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1. フィブロネクチン糸球体症 fibronectin glomerulopathy
2. 皮膚剥脱症候群 peeling skin syndrome
3. 頭蓋底の脊索腫および軟骨肉腫 chordoma and chondrosarcoma of the skull base
4. メルケル細胞（神経内分泌）癌の病因、臨床的特徴、および診断 pathogenesis clinical features and diagnosis of merkel cell neuroendocrine carcinoma
5. 膵外分泌腫瘍の病理 pathology of exocrine pancreatic neoplasms

English Journal

Ultrastructure evaluation of goat spermatozoa after freezing in a skim milk-based extender with Trolox supplementation.

Soares AT1, Silva SV, Batista AM, Almeida FC, Nunes JF, Peixoto CA, Guerra MM.Author information 1Andrology Laboratory (ANDROLAB), Veterinary Medicine Department, UFRPE, Recife, PE, Brazil; State Company for Agricultural Research of Paraiba, EMEPA, João Pessoa, PB, Brazil.AbstractThe aim of this work was to evaluate the in vitro effect of adding Trolox in freezing extender for goat semen. Ejaculates from five bucks were evaluated, and when approved, the samples were pooled, diluted according to experimental groups [Trolox 0 (control), 30, 60 and 120 nmol ml-1 ] and frozen in an automated system. Thawed samples (37 °C/30 s) were evaluated for plasma membrane (PMi) and acrosome integrity (Aci), mitochondrial membrane potential (MMP) and sperm kinematics by CASA system. Spermatozoa ultrastructure was evaluated in fresh and post-thawed semen. No significant difference (P > 0.05) was observed among control and Trolox groups in the analyses of PMi, Aci, MMP and CASA in goat spermatozoa after thawing. Samples of 60 and 120 nmol ml-1 Trolox groups had a higher percentage of cells that had intact plasma membranes in spermatozoa head than in the other groups, although they did not differ (P > 0.05) before being frozen. A higher percentage (P < 0.05) of spermatozoa with intact mitochondria was observed in fresh semen, control and Trolox 60 nmol ml-1 groups than in the other groups. Addition of Trolox to skim milk extender at 60 nmol ml-1 ultrastructurally preserves the plasma membrane and mitochondrial sheath integrity in goat spermatozoa after cryopreservation.
Andrologia.Andrologia.2014 Apr 2. doi: 10.1111/and.12279. [Epub ahead of print]
The aim of this work was to evaluate the in vitro effect of adding Trolox in freezing extender for goat semen. Ejaculates from five bucks were evaluated, and when approved, the samples were pooled, diluted according to experimental groups [Trolox 0 (control), 30, 60 and 120 nmol ml-1 ] and frozen
PMID 24698171

Classic and current opinion in embryonic organ transplantation.

Hammerman MR.Author information Departments of Medicine, and Cell Biology and Physiology, Washington University School of Medicine, St. Louis, Missouri, USA.AbstractPURPOSE OF REVIEW: Here, we review the rationale for the use of organs from embryonic donors, antecedent investigations and recent work from our own laboratory, exploring the utility for transplantation of embryonic kidney and pancreas as an organ replacement therapy.
Current opinion in organ transplantation.Curr Opin Organ Transplant.2014 Apr;19(2):133-9. doi: 10.1097/MOT.0000000000000054.
PURPOSE OF REVIEW: Here, we review the rationale for the use of organs from embryonic donors, antecedent investigations and recent work from our own laboratory, exploring the utility for transplantation of embryonic kidney and pancreas as an organ replacement therapy.RECENT FINDINGS: Ultrastructural
PMID 24535425

Brush cytology of acinar cell carcinoma of the pancreas with intraductal growth: A case report.

Toyonaga Y1, Yamazaki K, Yamada M, Koyasu T, Koyama Y, Ishida Y.Author information 1Department of Pathology, Teikyo University, Chiba Medical Center, Ichihara, Japan.AbstractWe describe a rare case of pancreatic acinar cell carcinoma (ACC) with intraductal growth in a 77-year-old man, which was diagnosed by endoscopic brush cytology. Preoperative imaging revealed an ill-defined mass involving the main pancreatic duct of the body, which was suspected to be an invasive ductal carcinoma. Endoscopic brush cytology showed several thick, small to large clusters of tumor cells. However, a loosely cohesive or individual cell arrangement was more prominent. Singly dispersed naked nuclei, occasionally with crush artifact, were frequently observed. The nuclear contour was smooth and chromatin was finely clumped. The cytoplasm contained many coarse D-PAS-positive granules. Histologically, the tumor expansively invaded to parenchyma and expanded to fill the pancreatic ducts. Ultrastructurally, the tumor cells were less cohesive with scarce tight junctions, and their cytoplasm contained numerous zymogen granules and filamentous inclusions. Although ACCs usually show expansive growth, the incidence of intraductal extension may be higher than previously considered. A few of the characteristic cytomorphological features described here may be useful for differential diagnosis of this tumor from malignant epithelioid neoplasms involving the large pancreatic ducts. Diagn. Cytopathol. 2014;42:321-324. © 2013 Wiley Periodicals, Inc.
Diagnostic cytopathology.Diagn Cytopathol.2014 Apr;42(4):321-4. doi: 10.1002/dc.23087. Epub 2013 Dec 20.
We describe a rare case of pancreatic acinar cell carcinoma (ACC) with intraductal growth in a 77-year-old man, which was diagnosed by endoscopic brush cytology. Preoperative imaging revealed an ill-defined mass involving the main pancreatic duct of the body, which was suspected to be an invasive du
PMID 24376257

Japanese Journal

淡明細胞型肝内胆管癌の 1 例

山口直則,益澤尚子,今村好章,松居由香,岸本光夫
日本臨床細胞学会雑誌 54(2), 146-152, 2015
背景 : 淡明細胞型肝内胆管癌は淡明な細胞からなる肝内胆管癌の特殊型で極めてまれである. 今回, その 1 例を経験したので報告する. 症例 : 63 歳, 女性. 腹痛を主訴に来院し, 造影 CT にて肝右葉に早期相で不均一に濃染する約 6 cm 大の多結節状腫瘤を指摘され, 肝右葉切除術が施行された. 捺印細胞診では偏在した不整形核と腫大した核小体をもつ腫瘍細胞がみられた. 核溝や核内細胞質封 …
NAID 130005071166

Ultrastructural study on the morphological changes in indigenous bacteria of mucous layer and chyme throughout the rat intestine

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Journal of Veterinary Medical Science advpub(0), 2015
… Therefore, the present study aimed to ultrastructurally clarify the degeneration and viability status of indigenous bacteria in the rat intestine. … From these findings, indigenous bacteria in the mucous layer were ultrastructurally confirmed to be the source of indigenous bacteria in the chyme. …
NAID 130005064939

Immunohistochemical and ultrastructural investigation of acinar cells in submandibular and sublingual glands of rats fed a liquid diet

Takahashi S.,Uekita H.,Kato T.,Yuge F.,Ushijima N.,Inoue K.,Domon T.
Tissue & Cell 46(2), 136-143, 2014-04
… Submandibular and sublingual glands were weighed and examined histologically, ultrastructurally, and immunohistochemically using antibodies to cleaved caspase-3 (Casp-3) and 5-bromo-2'-deoxyuridine (BrdU). …
NAID 120005455898