関: Eph family receptor、Eph receptor、Eph receptor tyrosine kinase、EphA receptor、ephrin receptor

WordNet

a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response

PrepTutorEJDIC

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

Activation of ephrinB-EphB receptor signalling in rat spinal cord contributes to maintenance of diabetic neuropathic pain.

Deng XT1, Wu MZ2, Xu N2, Ma PC1, Song XJ1,2.
European journal of pain (London, England).Eur J Pain.2017 Feb;21(2):278-288. doi: 10.1002/ejp.922. Epub 2016 Jul 27.
BACKGROUND: Diabetic neuropathic pain (DNP) is severe and intractable in clinic. The specific cellular and molecular mechanisms underlying DNP remain elusive and its treatment are limited. We investigated roles of EphB1 receptor in the development of DNP.METHODS: Diabetic neuropathic pain was produc
PMID 27461472

Somatic ephrin receptor mutations are associated with metastasis in primary colorectal cancer.

Mathot L1, Kundu S1, Ljungström V2, Svedlund J3, Moens L2, Adlerteg T2, Falk-Sörqvist E2, Rendo V4, Bellomo C5, Mayrhofer M6, Cortina C7, Sundström M8, Micke P9, Botling J10, Isaksson A6, Moustakas A11, Batlle E12, Birgisson H13, Glimelius B14, Nilsson M15, Sjöblom T16.
Cancer research.Cancer Res.2017 Jan 20. pii: canres.1921.2016. doi: 10.1158/0008-5472.CAN-16-1921. [Epub ahead of print]
The contribution of somatic mutations to metastasis of colorectal cancers (CRC) is currently unknown. To find mutations involved in the CRC metastatic process, we performed deep mutational analysis of 676 genes in 107 stages II-IV primary CRC, of which half had metastasized. The mutation prevalence
PMID 28108514

EphB3 Stimulates Cell Migration and Metastasis in a Kinase-dependent Manner through Vav2-Rho GTPase Axis in Papillary Thyroid Cancer.

Li JJ1, Sun ZJ1, Yuan YM1, Yin FF1, Bian YG2, Long LY1, Zhang XL3, Xie D4.
The Journal of biological chemistry.J Biol Chem.2017 Jan 20;292(3):1112-1121. doi: 10.1074/jbc.M116.750349. Epub 2016 Dec 16.
Eph receptors, the largest subfamily of transmembrane tyrosine kinase receptors, have been increasingly implicated in various physiologic and pathologic processes, and the roles of the Eph family members during tumorigenesis have recently attracted growing attentions. In the present study, we explor
PMID 27986811