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- xanthinol niacinate
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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/05/26 11:15:26」(JST)
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Xantinol nicotinate
Combination of |
Xanthinol |
vasodilator |
Clinical data |
AHFS/Drugs.com |
International Drug Names |
Routes of
administration
|
Oral |
Identifiers |
CAS Registry Number
|
Y |
ATC code
|
C04AD02 |
PubChem |
CID 9912 |
UNII |
8G60H12X2D N |
KEGG |
D06334 Y |
N (what is this?) (verify) |
Xantinol nicotinate (or xanthinol niacinate) is a vasodilator. It is a combination of xanthinol and niacin (nicotinic acid).[1]
References
- ^ Xanthinol niacinate at cancerweb.ncl.ac.uk
Peripheral vasodilators (C04)
|
|
Phenylethanolamine derivatives |
- Isoxsuprine
- Buphenine
- Bamethan
|
|
Imidazoline derivatives/
Alpha blockers |
|
|
Niacin and derivatives |
- Niacin
- Nicotinyl alcohol
- Inositol nicotinate
- Ciclonicate
|
|
Purine derivatives |
- Pentifylline
- Xantinol nicotinate
- Pentoxifylline
- Etofylline nicotinate
|
|
Ergot alkaloids |
- Ergoloid
- Nicergoline
- Dihydroergocristine
|
|
Other peripheral vasodilators |
- Cyclandelate
- Phenoxybenzamine
- Vincamine
- Moxisylyte
- Bencyclane
- Vinburnine
- Sulcotidil
- Buflomedil
- Naftidrofuryl
- Butalamine
- Visnadine
- Cetiedil
- Cinepazide
- Ifenprodil
- Azapetine
- Fasudil
|
|
Index of the circulatory system
|
|
Description |
- Anatomy
- Arteries
- head and neck
- arms
- chest
- abdomen
- legs
- Veins
- head and neck
- arms
- chest
- abdomen and pelvis
- legs
- Development
- Cells
- Physiology
|
|
Disease |
- Congenital
- Neoplasms and cancer
- Lymphatic vessels
- Injury
- Vasculitis
- Other
- Symptoms and signs
|
|
Treatment |
- Procedures
- Drugs
- beta blockers
- channel blockers
- diuretics
- nonsympatholytic vasodilatory antihypertensives
- peripheral vasodilators
- renin–angiotensin system
- sympatholytic antihypertensives
- vasoprotectives
|
|
|
It is a compound of xanthine and nicotinic acid, both of which are vasodilators. It increases blood flow in many vascular beds andhas been promoted for cerebrovascular disorders and PVDs, but therapeutic benefits are insignificant.
UpToDate Contents
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English Journal
- [Role of low-dose acetylsalicylic acid in comprehensive postoperative treatment of patients with lower-limb chronic arterial insufficiency].
- Kuznetsov MR, Rodionov SV, Koshkin VM, Virganskiĭ AO, Golosnitskiĭ PIu, Tepliakov SA, Kosykh IV, Ostapchuk NA, Lisenkov OP, Chernikov VP.AbstractThe study comprised a total of 107 patients (all men) after endured femoropopliteal bypass grafting above the genicular fissure with a synthetic stent graft manufactured by the Gore Company for stage IIB and III chronic arterial insufficiency of the lower extremities according to the Fontain-Pokrovsky classification. Group One I (control group) was composed of fifty-four patients permanently taking in the postoperative period at the out-patient stage pentoxiphylline (trental 400 mg 1 tablet 3 times daily) and xantinol nicotinate at a dose of 150 mg one tablet thrice daily. Group Two (Study Group) consisted of fifty-three patients taking after reconstructive vascular surgery at the out-patient stage in addition to pentoxiphylline and xantinol nicotinate acetylsalicylic acid (cardiomagnil 75 mg 1 tablet once daily). The Control Group patients within 3 to 6 months of follow up were found to have a considerable progressing improvement of the functional abilities of the microcirculatory bed requiring in 44 (81.5%) cases hospitalization to the Surgical Department for intensive vascular therapy. Despite this fact four (7.4%) patients within the time frame from 6 to 9 months after surgery developed thrombosis of the vascular implant requiring a repeat surgical intervention. In the Study Group patients, the degree of functional capabilities of the microcirculatory bed in the postoperative period was less considerable, reaching the maximum after 10-12 months of follow up, with eighteen (34.0%) patients requiring hospitalization for additional vascular therapy to perform. There were no cases of implants' thrombosis in the Study Group patients. Pathological alterations in the functional state of the peripheral vascular bed correlated with viscosimetric indices and activity of blood platelet aggregation. The addition of antithrombocytic agents to conservative postoperative therapy considerably improved the outcomes of surgical treatment.
- Angiologii͡a i sosudistai͡a khirurgii͡a = Angiology and vascular surgery.Angiol Sosud Khir.2011;17(2):23-9.
- The study comprised a total of 107 patients (all men) after endured femoropopliteal bypass grafting above the genicular fissure with a synthetic stent graft manufactured by the Gore Company for stage IIB and III chronic arterial insufficiency of the lower extremities according to the Fontain-Pokrovs
- PMID 21983458
- [Peyronie's disease: comparative results of conservative treatment].
- Kovalev VA, Karaguzhin SK, Abdulkhamidov AN, Danovich VM, Kyzlasov PS, Matskevich SV.AbstractLong-term clinical experience with conservative treatment of Peyronie's disease has demonstrated that clinical efficacy of this therapy comprises maily anesthesia while erectile problems are not solved. Introduction of the drugs into the fibrous plaque is not adequate and hard to perform. Some drugs affect only some components of pathogenesis. For stabilization of the process it is recommended to use transdermal electrophoresis or phonophoresis. The search for new effective drugs and methods continues.
- Urologii͡a (Moscow, Russia : 1999).Urologiia.2010 Nov-Dec;(6):40-4.
- Long-term clinical experience with conservative treatment of Peyronie's disease has demonstrated that clinical efficacy of this therapy comprises maily anesthesia while erectile problems are not solved. Introduction of the drugs into the fibrous plaque is not adequate and hard to perform. Some drugs
- PMID 21427993
Related Links
- Xantinol Nicotinate is a medicine available in a number of countries worldwide. A list of US medications equivalent to Xantinol Nicotinate is available on the Drugs.com website. ... Drugs.com provides accurate and independent ...
- Xantinol Nicotinate tablets are vasodilating agents.Each tablet of Xantinol Nicotinate 150mg dosage costs $0.93. Order with us and save more. ... What is Xantinol Nicotinate used for? Xantinol Nicotinate is a vasodilator prescribed to ...
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ニコチン酸キサンチノール
- 関
- xantinol nicotinate
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- 英
- xantinol nicotinate、xanthinol niacinate
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ニコチン酸、ニコチン酸塩