WordNet

the 15th letter of the Roman alphabet (同)o
the blood group whose red cells carry neither the A nor B antigens; "people with type O blood are universal donors" (同)type_O, group O

PrepTutorEJDIC

《呼び掛けの名前の前につけて》『おお』,あ / (驚き・恐れ・喜び・苦痛などを表して)『おお』,ああ,まあ / 《肯定・否定を強めて》
oxygenの化学記号
ohmオーム / Old
Ohio

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1. ダウン症候群およびトリソミー18のスクリーニングのための、妊娠初期のcombined testおよびintegrated testfirst trimester combined test and integrated tests for screening for down syndrome and trisomy 18 [show details]
…detected 90 percent of trisomy 18 pregnancies at a FPR of 0.1 percent . The risk of a trisomy 18 pregnancy among screen-positive women was 1 in 4. The addition of NT to a trisomy 18 screening algorithm will …
2. 18か月未満の乳幼児へのＨＩＶ感染診断テストdiagnostic testing for hiv infection in infants and children younger than 18 months [show details]
…to 18 months of age to document clearance of maternal antibody and confirm the child HIV-negative status . The diagnosis of HIV infection in children with perinatal exposure who are older than 18 months …
3. 7～18歳の小児におけるジフテリア、破傷風、および百日咳ワクチンdiphtheria tetanus and pertussis immunization in children 7 through 18 years of age [show details]
… Diphtheria, tetanus, and pertussis immunization in children and adolescents 7 through 18 years of age will be discussed here. Diphtheria, tetanus, and pertussis immunization in children six weeks through …
4. 原発性高シュウ酸尿症primary hyperoxaluria [show details]
…those with type 1 disease (four patients at 10 years compared with none of those with type 2 disease at 18 years), which may have been due in part to significantly higher urinary oxalate excretion rates. In … Hyperoxaluria Foundation; 201 East 19^th Street, Suite 12E New York, NY 10003 212-777-0470 email: OHF@OHFUltranet.com Clinicians: OxalEurope ; University College London Hospitals primary hyperoxaluria…
5. 胎児異数性に関連する超音波所見sonographic findings associated with fetal aneuploidy [show details]
…(LR for trisomy 21: 52 versus 18), and at NT 3.5-4.4 mm versus NT ≥5.5 mm (LR for trisomy 21: 13 versus 5) . An absent nasal bone is less common in fetuses with trisomy 18 or 13 than in those with Down …

English Journal

Tandem Mass Spectrometry Imaging Reveals Distinct Accumulation Patterns of Steroid Structural Isomers in Human Adrenal Glands.

Takeo E, Sugiura Y, Uemura T, Nishimoto K, Yasuda M, Sugiyama E, Ohtsuki S, Higashi T, Nishikawa T, Suematsu M, Fukusaki E, Shimma S.
Analytical chemistry. 2019 Jul;91(14)8918-8925.
Visualizing tissue distribution of steroid hormones is a promising application of MALDI mass spectrometry imaging (MSI). On-tissue chemical derivatization using Girard's T reagent has enhanced the ionization efficiency of steroids. However, discriminating between structural isomers with distinct bio
PMID 31204806

Diagnosis of glucocorticoid-remediable aldosteronism in hypertensive children.

Kamrath C, Maser-Gluth C, Haag C, Schulze E.
Hormone research in paediatrics. 2011 ;76(2)93-8.
Glucocorticoid-remediable aldosteronism (GRA) is caused by the presence of a chimeric gene originating from an unequal cross-over between the CYP11B1 and CYP11B2 genes. Aldosterone suppression by dexamethasone and high 18-hydroxycortisol (18-OHF) levels have been used to differentiate GRA from the o
PMID 21625068

Endogenous corticosteroid biosynthesis in subjects after bilateral adrenalectomy.

Freel EM, Bernhardt R, Bernhardt M, Ingram M, Ingram R, Wallace AM, Fraser R, Davies E, Connell JM.
Clinical endocrinology. 2007 May;66(5)659-65.
Corticosteroids can be synthesized in extra-adrenal tissues but the contribution of this to circulating levels in humans is not known. Previous in vitro studies suggest that the 'hybrid' corticosteroid 18-oxocortisol (18-oxoF) is produced from cortisol by aldosterone synthase. We looked for evidence
PMID 17381495

Japanese Journal

ハイブリッドステロイド質量分析による原発性アルドステロン症の鑑別診断 (第60回学術集会シンポジウム2 タンデム型質量分析計による臨床サンプルの定量分析)

和田典男,神繁樹,惠淑萍 [他]
臨床病理 : 日本臨床検査医学会誌 62(3), 276-282, 2014-03
NAID 40020057177

「18-ヒドロキシコルチゾール」

　　[★]

英: 18-hydroxycortisol
同: 18-OHF

1982年、チュア(Chu MD)とユーリック(Ulick S)らにより原発性アルドステロン症患者の尿中より検出された17α-水酸基と18-水酸基の双方を有するステロイド。
18-OHFと略記される。
OHはヒドロオキシを示し、Fはケンドールの命名法のcompound Fによる。
糖質コルチコイドと鉱質コルチコイドの両方の特徴をもつためハイブリッドステロイド(hybrid steroid)と呼ばれ、原発性アルドステロン症と糖質コルチコイド反応性アルドステロン症のマーカーとして臨床応用される。