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1. 心不全患者における高血圧治療 treatment of hypertension in patients with heart failure
2. 安定狭心症のマネージメントにおける硝酸塩 nitrates in the management of stable angina pectoris
3. 特発性低髄液圧性頭痛の病態生理、臨床的特徴、および診断 pathophysiology clinical features and diagnosis of spontaneous low cerebrospinal fluid pressure headache
4. 心不全患者における利尿剤の使用 use of diuretics in patients with heart failure
5. 麻酔後ケア病棟における合併症発生の概要 overview of complications occurring in the post anesthesia care unit

English Journal

Elevated guanylate cyclase and cyclic-guanosine monophosphate-dependent protein kinase levels in nasal mucosae of antigen-challenged rats.

Sakai H1, Hara T, Todoroki K, Igarashi Y, Misawa M, Narita M, Chiba Y.
Microvascular research.Microvasc Res.2013 Nov;90:150-3. doi: 10.1016/j.mvr.2013.08.009. Epub 2013 Sep 5.
OBJECTIVE: In patients with severe allergic rhinitis, the most serious symptom is rhinostenosis, which is considered to be induced by a dilatation of plexus cavernosum. The vascular relaxing responses to chemical mediators are mainly mediated by the production of nitric oxide (NO). However, the exac
PMID 24012634

Dettoni JL1, Consolim-Colombo FM, Drager LF, Rubira MC, Souza SB, Irigoyen MC, Mostarda C, Borile S, Krieger EM, Moreno H Jr, Lorenzi-Filho G.
Journal of applied physiology (Bethesda, Md. : 1985).J Appl Physiol (1985).2012 Jul;113(2):232-6. doi: 10.1152/japplphysiol.01604.2011. Epub 2012 Apr 26.
Sleep deprivation is common in Western societies and is associated with increased cardiovascular morbidity and mortality in epidemiological studies. However, the effects of partial sleep deprivation on the cardiovascular system are poorly understood. In the present study, we evaluated 13 healthy mal
PMID 22539169

Valchanov KP1, Arrowsmith JE.
European journal of anaesthesiology.Eur J Anaesthesiol.2012 Mar;29(3):121-8. doi: 10.1097/EJA.0b013e32835016be.
A unifying hypothesis which satisfactorily explains the clinical syndrome of heart failure has proved elusive. A deeper understanding of the underlying pathophysiology has led to the development of more complex models and, as a result, the evolution of new treatment strategies. In patients undergoin
PMID 22273830

Involvements of cysteinyl leukotrienes and nitric oxide in antigen-induced venodilatation of nasal mucosa in sensitized rats in vivo

CHIBA Yoshihiko,OSHITA Michiko,SAKAI Hiroyasu,MISAWA Miwa
日本平滑筋学会機関誌 43(4), 139-144, 2007-08
… To determine an in vivo venodilatation of nasal mucosa, which is thought to be one of the causes of nasal obstruction in allergic rhinitis, venous diameters of nasal septa were directly measured in anesthetized rats. … An application of antigen to nasal mucosa of sensitized rats caused an increase in diameters of mucosal veins, that is, venodilatation : the maximal response (about 20% increase in diameters) was observed at 55 min after antigen challenge. …
NAID 110006404994

Selective vasopressin inhibition in rats with heart failure decreases afterload and results in venodilatation

Acute hemodynamic effects of alpha human atrial natriuretic polypeptide in patients with congestive heart failure.

SERIZAWA Takashi,HIRATA Yasunobu,KOHMOTO Osami,IIZUKA Masahiko,MATSUOKA Hiroaki,SATO Hiroshi,TAKAHASHI Toshiyuki,MOCHIZUKI Takatoshi,ISHII Masao,SUGIMOTO Tsuneaki,KANGAWA Kenji,MATSUO Hisayuki
Ｊａｐａｎｅｓｅ　Ｈｅａｒｔ　Ｊｏｕｒｎａｌ 29(2), 143-149, 1988
… In conclusion, α-hANP induced decreases in left ventricular filling pressure and rightside heart pressure which were attributed to venodilatation rather than natriuretis in patients with congestive heart failure. …
NAID 130000765025