WordNet
- a result; "this situation developed in response to events in Africa"
- a phrase recited or sung by the congregation following a versicle by the priest or minister
- the manner in which an electrical or mechanical device responds to an input signal or a range of input signals
- (genetics) the organic process whereby the DNA sequence in a gene is copied into mRNA; the process whereby a base sequence of messenger RNA is synthesized on a template of complementary DNA
- a sound or television recording (e.g., from a broadcast to a tape recording)
- something written, especially copied from one medium to another, as a typewritten version of dictation (同)written text
PrepTutorEJDIC
- 〈C〉(…に対する)『返事』,『返答』《+『to』+『名』》 / 〈C〉〈U〉(…に対する)『反応』,『反響』《『to』+『名』》 / 〈C〉応答歌,応唱(牧師にならって合唱隊・会衆が短い祈り・歌を応答すること)
- 〈U〉(…を)書き写す(書き直す)こと,(…の)転写,謄写《+of+名》 / 〈C〉写し(書き直し)[たもの] / 〈U〉〈C〉編曲[されたもの] / 〈U〉〈C〉(ラジオ・テレビの)録音(録画)
UpToDate Contents
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English Journal
- [The testing strategy for detection of biologically relevant infection of human papillomavirus in head and neck tumors for routine pathological analysis].
- Kašpírková J, Ondič O, Cerná K, Skálová A.AbstractThere is a subgroup among head and neck squamous cell carcinomas, which is etiologically linked to the infection of high-risk human papillomavirus (HPV). In recent studies, HPV related squamous cell carcinomas have been placed in a separate group because of their different epidemiology, distinctive histopathological characteristics, therapeutic response and clinical outcome. The reported prevalence of high-risk HPV in head and neck tumors varies in different studies. This fact occurs mainly due to the absence of a widely accepted consensus for HPV detection in head and neck malignancies. We present a methodological algorithm for detection of biologically relevant HPV infection: a combination of an immunohistochemical staining of the p16 protein - a surrogate marker for a transforming HPV infection, and a molecular genetic identification of HPV DNA by three different polymerase chain reactions (PCR). The study group consisted of 41 patients with a tumor in head and neck region. A verification of detection of biologically relevant HPV infection has been performed in 10 available samples using an alternative approach, which comprised the detection of RNA transcript of HPV by reverse transcription followed by PCR (RT-PCR), and further in situ hybridization (ISH) with a commercial high-risk HPV probe. We have found a high correlation between HPV DNA detection using triple-PCR approach and strong diffuse positivity of the p16 protein (correlation coefficient 0.94) and have confirmed the validity of this algorithm. In 94 % of HPV related squamous cell carcinomas HPV type 16 was detected. In one case HPV type 33 was identified. That is in agreement with earlier published data. A more appropriate alternative method for the detection of biologically relevant- transforming HPV infection seems to be RT-PCR, which proved 100 % agreement with the original methodological approach of p16 determination and PCR status. Interpretation of the ISH has been complicated by frequent nonspecific staining of the sample and its routine usage in the diagnostic algorithm of our laboratory is currently not feasible.Keywords: HPV - squamous cell carcinoma - head and neck tumors - p16.
- Ceskoslovenská patologie.Cesk Patol.2013 Dec;49(1):29-34.
- There is a subgroup among head and neck squamous cell carcinomas, which is etiologically linked to the infection of high-risk human papillomavirus (HPV). In recent studies, HPV related squamous cell carcinomas have been placed in a separate group because of their different epidemiology, distinctive
- PMID 23432073
- Proteomic changes induced by histone demethylase JMJD3 in TNF alpha-treated human monocytic (THP-1) cells.
- Das A, Das ND, Jung KH, Park JH, Lee HT, Han D, Choi MR, Kang SC, Chai YG.SourceDepartment of Molecular & Life Science, Hanyang University, Ansan, 426-791, Republic of Korea. Electronic address: amitabhdas.kn@gmail.com.
- Molecular immunology.Mol Immunol.2013 Nov;56(1-2):113-22. doi: 10.1016/j.molimm.2013.04.013. Epub 2013 May 25.
- JMJD3, a Jumonji C family histone demethylase, plays an important role in the regulation of inflammation induced by the transcription factor nuclear factor-kappa B (NF-κB) in response to various stimuli. JMJD3 is a histone-3 lysine-27 trimethylation (H3K27me3) demethylase, a histone mark associated
- PMID 23711388
- NFATc2 recruits cJun homodimers to an NFAT site to synergistically activate interleukin-2 transcription.
- Walters RD, Drullinger LF, Kugel JF, Goodrich JA.SourceUniversity of Colorado, Department of Chemistry and Biochemistry, 596 UCB, Boulder, CO 80303-0596, United States.
- Molecular immunology.Mol Immunol.2013 Nov;56(1-2):48-56. doi: 10.1016/j.molimm.2013.03.022. Epub 2013 May 9.
- Transcription of interleukin-2 (IL-2), a pivotal cytokine in the mammalian immune response, is induced by NFAT and AP-1 transcriptional activators in stimulated T cells. NFATc2 and cJun drive high levels of synergistic human IL-2 transcription, which requires a unique interaction between the C-termi
- PMID 23665382
Japanese Journal
- Transcriptional response of Lactobacillus acidophilus L-92 after attachment to epithelial Caco-2 cells
- Yanagihara Sae,Hirota Tatsuhiko,Yamamoto Naoyuki
- Journal of bioscience and bioengineering 114(6), 582-585, 2012-12
- NAID 40019531740
- 自然免疫における転写後調節 (第1土曜特集 自然免疫Update : 研究最前線) -- (シグナル)
- Overexpression of GSH1 gene mimics transcriptional response to low temperature during seed vernalization treatment of Arabidopsis
- HATANO IWASAKI Aya,OGAWA Ken'ichi
- Plant and cell physiology 53(7), 1195-1203, 2012-07-01
- NAID 10030963174
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- transcriptional response
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- 転写応答
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- transcriptional response
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- 転写反応
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- transcriptionally