WordNet

any specific behavior; "they avoided all recreational activity"
(chemistry) the capacity of a substance to take part in a chemical reaction; "catalytic activity"

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1. 性行為に伴う一次性頭痛 primary headache associated with sexual activity
2. 臨床試験および臨床における関節リウマチの活動性の評価 assessment of rheumatoid arthritis activity in clinical trials and clinical practice
3. 心血管疾患患者における性的活動 sexual activity in patients with cardiovascular disease
4. 低カリウム血症を合併した高血圧症へのアプローチ approach to the patient with hypertension and hypokalemia
5. 癌生存における食事、身体活動、および体重の役割 the roles of diet physical activity and body weight in cancer survivorship

Targeting polo-like kinase 1, a regulator of p53, in the treatment of adrenocortical carcinoma.

Bussey KJ1,2, Bapat A3, Linnehan C4, Wandoloski M5, Dastrup E6, Rogers E7, Gonzales P8, Demeure MJ9.
Clinical and translational medicine.Clin Transl Med.2016 Dec;5(1):1. doi: 10.1186/s40169-015-0080-3. Epub 2016 Jan 11.
BACKGROUND: Adrenocortical carcinoma (ACC) is an aggressive cancer with a 5 year survival rate of 20-30 %. Various factors have been implicated in the pathogenesis of ACC including dysregulation of the G2/M transition and aberrant activity of p53 and MDM2. Polo-like kinase 1 (PLK-1) negatively mod
PMID 26754547

A galectin related protein from Oplegnathus fasciatus: Genomic, molecular, transcriptional features and biological responses against microbial pathogens.

Thulasitha WS1, Whang I2, Umasuthan N1, Kang HS3, Mothishri MS1, Lee S1, Qiang W1, Noh JK4, Lee J5.
Developmental and comparative immunology.Dev Comp Immunol.2016 Mar;56:13-24. doi: 10.1016/j.dci.2015.11.011. Epub 2015 Nov 22.
Galectins, a family of β-galactoside-binding lectins, are pattern recognition receptors that recognize pathogen-associated molecular patterns and are subsequently involved in the opsonization, phagocytosis, complement activation, and killing of microbes. Here, we report a novel galectin related pro
PMID 26615008

Toll-like receptor-3 mediates HIV-1 transactivation via NFκB and JNK pathways and histone acetylation, but prolonged activation suppresses Tat and HIV-1 replication.

Bhargavan B1, Woollard SM2, Kanmogne GD3.
Cellular signalling.Cell Signal.2016 Feb;28(2):7-22. doi: 10.1016/j.cellsig.2015.11.005. Epub 2015 Nov 11.
TLR3 has been implicated in the pathogenesis of several viral infections, including SIV- and HIV-1-induced inflammation and AIDS. However the molecular mechanisms of these TLR3-mediated effects are not known, and it is not known whether HIV interacts with cellular TLR3 to affect disease process. Her
PMID 26569339

Sphingosine-1-phosphate as a mediator involved in development of fibrotic diseases

Takuwa Yoh,Ikeda Hitoshi,Okamoto Yasuo,Takuwa Noriko,Yoshioka Kazuaki
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids 1831(1), 185-192, 2013-01-00
… The cross-talks include the regulation of S1P production through altered expression and activity of sphingosine kinases in fibrotic lesions, altered expression of S1P receptors, and S1P receptor-mediated transactivation of TGFβ signaling pathway. …
NAID 120004966619

SlICE1 encoding a MYC-type transcription factor controls cold tolerance in tomato, Solanum lycopersicum

Miura Kenji,Shiba Hayato,Ohta Masaru [他],KANG Seung Won,SATO Ayaka,YUASA Takashi,IWAYA INOUE Mari,KAMADA Hiroshi,EZURA Hiroshi
Plant biotechnology 29(3), 253-260, 2012-06-25
Many abiotic and biotic stresses can reduce plant growth and development. Low temperature is one of the most harmful abiotic stresses, particularly for plants that are tropical or subtropical in origi …
NAID 10030804650

Yangonin Blocks Tumor Necrosis Factor-α-Induced Nuclear Factor-κB-Dependent Transcription by Inhibiting the Transactivation Potential of the RelA/p65 Subunit

Ma Juan,Liang He,Jin Hong Ri [他],DAT Nguyen Tien,ZHANG Shan Yu,JIANG Ying Zi,NAN Ji Xing,LI Donghao,WU Xue,LEE Jung Joon,JIN Xuejun
Journal of pharmacological sciences 118(4), 447-454, 2012-04-20
… In the present study, we demonstrate that yangonin potently inhibits NF-κB activation through suppression of the transcriptional activity of the RelA/p65 subunit of NF-κB. … (IκBα) degradation, p65 nuclear translocation, and DNA-binding activity of NF-κB. …
NAID 10030571954