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1. 限局進行性の切除不能（手術不能）食道癌のマネージメントmanagement of locally advanced unresectable and inoperable esophageal cancer [show details]
…trachea. As such, treatment is more closely related to SCC of the head and neck than to thoracic esophageal cancer . As with SCCs of the oropharynx, hypopharynx, and larynx, RT combined with chemotherapy …
2. 限局性食道癌に対する放射線療法、化学放射線療法、術前補助化学療法アプローチ、および補助化学療法radiation therapy chemoradiotherapy neoadjuvant approaches and postoperative adjuvant therapy for localized cancers of the esophagus [show details]
…rather than surgery alone, for patients with T3N0, T4aN0, and clinically node-positive thoracic esophageal cancer, regardless of histology For most patients, we suggest concurrent chemoradiotherapy instead …
3. 切除可能食道癌および食道胃接合部癌に対する外科的マネージメントsurgical management of resectable esophageal and esophagogastric junction cancers [show details]
…commonly practiced in Asian countries for upper thoracic esophageal cancers . In a retrospective review of 1361 patients with squamous cell carcinoma of the thoracic esophagus, the frequency of nodal metastasis …
4. 食道癌の臨床症状、診断、病期分類clinical manifestations diagnosis and staging of esophageal cancer [show details]
… upon accurate preoperative assessment of disease stage. Patients with advanced thoracic or cervical esophageal carcinoma usually present with progressive dysphagia and weight loss. Chronic gastrointestinal …
5. 限局進行性で切除不能の転移性食道癌および胃癌に対する全身療法systemic therapy for locally advanced unresectable and metastatic esophageal and gastric cancer [show details]
…there has also been a shift in the location of esophageal cancers over time. At present, 86 percent of esophageal cancers arise in the distal third of the thoracic esophagus, 13 percent arise in the middle …

English Journal

Inhibition of MUC1-C regulates metabolism by AKT pathway in esophageal squamous cell carcinoma.

GongSun X, Zhao Y, Jiang B, Xin Z, Shi M, Song L, Qin Q, Wang Q, Liu X.
Journal of cellular physiology. 2019 Jul;234(7)12019-12028.
Esophageal squamous cell carcinoma (ESCC) is one of the most common digestive tumors worldwide. The Mucin 1 (MUC1) heterodimeric protein has been confirmed that is overexpressed in ESCC and induced adverse outcomes. However, the detailed mechanism(s) remained challenging. So, we investigated the rel
PMID 30523643

Dosimetric comparison of TomoDirect, helical tomotherapy, VMAT, and ff-IMRT for upper thoracic esophageal carcinoma.

Zhang Y, Wang H, Huang X, Zhang Q, Ren R, Sun R, Zheng Z, Dong S, Zheng A.
Medical dosimetry : official journal of the American Association of Medical Dosimetrists. ;44(2)167-172.
The new TomoDirect (TD) modality offers a nonrotational option with discrete beam angles. We aim to compare dosimetric parameters of TD, helical tomotherapy (HT), volumetric-modulated arc therapy (VMAT), and fixed-field intensity-modulated radiotherapy (ff-IMRT) for upper thoracic esophageal carcino
PMID 29950277

Long non-coding RNA TTN-AS1 promotes the progression of lung adenocarcinoma by regulating PTEN/PI3K/AKT signaling pathway.

Luo J, Liu Z.
Biochemical and biophysical research communications. 2019 Jun;514(1)140-147.
Long non-coding RNA (lncRNAs), which are increasingly identified to be dysregulated in cancers, has been verified to participate in tumorigenesis and cancer development. LncRNA TTN-AS1 has been validated as an oncogene in several cancers, such as esophageal squamous cell carcinoma and cervical cance
PMID 31027732

Japanese Journal

Survival benefit of multimodal local therapy for repeat recurrence of thoracic esophageal squamous cell carcinoma after esophagectomy

Ninomiya Itasu,Okamoto Koichi,Fushida Sachio,Kinoshita Jun,Takamura Hiroyuki,Tajima Hidehiro,Makino Isamu,Miyashita Tomoharu,Ohta Tetsuo
Esophagus : official journal of the Japan Esophageal
NAID 40021807948

壁深達度LPMの食道癌に対する内視鏡切除後に多発転移再発を認めた１例

朝日向良朗,池田博子,林智之,岡藤啓史,寺島健志,鷹取元,北村和哉,山下竜也,水腰英四郎,金子周一
日本消化器内視鏡学会雑誌 61(3), 259-265, 2019
… <p>症例は50歳代，男性．スクリーニング目的で施行された上部消化管内視鏡検査（EGD）で，胸部上部食道に20mm大０-Ⅱc型早期食道癌を指摘されESD施行．病理組織学的にはSCC（squamous cell carcinoma）で，壁深達度pT1a-LPM（lamina propria mucosae），脈管侵襲および垂直断端は陰性であったが，水平断端は判定困難とされ，厳重に経過観察の方針となった．しかし，その後通院自己中断され，ESDを施行した３年８カ月後に頸部リ …
NAID 130007616855

根治的化学放射線治療中に気管食道瘻を合併した進行肺癌に対しSalvage手術を施行した一例

渡辺勇,服部有俊,平山俊希,高持一矢,王志明,鈴木健司
日本呼吸器外科学会雑誌 33(2), 187-193, 2019
<p>48歳男性．咳嗽・胸痛・嚥下困難を認め，胸部CTで右S<sup>2</sup>の4 cmの腫瘤は右下部気管傍リンパ節（#4R）及び気管分岐下リンパ節（#7）と一塊となり，食道浸潤が疑われた．右肺扁平上皮癌（c-T4N2M0 stage IIIB）に対し，根治的化学放射線療法（66 Gy）が開始されるも，26 Gy照射中に発熱し気管食道瘻を認めた．当科へ紹介 …
NAID 130007611901