呼吸筋、換気筋
- 関
- respiratory muscle
WordNet
- make ones way by force; "He muscled his way into the office"
- animal tissue consisting predominantly of contractile cells (同)muscular_tissue
- one of the contractile organs of the body (同)musculus
- authority or power or force (especially when used in a coercive way); "the senators used their muscle to get the party leader to resign"
- a device (such as a fan) that introduces fresh air or expels foul air
- provided with ventilation or involving pulmonary ventilation
PrepTutorEJDIC
- 〈U〉(動物体の組織としての)『筋肉』,筋(きん);〈C〉(体の各部を動かす)筋肉 / 〈U〉力,(特に)筋力,腕力 / 《俗に》(…に)強引に割り込む《+『in on』(『into, through』)+『名』》
- 換気装置,通風機,換気口
- 筋肉の,筋力のある / 力ずくの
UpToDate Contents
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English Journal
- Current treatment and management of dystrophinopathies.
- Goemans N1, Buyse G.Author information 1Department of Child Neurology, University Hospitals Leuven, Herestraat 49, B-3000, Leuven, Belgium, nathalie.goemans@uzleuven.be.AbstractOPINION STATEMENT: • Duchenne muscular dystrophy (DMD), the most common and severe type of dystrophinopathy, is a progressive disease affecting primordially skeletal and cardiac muscle. A coordinated multidisciplinary approach is required to address its multisystemic manifestations and secondary problems.• Treatment with glucocorticosteroids (GCS) is accepted as standard of care in ambulant DMD. Daily and intermittent administrations are both in common use with different efficacy and different side effect profile.• There are no established guidelines for age/stage at initiation and treatment duration of GCS. Common practice is initiation of GCS before the child is starting to decline (between age 3 and 6 years) and continuation of monitored treatment after loss of ambulation, aiming at delaying cardiac and respiratory manifestations and preventing the development of scoliosis.• Prevention, monitoring, and treatment of the side effects of long-term chronic GCS use, such as excessive weight gain, hypertension, osteoporosis, impairment of glucose metabolism, delayed puberty, and cataract, should be integrated in the standards of care.• Noninvasive ventilatory support associated with cough assisting techniques has significantly improved the longevity in DMD.• Pharmacologic treatment for cardiac manifestations includes the standard treatments of dilated cardiomyopathy and arrhythmia such as the use of angiotensin converting enzyme (ACE) inhibitors, beta-blockers and diuretics. The lack of robust controlled data hampers clear recommendations about preventive treatment with ACE inhibitors.• DMD is associated with low bone mineral content, which is aggravated by the use of corticosteroids. The use of biphosphonates can be considered in the treatment of painful vertebral fractures. The use of biphosphonates as a preventive treatment should be investigated in randomized controlled studies.• DMD has evolved from a pediatric disease to an adult condition. This underscores the need to prepare adult neurologists for the optimal surveillance and management of patients with a severe chronic disease that have outgrown the pediatric care and that may develop new disease manifestations with improved longevity.
- Current treatment options in neurology.Curr Treat Options Neurol.2014 May;16(5):287. doi: 10.1007/s11940-014-0287-4.
- OPINION STATEMENT: • Duchenne muscular dystrophy (DMD), the most common and severe type of dystrophinopathy, is a progressive disease affecting primordially skeletal and cardiac muscle. A coordinated multidisciplinary approach is required to address its multisystemic manifestations and secondary p
- PMID 24619767
- Can maximal inspiratory and expiratory pressures during exercise predict complications in patients submitted to major lung resections? A prospective cohort study.
- Refai M1, Pompili C, Salati M, Xiumè F, Sabbatini A, Brunelli A.Author information 1Division of Thoracic Surgery, Ospedali Riuniti, Ancona, Italy.AbstractOBJECTIVES: The measurement of maximal inspiratory pressure (PImax) and maximal expiratory pressure (PEmax) generated at the mouth is an accepted non-invasive clinical method for evaluating the strength of respiratory muscles. The aim of our study was to verify whether PImax and PEmax measured before and after a symptom-limited stair-climbing test are associated with complications in patients submitted to major lung resections.
- European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.Eur J Cardiothorac Surg.2014 Apr;45(4):665-70. doi: 10.1093/ejcts/ezt440. Epub 2013 Sep 25.
- OBJECTIVES: The measurement of maximal inspiratory pressure (PImax) and maximal expiratory pressure (PEmax) generated at the mouth is an accepted non-invasive clinical method for evaluating the strength of respiratory muscles. The aim of our study was to verify whether PImax and PEmax measured befor
- PMID 24067750
- Oxidative capacities of cardiac and skeletal muscles of heart transplant recipients: mitochondrial effects of cyclosporin-A and its vehicle Cremophor-EL.
