WordNet

of or relating to or caused by a toxin or poison; "suffering from exposure to toxic substances"

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1. 急性腎障害（急性腎不全）または慢性腎臓病患者に対する診断的アプローチ diagnostic approach to the patient with acute kidney injury acute renal failure or chronic kidney disease
2. 成人における慢性腎臓病マネージメントの概要 overview of the management of chronic kidney disease in adults
3. 小児における慢性腎臓病のマネージメントの概要 overview of the management of chronic kidney disease in children
4. 急性および慢性腎臓病における高血圧の概要 overview of hypertension in acute and chronic kidney disease
5. 悪性腫瘍関連腎疾患の概要 overview of renal disease associated with malignancy

The Protective Effect of Apocynin on Cyclosporine A-Induced Hypertension and Nephrotoxicity in Rats.

Ciarcia R1, Damiano S1, Florio A1, Spagnuolo M2, Zacchia E2, Squillacioti C1, Mirabella N1, Florio S1, Pagnini U1, Garofano T3, Polito MS4, Capasso G2, Giordano A4,5.
Journal of cellular biochemistry.J Cell Biochem.2015 Sep;116(9):1848-56. doi: 10.1002/jcb.25140.
Cyclosporine A (CsA) is the prototype of immunosuppressant drugs that has provided new perspectives in human and veterinary medicine to prevent organ transplant rejection and to treat certain autoimmune diseases and dermatologic diseases. Unfortunately, the treatment with CSA is often limited by sev
PMID 25704923

Brune K1, Renner B1, Tiegs G2.
European journal of pain (London, England).Eur J Pain.2015 Aug;19(7):953-65. doi: 10.1002/ejp.621. Epub 2014 Nov 27.
Acetaminophen/paracetamol is the most widely used drug of the world. At the same time, it is probably one of the most dangerous compounds in medical use, causing hundreds of deaths in all industrialized countries due to acute liver failure (ALF). Publications of the last 130 years found in the usual
PMID 25429980

Lipid nanoparticle delivery of a microRNA-145 inhibitor improves experimental pulmonary hypertension.

McLendon JM1, Joshi SR2, Sparks J3, Matar M3, Fewell JG3, Abe K4, Oka M5, McMurtry IF6, Gerthoffer WT2.
Journal of controlled release : official journal of the Controlled Release Society.J Control Release.2015 Jul 28;210:67-75. doi: 10.1016/j.jconrel.2015.05.261. Epub 2015 May 13.
Therapies that exploit RNA interference (RNAi) hold great potential for improving disease outcomes. However, there are several challenges that limit the application of RNAi therapeutics. One of the most important challenges is effective delivery of oligonucleotides to target cells and reduced delive
PMID 25979327

Mechanism of the Cardioprotective Effects of Docetaxel Pre-administration Against Adriamycin-Induced Cardiotoxicity

Tomonari Mari,To Hideto,Nishida Motohiro [他],MISHIMA Takashi,SASAKI Hitoshi,KUROSE Hitoshi
Journal of pharmacological sciences 115(3), 336-345, 2011-03-20
… We revealed that pre-treatment with docetaxel (DOC) 12 h before adriamycin (ADR) administration significantly reduced ADR-induced toxic death compared with the simultaneous dosing schedule that was commonly used in previous studies. … When ADR and/or DOC was intravenously administered, the DOC pre-treatment (DOC-ADR) group showed significantly less toxic death than the ADR-alone group. …
NAID 10029892637

Yamabe Noriko,Kang Ki Sung,Park Chan Hum [他],Zhao Qi,Matsumoto Kinzo,Shibahara Naotoshi,Yokozawa Takako
Journal of Traditional Medicines 28(1), 1-9, 2011
… Traditional Chinese medicine (TCM) has received much attention as a source of novel therapeutic agents due to their multiple beneficial effects and absence of toxic and/or side effects. … Also, Kangen-karyu exerts its renoprotective potential mainly through its antioxidant properties during the development of diabetic nephropathy in type 2 diabetes. …
NAID 130004942372

Uchida Hideomi,Kurata Yoshimasa,Hiratsuka Hideaki,Umemura Takashi
Toxicologic Pathology 38(5), 730-737, 2010-08
… Osteoporosis with osteomalacia, tubular nephropathy, fibrous osteodystrophy and bone marrow hyperplasia occurred following Cd treatment. … In rats treated with Cd and administered a vitamin D deficient diet, the toxic effects of Cd on kidney, bone and hematopoiesis were enhanced in comparison to rats treated with the Cd and a normal diet. …
NAID 120003207592