関: Eph family receptor、Eph receptor、Eph receptor tyrosine kinase、EphB receptor、ephrin receptor

WordNet

a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response

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EphA receptors regulate prostate cancer cell dissemination through Vav2-RhoA mediated cell-cell repulsion.

Batson J1, Maccarthy-Morrogh L, Archer A, Tanton H, Nobes CD.
Biology open.Biol Open.2014 May 2. pii: bio.20146601v1. doi: 10.1242/bio.20146601. [Epub ahead of print]
Metastatic prostate cancer cells display EphB receptor-mediated attraction when they contact stromal fibroblasts but EphA-driven repulsion when they contact one another. The impact of these 'social' interactions between cells during cancer cell invasion and the signalling mechanisms downstream of Ep
PMID 24795148

Cell segregation in the vertebrate hindbrain relies on actomyosin cables located at the interhombomeric boundaries.

Calzolari S1, Terriente J, Pujades C.
The EMBO journal.EMBO J.2014 Apr 1;33(7):686-701. doi: 10.1002/embj.201386003. Epub 2014 Feb 25.
Segregating cells into compartments during embryonic development is essential for growth and pattern formation. Physical mechanisms shaping compartment boundaries were recently explored in Drosophila, where actomyosin-based barriers were revealed to be important for keeping cells apart. In vertebrat
PMID 24569501

Sizes of interface residues account for cross-class binding affinity patterns in Eph receptor-ephrin families.

Guo FY1, Lesk AM.
Proteins.Proteins.2014 Mar;82(3):349-53. doi: 10.1002/prot.24414. Epub 2013 Oct 18.
Eph receptors comprise the largest known family of receptor tyrosine kinases in mammals. They bind members of a second family, the ephrins. As both Eph receptors and ephrins are membrane bound, interactions permit unusual bidirectional cell-cell signaling. Eph receptors and ephrins each form two cla
PMID 24105818

Gene Expression Profiling and Cellular Distribution of Molecules with Altered Expression in the Hippocampal CA1 Region after Developmental Exposure to Anti-Thyroid Agents in Rats

SAEGUSA Yukie,WOO Gye-Hyeong,FUJIMOTO Hitoshi,INOUE Kaoru,TAKAHASHI Miwa,HIROSE Masao,IGARASHI Katsuhide,KANNO Jun,MITSUMORI Kunitoshi,NISHIKAWA Akiyoshi,SHIBUTANI Makoto
Journal of Veterinary Medical Science advpub(0), 0911180044, 2010
… We, then, examined immunohistochemical cellular distribution of Ephrin type A receptor 5 (EphA5) and Tachykinin receptor (Tacr)-3, those selected based on the gene expression profiles, in the hippocampal formation at the adult stage (11-week-old) as well as at the end of exposure. … At weaning, both EphA5- and Tacr3-immunoreactive cells with strong intensities appeared in the pyramidal cell layer or stratum oriens of the hippocampal CA1 region. …
NAID 130000134528

EphA4 receptor, overexpressed in pancreatic ductal adenocarcinoma, promotes cancer cell growth

IIIZUMI Megumi,HOSOKAWA Masayo,TAKEHARA Akio,CHUNG Suyoun,NAKAMURA Toru,KATAGIRI Toyomasa,EGUCHI Hidetoshi,OHIGASHI Hiroaki,ISHIKAWA Osamu,NAKAMURA Yusuke,NAKAGAWA Hidewaki
Cancer science 97(11), 1211-1216, 2006-11-10
NAID 10019377141