- 関
- tinoridine
WordNet
- a complex consisting of an organic base in association with hydrogen chloride
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English Journal
- Effects of mepirizole and basic antiinflammatory drugs on HCl-ethanol-induced gastric lesions in rats.
- Tanaka H, Nakagawa M, Takeuchi K, Okabe S.SourceDepartment of Applied Pharmacology, Kyoto Pharmaceutical University, Japan.
- Digestive diseases and sciences.Dig Dis Sci.1989 Feb;34(2):238-45.
- Mepirozole, a basic antiinflammatory drug and duodenal ulcerogen in laboratory animals, macroscopically protected the gastric mucosa of rats from HCl-ethanol-induced damage in a dose-dependent manner. These effects were evident when the agent was given orally, intraperitoneally, or subcutaneously at
- PMID 2914545
- Hydroxyl radical scavenging action of tinoridine.
- Shimada O, Yasuda H.AbstractRadical scavenging action of tinoridine, a non-steroidal anti-inflammatory drug with a potent anti-peroxidative activity, was investigated. Tinoridine reduced a stable free radical, diphenyl-p-picryl-hydrazyl, in the molar ratio of about 1:2, indicating its free radical scavenging ability. Tinoridine inhibited the lipid peroxidation in rat liver microsomes induced by xanthine-xanthine oxidase system in the presence of ADP and Fe2+, in which hydroxyl radical (. OH) is formed. Tinoridine was demonstrated to be oxidized in the course of the lipid peroxidation by following the fluorescence derived from the oxidation product of tinoridine. It was also oxidized by the xanthine-xanthine oxidase system in the presence of Fe2+, but its oxidation was slow in the absence of Fe2+ and almost completely inhibited by catalase. Tinoridine was also oxidized by H2O2-Fe2+ system producing . OH (Fenton reaction), but it did not affect the reduction of cytochrome c caused by superoxide radical. These results indicate that tinoridine is able to scavenge . OH and the main active oxygen species responsible for the lipid peroxidation is . OH. The anti-peroxidative and . OH scavenging ability of tinoridine should contribute to its anti-inflammatory action.
- Agents and actions.Agents Actions.1986 Nov;19(3-4):208-14.
- Radical scavenging action of tinoridine, a non-steroidal anti-inflammatory drug with a potent anti-peroxidative activity, was investigated. Tinoridine reduced a stable free radical, diphenyl-p-picryl-hydrazyl, in the molar ratio of about 1:2, indicating its free radical scavenging ability. Tinoridin
- PMID 3030074
Japanese Journal
- 二重盲検法による Tinoridine hydrochlorideの婦人骨盤内炎症に対する薬効検定
Related Links
- tinoridine hydrochlorideの意味や和訳。 塩酸チノリジン - 約504万語ある英和辞典・ 和英辞典。発音・イディオムも分かる英語辞書。
Related Pictures
★リンクテーブル★
[★]
- 英
- tinoridine、tinoridine hydrochloride
- 関
- 塩酸チノリジン
[★]
- 英
- tinoridine hydrochloride
- 関
- チノリジン
[★]
チノリジン
- 関
- tinoridine hydrochloride
[★]
塩酸塩、ハイドロクロライド