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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/07/26 11:10:15」(JST)

Tretoquinol is a beta-adrenergic agonist.^[1]^[2]

References

^ "Synthesis of 6,7-dihydrox-1,2,3,4-tetrahydroisoquinoline derivatives". Tetrahedron 22: 129–134. doi:10.1016/S0040-4020(01)82177-3.
^ "β-Adrenoceptor Subtype Activities of Trimetoquinol Derivatives: Biochemical Studies on Human β-Adrenoceptors Expressed in Chinese Hamster Ovary Cells". Jpet.aspetjournals.org. 1999-11-01. Retrieved 2012-08-20.

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Endogenous neurotoxic dopamine derivative covalently binds to Parkinson's disease-associated ubiquitin C-terminal hydrolase L1 and alters its structure and function.

Contu VR1, Kotake Y, Toyama T, Okuda K, Miyara M, Sakamoto S, Samizo S, Sanoh S, Kumagai Y, Ohta S.
Journal of neurochemistry.J Neurochem.2014 Sep;130(6):826-38. doi: 10.1111/jnc.12762. Epub 2014 Jun 18.
Parkinson's disease (PD) is a common neurodegenerative disease, but its pathogenesis remains elusive. A mutation in ubiquitin C-terminal hydrolase L1 (UCH-L1) is responsible for a form of genetic PD which strongly resembles the idiopathic PD. We previously showed that 1-(3',4'-dihydroxybenzyl)-1,2,3
PMID 24832624

Lateral hypothalamic area deep brain stimulation for refractory obesity: a pilot study with preliminary data on safety, body weight, and energy metabolism.

Whiting DM1, Tomycz ND, Bailes J, de Jonge L, Lecoultre V, Wilent B, Alcindor D, Prostko ER, Cheng BC, Angle C, Cantella D, Whiting BB, Mizes JS, Finnis KW, Ravussin E, Oh MY.
Journal of neurosurgery.J Neurosurg.2013 Jul;119(1):56-63. doi: 10.3171/2013.2.JNS12903. Epub 2013 Apr 5.
OBJECT: Deep brain stimulation (DBS) of the lateral hypothalamic area (LHA) has been suggested as a potential treatment for intractable obesity. The authors present the 2-year safety results as well as early efficacy and metabolic effects in 3 patients undergoing bilateral LHA DBS in the first study
PMID 23560573

Leg swelling after inguinal sentinel lymph node biopsy and primary melanoma excision with a safety margin.

Kretschmer L1, Pratsch AL.
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG.J Dtsch Dermatol Ges.2012 Oct;10(10):733-9. doi: 10.1111/j.1610-0387.2012.07941.x. Epub 2012 Jun 12.
BACKGROUND: Risk-factors for leg swelling following primary melanoma excision and inguinal sentinel lymphadenectomy (SLNE) have not been sufficiently investigated.PATIENTS AND METHODS: We prospectively studied three parameters in 105 subjects: 1) subjectively perceived swelling, 2) clinically diagno
PMID 22686498

リンク元	「trimetoquinol」「トレトキノール」

Tretoquinol
Names
	IUPAC name (1S)-1-[(3,4,5-Trimethoxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol
Identifiers
CAS Number	30418-38-3
ChEMBL	ChEMBL174984
ChemSpider	59192
Jmol 3D model	Interactive image
MeSH	Tretoquinol
PubChem	65772
UNII	JIO3275WGI
	InChI InChI=1S/C19H23NO5/c1-23-17-7-11(8-18(24-2)19(17)25-3)6-14-13-10-16(22)15(21)9-12(13)4-5-20-14/h7-10,14,20-22H,4-6H2,1-3H3/t14-/m0/s1 Key: RGVPOXRFEPSFGH-AWEZNQCLSA-N ; InChI=1/C19H23NO5/c1-23-17-7-11(8-18(24-2)19(17)25-3)6-14-13-10-16(22)15(21)9-12(13)4-5-20-14/h7-10,14,20-22H,4-6H2,1-3H3/t14-/m0/s1 Key: RGVPOXRFEPSFGH-AWEZNQCLBM ;
	SMILES O(c1cc(cc(OC)c1OC)C[C@H]3c2c(cc(O)c(O)c2)CCN3)C ;
Properties
Chemical formula	C19H23NO5
Molar mass	345.39 g/mol
Pharmacology
ATC code	R03AC09 (WHO)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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	Infobox references