano MJ1, Liu J2, Svoboda KK1, Nawshad A2, Benson MD1.
  • Journal of cellular physiology.J Cell Physiol.2015 Dec;230(12):2961-72. doi: 10.1002/jcp.25025.
  • The mammalian secondary palate forms from shelves of epithelia-covered mesenchyme that meet at midline and fuse. The midline epithelial seam (MES) is thought to degrade by apoptosis, epithelial-to-mesenchymal transition (EMT), or both. Failure to degrade the MES blocks fusion and causes cleft palate
  • PMID 25893671
  • The receptor tyrosine kinase EphB2 promotes hepatic fibrosis in mice.
  • Mimche PN1, Brady LM1, Bray CF1, Lee CM2, Thapa M3, King TP1, Quicke K1, McDermott CD1, Mimche SM2, Grakoui A3, Morgan ET2, Lamb TJ1.
  • Hepatology (Baltimore, Md.).Hepatology.2015 Sep;62(3):900-14. doi: 10.1002/hep.27792. Epub 2015 Apr 22.
  • Beyond the well-defined role of the Eph (erythropoietin-producing hepatocellular) receptor tyrosine kinases in developmental processes, cell motility, cell trafficking/adhesion, and cancer, nothing is known about their involvement in liver pathologies. During blood-stage rodent malaria infection we
  • PMID 25784101
  • EphA2 expression is a key driver of migration and invasion and a poor prognostic marker in colorectal cancer.
  • Dunne PD1, Dasgupta S2, Blayney J3, McArt DG4, Redmond KL5, Weir JA6, Bradley CA6, Sasazuki T7, Shirasawa S8, Wang T9, Srivastava S10, Ong CW1, Arthur K11, Salto-Tellez M12, Wilson RH13, Johnston PG6, Van Schaeybroeck S14.
  • Clinical cancer research : an official journal of the American Association for Cancer Research.Clin Cancer Res.2015 Aug 17. pii: clincanres.0603.2015. [Epub ahead of print]
  • PURPOSE: EphA2, a member of the Eph receptor tyrosine kinases family, is an important regulator of tumour initiation, neo-vascularization and metastasis in a wide range of epithelial and mesenchymal cancers, however its role in colorectal cancer (CRC) recurrence and progression is unclear.EXPERIMENT
  • PMID 26283684


  • Localization of Ebk/MDK1 in Mouse Oral Development
  • Shimizu Takehiko,Maeda Takahide
  • 歯科基礎医学会雑誌 45(2), 52-58, 2003-04-20
  • NAID 110003166806
  • A Novel Truncated Variant Form of Ebk/MDK1 Receptor Tyrosine Kinase Is Expressed in Embryonic Mouse Brain
  • Talukder Amjad H.,Muramatsu Takashi,Kaneda Norio
  • Cell structure and function 22(4), 477-485, 1997-08-00
  • NAID 10001917899
  • Dynamic expression suggests multiple roles of the eph family receptor brain-specific kinase (Bsk) during mouse neurogenesis


Of the 16 Eph receptors (see above) that have been identified in animals, humans are known to express nine EphAs (EphA1-8 and EphA10) and five EphBs .... "Unified nomenclature for Eph family receptors and their ligands, the ephrins".
The Eph family of receptors is the largest known subfamily of receptor tyrosine kinases.1,2 The ligands are called ephrins. The ephrin-Eph interactions are important in development, especially in cell-cell interactions involved in nervous system ...



リンク元Eph receptor」「Eph receptor tyrosine kinase」「ephrin receptor」「EphA receptor」「EphB receptor

Eph receptor」



Eph family receptorEph receptor tyrosine kinaseEphA receptorEphA1 receptorEphB receptorephrin receptor

Eph receptor tyrosine kinase」


Eph family receptorEph receptorEphA receptorEphB receptorephrin receptor

ephrin receptor」


Eph family receptorEph receptorEph receptor tyrosine kinaseEphA receptorEphB receptor

EphA receptor」



Eph family receptorEph receptorEph receptor tyrosine kinaseEphB receptorephrin receptor

EphB receptor」



Eph family receptorEph receptorEph receptor tyrosine kinaseEphA receptorephrin receptor



  • n.

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「people descended from a common ancestor; "his family has lived in Massachusetts since the Mayflower"」
family line, folk, kinfolk, kinsfolk, sept, phratry

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「primary social group; parents and children; "he wanted to have a good job before starting a family"」
family unit

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「an association of people who share common beliefs or activities; "the message was addressed not just to employees but to every member of the company family"; "the church welcomed new members into its fellowship"」

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「a social unit living together; "he moved his family to Virginia"; "It was a good Christian household"; "I waited until the whole house was asleep"; "the teacher asked how many people made up his home"」
household, house, home, menage

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「(biology) a taxonomic group containing one or more genera; "sharks belong to the fish family"」

PrepTutorEJDIC   license prepejdic

「《集合的に》『家族』,家庭 / 〈U〉《時にa family》(一家の)子供たち / 〈C〉(血縁に関係ある)『親族』,身内,一族,一門 / 〈U〉『家柄』;(特に)名門 / 〈C〉(関係ある人・物の)一団,一群,(生物分類の)科《+『of』+『名』》」


  [★] 受容体

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「a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response」

PrepTutorEJDIC   license prepejdic

「=sense organ / 受信装置」



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「the 5th letter of the Roman alphabet」


  [★] エリスロポエチン