- N'guessan BB1, Sanchez H, Zoll J, Ribera F, Dufour S, Lampert E, Kindo M, Geny B, Ventura-Clapier R, Mettauer B.Author information 1Service de Physiologie Clinique et des Explorations Fonctionnelles, équipe d'accueil EA3072 Hôpitaux Universitaires de Strasbourg, 67091, Strasbourg Cedex, France; Laboratoire de Physiologie, Pharmacologie et Phytothérapie, UFR SN, Université d'Abobo-Adjamé, 02 BP 801 Abidjan 02, Abidjan, Côte d'Ivoire; Department of Pharmacology and Toxicology, School of Pharmacy, College of Health Sciences, University of Ghana, PO Box KB 52, Korle Bu, Accra, Ghana.AbstractChronic immunosuppressive treatment was suspected to alter maximal muscle oxidative capacity (Vmax ) of heart transplant recipients, leading to a limitation of their exercise tolerance. It remains undefined whether the mitochondrial respiratory chain (MRC) of right ventricle (RV) and vastus lateralis (VL) muscles were altered by immunosuppressants and/or their vehicles. Vmax was measured polarographically in saponin-skinned fibres of RV and VL biopsies of patients and compared with Vmax of healthy VL and myocardium. Effects of increasing concentrations (1-10-100 μM) of Sandimmune(®) , its vehicle, Cyclosporine (CsA) in ethanol (EtOH), or EtOH alone were tested. The vehicle's effects on MRC complexes were investigated using specific substrates and inhibitors. Ten months after grafting, Vmax of RV and VL of immunosuppressed patients were similar to their Vmax at time of transplantation and to that of control tissues. In Vitro, Sandimmune(®) significantly decreased Vmax while CsA in EtOH or EtOH exerted small and similar effects. Effects of the vehicle were higher than (RV) or identical to (VL) those of Sandimmune(®) . The sites of action of the vehicle on MRC were located on complexes I and IV. While unchanged under chronic immunosuppressive therapy, Vmax of RV and VL muscles was depressed by acute exposure to intravenous Sandimmune(®) in vitro, an effect attributed to its vehicle by inhibition of complexes I and IV of the MRC. This work provides an in vitro proof of a toxic effect on the mitochondria respiratory chain of the vehicle used in the intravenous formulation of Sandimmune(®) but with no clinical consequences in chronically immunosuppressed patients.
- Fundamental & clinical pharmacology.Fundam Clin Pharmacol.2014 Apr;28(2):151-60. doi: 10.1111/fcp.12002. Epub 2012 Oct 9.
- Chronic immunosuppressive treatment was suspected to alter maximal muscle oxidative capacity (Vmax ) of heart transplant recipients, leading to a limitation of their exercise tolerance. It remains undefined whether the mitochondrial respiratory chain (MRC) of right ventricle (RV) and vastus laterali
- PMID 23046032
Japanese Journal
- Central and Peripheral Hemodynamic Adaptations During Cardiopulmonary Exercise Test in Heart Failure Patients With Exercise Periodic Breathing
- Fu Tieh-Cheng,Chou Szu-Ling,Chen Tai-Tzung,Wang Chao-Hung,Chang Hen-Hong,Wang Jong-Shyan
- International Heart Journal 56(4), 432-438, 2015
- … Some heart failure (HF) patients develop ventilatory oscillation which is composed of exercise periodic breathing (EPB) and sleep apnea. … The ventilatory oscillation is associated with exercise intolerance. … A noninvasive bio-reactance device was adopted to measure cardiac hemodynamics, whereas a near-infrared spectroscopy (NIRS) was used to assess perfusion and O2 extraction in the frontal cerebral lobe (FC) and vastus lateralis muscle (VL) during exercise respectively. …
- NAID 130005087573
- Central and Peripheral Hemodynamic Adaptations During Cardiopulmonary Exercise Test in Heart Failure Patients With Exercise Periodic Breathing
- Fu Tieh-Cheng,Chou Szu-Ling,Chen Tai-Tzung,Wang Chao-Hung,Chang Hen-Hong,Wang Jong-Shyan
- International Heart Journal advpub(0), 2015
- … Some heart failure (HF) patients develop ventilatory oscillation which is composed of exercise periodic breathing (EPB) and sleep apnea. … The ventilatory oscillation is associated with exercise intolerance. … A noninvasive bio-reactance device was adopted to measure cardiac hemodynamics, whereas a near-infrared spectroscopy (NIRS) was used to assess perfusion and O2 extraction in the frontal cerebral lobe (FC) and vastus lateralis muscle (VL) during exercise respectively. …
- NAID 130005078540
- 急性呼吸不全における人工呼吸モードの選択─自発呼吸努力をどう考えるべきか?─
- 内山 昭則
- 日本臨床麻酔学会誌 35(1), 089-097, 2015
- 重症患者における人工呼吸法のこれまでの歴史的な進歩の一つは自発呼吸努力と人工呼吸器をうまく同調させることであった.自発呼吸努力との同調性がよい人工呼吸モードの発展は患者の快適性を改善し,人工呼吸器と自発呼吸の不同調による肺合併症の発生を減少させてきた.人工呼吸器の発展によって人工呼吸中の鎮静薬の使用量を減らせたことは集中治療を必要とする患者の予後の改善につながっている.このように重症の急性呼吸 …
- NAID 130004892982
Related Links
- J Appl Physiol. 1996 Oct;81(4):1455-68. Regulation of ventilatory muscle blood flow. Hussain SN. Department of Medicine, Royal Victoria Hospital, McGill University, Montreal, Quebec Canada. SHUSSAIN@RVHMED.LAN.McGill.Ca ...
Related Pictures
★リンクテーブル★
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- 英
- ventilatory muscle
- 関
- 呼吸筋
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呼吸筋
- 関
- ventilatory muscle
[★]
- 関
- tidal、ventilate、ventilation
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