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1. 肝肉芽腫 hepatic granulomas
2. 頚部腫瘤の鑑別診断 differential diagnosis of a neck mass

English Journal

Research progress in live attenuated Brucella vaccine development.

Wang Z, Wu Q1.Author information 1Key Laboratory of Animal Epidemiology and Zoonosis of the Ministry of Agriculture, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China. wuqm@cau.edu.cn.AbstractBrucella spp. are facultative intracellular bacteria that cause brucellosis, which is a globally occurring zoonotic disease that is characterized by abortion in domestic animals and undulant fever, arthritis, endocarditis, and meningitis in humans. There are currently no licensed vaccines against brucellosis for human use, and only a few licensed live Brucella vaccines are available for use in animals. However, the available animal vaccines may cause abortion and are associated with lower protection rates in animals and higher virulence in humans. Much research has been performed recently to develop novel Brucella vaccines for the prevention and control of animal brucellosis. This article discusses the approaches and strategies for novel live attenuated vaccine development.
Current pharmaceutical biotechnology.Curr Pharm Biotechnol.2014 Nov;14(10):887-96.
Brucella spp. are facultative intracellular bacteria that cause brucellosis, which is a globally occurring zoonotic disease that is characterized by abortion in domestic animals and undulant fever, arthritis, endocarditis, and meningitis in humans. There are currently no licensed vaccines against br
PMID 24372253

Skin pathology in Hawaiian goldring surgeonfish, Ctenochaetus strigosus (Bennett).

Work TM1, Aeby GS.Author information 1US Geological Survey, National Wildlife Health Center, Honolulu Field Station, Honolulu, HI, USA; Hawaii Institute of Marine Biology, Kane'ohe, HI, USA.AbstractTwenty-eight goldring surgeonfish, Ctenochaetus strigosus (Bennett), manifesting skin lesions and originating from the north-western and main Hawaiian Islands were examined. Skin lesions were amorphous and ranged from simple dark or light discolouration to multicoloured tan to white sessile masses with an undulant surface. Skin lesions covered 2-66% of the fish surface, and there was no predilection for lesions affecting a particular part of the fish. Males appeared over-represented. Microscopy revealed the skin lesions to be hyperplasia, melanophoromas or iridophoromas. The presence of skin tumours in a relatively unspoiled area of Hawaii is intriguing. Explaining their distribution, cause and impact on survivorship of fish all merit further study because C. strigosus is an economically important fish in the region.
Journal of fish diseases.J Fish Dis.2014 Apr;37(4):357-62. doi: 10.1111/jfd.12112. Epub 2013 Apr 26.
Twenty-eight goldring surgeonfish, Ctenochaetus strigosus (Bennett), manifesting skin lesions and originating from the north-western and main Hawaiian Islands were examined. Skin lesions were amorphous and ranged from simple dark or light discolouration to multicoloured tan to white sessile masses w
PMID 23617760

Characterization of the immunogenicity and pathogenicity of malate dehydrogenase in Brucella abortus.

Han X1, Tong Y, Tian M, Sun X, Wang S, Ding C, Yu S.Author information 1Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences (CAAS), 518 Ziyue Road, Shanghai, 200241, People's Republic of China.AbstractBrucella abortus is a gram-negative, facultative intracellular pathogen that causes brucellosis, a chronic zoonotic disease resulting in abortion in pregnant cattle and undulant fever in humans. Malate dehydrogenase (MDH), a key enzyme in the tricarboxylic acid cycle, plays important metabolic roles in aerobic energy producing pathways and in malate shuttle. In this study, the MDH-encoding gene for malate dehydrogenase mdh of B. abortus S2308 was cloned, sequenced and expressed. Western blot analysis demonstrated that MDH is an immunogenic membrane-associated protein. In addition, recombinant MDH showed sero-reactivity with 30 individual bovine B. abortus-positive sera by enzyme-linked immunosorbent assay, indicates that MDH may be used as a candidate marker for sero-diagnosis of brucellosis. Furthermore, MDH exhibits fibronectin and plasminogen-binding ability in immunoblotting assay. Inhibition assays on HeLa cells demonstrated that rabbit anti-serum against MDH significantly reduced both bacterial adherence and invasion abilities (p < 0.05), suggesting that MDH play a role in B. abortus colonization. Our results indicated that MDH is not only an immunogenic protein, but is also related to bacterial pathogenesis and may act as a new virulent factor, which will benefit for further understanding the MDH's roles in B. abortus metabolism, pathogenesis and immunity.
World journal of microbiology & biotechnology.World J Microbiol Biotechnol.2014 Mar 8. [Epub ahead of print]
Brucella abortus is a gram-negative, facultative intracellular pathogen that causes brucellosis, a chronic zoonotic disease resulting in abortion in pregnant cattle and undulant fever in humans. Malate dehydrogenase (MDH), a key enzyme in the tricarboxylic acid cycle, plays important metabolic roles
PMID 24609497

Japanese Journal

Forced Heat Convection of Wavy Fin Channel

YANG Tsun Lirng,CHIANG Kuei Feng,CHANG Shyy Woei,HUANG Chuan Chin
Journal of Thermal Science and Technology 3(2), 342-354, 2008
… Impacts of Reynolds number (Re) and the undulant surface on heat transfer distributions over the wavy fin surface in the Re range of 500-11000 are examined. … Within the Re range tested, the lack of traversing flow momentum over the undulant fin surface prohibits the overall heat transfer elevations from the flat fin levels. …
NAID 130000099068

傾斜農地における土壌の空間変動に関する研究

柏木淳一
北海道大学大学院農学研究院邦文紀要 29(2), 215-305, 2008
… Topography of the investigated field was undulant hills, average slope is 0.24 mm-1 and 80% of the field was steep slope over 0.20 m m-1. …
NAID 120000951880