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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2012/07/20 01:12:12」(JST)

Tribenoside is a vasoprotective and a mixture of the α- und β-anomers.

Induction of hypersensitivity has been reported.^[1]

References

^ Hashizume H, Takigawa M (2005). "Drug-induced hypersensitivity syndrome associated with cytomegalovirus reactivation: immunological characterization of pathogenic T cells". Acta Derm. Venereol. 85 (1): 47–50. DOI:10.1080/00015550410024094. PMID 15848991. http://adv.medicaljournals.se/article/full/10.1080/00015550410024094.

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Teratogenic potential of tribenoside, a drug for the treatment of haemorrhoids and varicose veins--a population-based case--control study.

Kubicsek T, Kazy Z, Czeizel AE.SourceSecond Department of Obstetrics and Gynecology, Semmelweis University, School of Medicine, Budapest, Hungary.
Reproductive toxicology (Elmsford, N.Y.).Reprod Toxicol.2011 May;31(4):464-9. Epub 2010 Dec 21.
Tribenoside is used for the treatment of haemorrhoids and varicose veins, frequently in pregnant women as well, but published data regarding its possible teratogenic effect are not available. Thus the risk of congenital abnormalities (CAs) was estimated in cases of pregnant women with oral tribenosi
PMID 21182931

The influence of Tribenoside on expression and deposition of epidermal laminins in HaCaT cells.

Kikkawa Y, Takaki S, Matsuda Y, Okabe K, Taniguchi M, Oomachi K, Samejima T, Katagiri F, Hozumi K, Nomizu M.SourceLaboratory of Clinical Biochemistry, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo 192-0392, Japan. kikkawa@toyaku.ac.jp
Biological & pharmaceutical bulletin.Biol Pharm Bull.2010 Feb;33(2):307-10.
Tribenoside has been used clinically for hemorrhoidal disease associated with coagulation, inflammation, and wounds. However, the pharmacological mechanism of tribenoside activity has never been clear. In this study we examined whether tribenoside affected expression and deposition of laminins that
PMID 20118558

The Influence of Tribenoside on Expression and Deposition of Epidermal Laminins in HaCaT Cells

Kikkawa Yamato,Takaki Shu,Matsuda Yuji,Okabe Koichi,Taniguchi Masakazu,Oomachi Kengo,Samejima Teruyuki,Katagiri Fumihiko,Hozumi Kentaro,Nomizu Motoyoshi
Biological & Pharmaceutical Bulletin 33(2), 307-310, 2010
… Tribenoside has been used clinically for hemorrhoidal disease associated with coagulation, inflammation, and wounds. … However, the pharmacological mechanism of tribenoside activity has never been clear. … In this study we examined whether tribenoside affected expression and deposition of laminins that are required for reconstruction of basement membranes (BMs) during wound healing in hemorrhoidal disease. …
NAID 130000156642

Tribenoside-Lidocane 含有坐剤 (Borraza G^<【encircled R】>坐剤,BG-356) の薬理作用:痔疾モデルにおける抗浮腫作用,創傷治癒促進作用

リンク元

Tribenoside
Systematic (IUPAC) name
	ethyl 3,5,6-tri-O-benzyl-D-glucofuranoside
Clinical data
AHFS/Drugs.com	International Drug Names
Pregnancy cat.	?
Legal status	?
Identifiers
CAS number	10310-32-4
ATC code	C05AX05 C05CX01
PubChem	CID 25145
UNII	Z7N0Y673NU
ChEMBL	CHEMBL1446743
Synonyms	(3R,4R,5R)-4-(benzyloxy)-5-[1,2-bis(benzyloxy)ethyl]-2-ethoxyoxolan-3-ol
Chemical data
Formula	C29H34O6
Mol. mass	478.57666 g/mol
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