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- 1. 内因性および外因性ステロイドの尿中排泄の測定measurement of urinary excretion of endogenous and exogenous glucocorticoids [show details]
…17-hydroxycorticosteroids (17-OHCS) are tetrahydro metabolites of cortisol and cortisone (THF and THE), but THS, the tetrahydro metabolite of 11-deoxycortisol, also is present. As a result, 17-OHCS excretion roughly …
- 2. 血清および唾液中のコルチゾールの測定measurement of cortisol in serum and saliva [show details]
…chromatography (TLC). This assay exploits the fluorescence of 4-11-beta, 21-dihydroxy-3,20-ketosteroids (11-hydroxycorticosteroids, or 11-OHCS) in sulfuric acid and alcohol . Cortisol and corticosterone are …
- 3. メチラポン刺激試験metyrapone stimulation tests [show details]
…clinical laboratories that routinely perform urinary 17-hydroxycorticosteroid (17-OHCS) testing. The measurement of serum 11-deoxycortisol performed by liquid chromatography with tandem mass spectrometry …
- 4. 副腎酵素阻害剤および抗アドレナリン薬の薬理および毒性pharmacology and toxicity of adrenal enzyme inhibitors and adrenolytic agents [show details]
… Metyrapone is mainly an inhibitor of CYP11B1 (11-beta-hydroxylase), which catalyzes the final step in cortisol biosynthesis, conversion of 11-deoxycortisol to cortisol .… in the 17-OHCS assay. This is important clinically because the efficacy of mitotane therapy should be assessed by measuring 24-hour urinary free cortisol excretion, not urinary 17-OHCS excretion,…
- 5. 微細欠失症候群（1番～11番染色体）microdeletion syndromes chromosomes 1 to 11 [show details]
…some cases, a single gene. This topic reviews microdeletion syndromes involving chromosomes 1 through 11. Microdeletion syndromes involving chromosomes 12 through 22 are discussed separately, as are microduplication …
English Journal
- [11-Hydroxycorticoid (11-OHCS)].
- Yamada Y, Sekihara H.
- Nihon rinsho. Japanese journal of clinical medicine. 2005 Aug;63 Suppl 8()358-60.
- PMID 16149529
- [11-hydroxycorticosteroid (11-OHCS)].
- Aoki K, Sekihara H.
- Nihon rinsho. Japanese journal of clinical medicine. 1999 Dec;57 Suppl()188-90.
- PMID 10778096
- Secretory function of adrenal cortex in chronic alcoholis.
- , F F, I I, I I, .
- Medicinski pregled. ;52(6-8)221-5.
- Three groups of male subjects (healthy subjects, chronic alcoholics with liver cirrhosis and patients with acute viral hepatitis) were included in a 24 hour pattern of excretion of the total and some fractions of 17-ketosteroids (KS), basal concentration of 11-hydroxycorticosteroids (11-OHCS) and de
- PMID 10518376
Japanese Journal
- 11-ヒドロキシコルチコイド(11-OHCS),17-ヒドロキシコルチコイド(17-OHCS) (広範囲 血液・尿化学検査 免疫学的検査(第7版・4)その数値をどう読むか) -- (内分泌学的検査 副腎皮質関係)
- 道路輸送に対するサラブレッド馬のストレス反応,特に輸送熱に関して
- 及川 正明,高木 茂美,屋鋪 和成
- Journal of equine science = Continuation of Japanese Journal of Equine Science and Bulletin of Equine Research Institute 15(4), 99-102, 2004-12-01
- … In both sets of experiments, "affected" horses showed a significantly greater increase or decrease in levels of the indices of the stress response, i.e., eosinophil count, erythrocyte sedimentation rate, levels of serum glucose, adrenocorticotropic hormone (ACTH) and 11-hydroxycorticosteroid (11-OHCS) than "unaffected" horses after road transportation. …
- NAID 10014368859
- Beclomethasone dipropionate (BDP) 吸入療法施行中の喘息患児における副腎皮質機能の検討
- 阿部 裕樹,上原 由美子,阿部 時也
- 日本小児アレルギー学会誌 13(2), 38-43, 1999
- … そこで我々は, 当科にてBDP療法中の16名 (男子11名女子5名, 年齢: 12.7±2.8歳 [mean±SD], 吸入期間: 648.1±206.0日, 吸入量: 12.1±5.4μg/kg/day) で, コルチゾール日内変動, 尿中17-OHCS測定, rapid ACTH 試験による副腎皮質機能の検討をBDP導入前後に行った. …
- NAID 130004370564
Related Links
- 血中11-OHCSのページです。副腎皮質で産生される糖質ホルモンの大部分はコルチゾールであるが，そのほかに少量のコルチコステロンもあり，それらの分泌量は脳下垂体ACTHによって調節されている。両者ともにステロイド核の11位にOH基 ...
- 11-OHCS、臨床的意義や基準値・異常値について。シスメックスは検体検査を通じて、疾病の早期発見や早期治療に貢献していくとともに、プライマリケアや診療支援に有用な情報を提供するサイトです。
- 17-OHCSとは何か OHCSとはhydroxycorticosteroidの略。-OHとは水酸基を意味しているので水酸化されたコルチコステロイドと考えるとわかりやすい。 臨床においては尿中17OHCSを測定する。血中の値を測定したほうが簡便な気もするが ...
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眼圧亢進、ocular hypertension
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ヒドロキシコルチコステロイド