thermostable

• 耐熱性の、熱安定性の

関

heat resistance、heat tolerance、heat-resistant、heat-stable、thermal stability、thermostability

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/05/05 12:56:28」(JST)

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Thermostability is the quality of a substance to resist irreversible change in its chemical or physical structure at a high relative temperature.

Thermostable materials may be used industrially as fire retardants. A thermostable plastic, an uncommon and unconventional term, is likely to refer to a thermosetting plastic that cannot be reshaped when heated, than to a thermoplastic that can be remelted and recast. Thermostability also commonly refers to a protein resistant to irreversible change in its protein structure due to applied heat.

Thermostable proteins

Most life-forms on Earth live at temperatures of less than 50 °C, commonly from 15 to 50 °C. Above this, thermal energy may cause the unfolding of the protein structure to be irreversible, a condition understandably deleterious to continuing life-functions. The denaturing of proteins in albumen from a clear, nearly colourless liquid to an opaque white, insoluble gel is a common example of this.

Certain thermophilic life-forms exist which can withstand temperatures above this. Examining homologous proteins present in these thermophiles and other organisms reveal only slight differences in the protein structure. One notable difference is the presence of extra hydrogen bonds in the thermophile's proteins—meaning that the protein structure is more resistant to unfolding. The presence of certain types of salt has been observed to decrease thermostability in the proteins of mesophiles but not of hyperthermophiles which may indicate that salt bridges have more impact on thermostability at high temperature than is currently widely acknowledged. Another factors of protein thermostability are compactness of protein structure, oligomerization, and strength interaction between subunits.

Thermostable enzymes such as Taq polymerase and Pfu DNA polymerase are used in polymerase chain reactions where temperatures of 94 °C or over are used to melt apart DNA strands.

Thermostable toxins

Certain poisonous fungi contain thermostable toxins, such as amatoxin found in the death cap and autumn skullcap mushrooms. Therefore, applying heat to these deadly mushrooms will not remove its toxicity.

See also

Thermoregulation in animals
Ectotherm • Endotherm • Poikilotherm • Homeothermy • Heterothermy • Stenotherm • Eurytherm • Thermolabile • Thermostability • Gigantothermy • Kleptothermy • Bradymetabolism • Tachymetabolism

Thermophiles

• Thermus thermophilus
• Thermus aquaticus
• Pyrococcus furiosus

External links

• A Comparison of the Thermostability of Glyceraldehyde 3-phosphate Dehydrogenase From Thermophiles and Mesophiles in Different Ionic Salt Solutions
• Preferred amino acids and thermostability
• Thermostability of Proteins
• Salt Bridges

UpToDate Contents

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English Journal

• Quality-related enzymes in plant-based products: effects of novel food-processing technologies part 3: ultrasonic processing.

• Terefe NS1, Buckow R, Versteeg C.
• Critical reviews in food science and nutrition.Crit Rev Food Sci Nutr.2015;55(2):147-58. doi: 10.1080/10408398.2011.586134.
• High-power ultrasound is a versatile technology which can potentially be used in many food processing applications including food preservation. This is part 2 of a series of review articles dealing with the effectiveness of nonthermal food processing technologies in food preservation focusing on the
• PMID 24915308

• Purification and characterisation of plantaricin ZJ008, a novel bacteriocin against Staphylococcus spp. from Lactobacillus plantarum ZJ008.

• Zhu X1, Zhao Y1, Sun Y1, Gu Q2.
• Food chemistry.Food Chem.2014 Dec 15;165:216-23. doi: 10.1016/j.foodchem.2014.05.034. Epub 2014 May 20.
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• PMID 25038669

• Engineered synergistic thermostable fungal cellulases.

• [No authors listed]
• Biotechnology and bioengineering.Biotechnol Bioeng.2014 Dec;111(12):vi. doi: 10.1002/bit.25462.
• PMID 25349075

Japanese Journal

• Characterization and application of an acidophilic and thermostable β-glucosidase from Thermofilum pendens(ENZYMOLOGY, PROTEIN ENGINEERING, AND ENZYME TECHNOLOGY)

• Li Dan,Li Xiaolei,Dang Wei,Tran Phuong Lan,Park Sung-Hoon,Oh Byung-Chul,Hong Wan-Soo,Lee Jin-Sil,Park Kwan-Hwa
• Journal of bioscience and bioengineering 115(5), 490-496, 2013-05-00
• The gene encoding a β-glucosidase from the archaeon Thermoflium pendens (Tpbgl) was cloned and expressed in Escherichia coli. The purified recombinant enzyme had a molecular mass of 77.8 kDa and relea …
• NAID 110009611451

• Cloning, expression and biochemical characterization of a novel, moderately thermostable GDSL family esterase from Geobacillus thermodenitrificans T2(GENETICS, MOLECULAR BIOLOGY, AND GENE ENGINEERING)

• Yang Zhenxing,Zhang Yong,Shen Tiantian,Xie Yi,Mao Yumin,Ji Chaoneng
• Journal of bioscience and bioengineering 115(2), 133-137, 2013-02-00
• … A thermostable GDSL family esterase-encoding gene, EstL5, was directly obtained from the genomic DNA of Geobacillus thermodenitrificans T2. … Unlike most other thermostable enzymes, EstL5 displayed 24% of its highest activity at 0℃. …
• NAID 110009592560

• Purification and Biochemical Characterization of a Highly Thermostable Bacteriocin Isolated from Brevibacillus brevis Strain GM100

• GHADBANE Mouloud,HARZALLAH Daoud,LARIBI Atef Ibn [他]
• Bioscience, Biotechnology, and Biochemistry 77(1), 151-160, 2013-01-00
• NAID 40019561937

Related Links

• Thermostable β-Agarase - 株式会社ニッポンジーン

Thermostable β -Agaraseは、(独)海洋研究開発機構が深海底泥から発見した耐熱性微生物由来のアガラーゼであり、極めて耐熱性に優れている特長を持っています。 アガラーゼは、アガロースゲルをneoagaro-oligosaccharideに分解する酵素 ...

• Thermostable β-Agarase データ - 株式会社ニッポンジーン

実験例1：アガロースゲルブロックから回収した DNA 断片の PCR 実験例2：アガロースゲルブロックから回収したDNA断片（500bp）のクローニング 実験例3：アガロースゲルブロックから回収したDNA断片（100bp以下）のクローニング

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★リンクテーブル★

リンク元	「thermostability」「耐熱性」「heat tolerance」「heat resistance」「heat-resistant」

「thermostability」

　　[★]

• 熱安定性、耐熱性

関

heat resistance、heat tolerance、heat-resistant、heat-stable、thermal stability、thermostable

「耐熱性」

　　[★]

英

thermostability、heat tolerance、heat resistance、thermostable、heat-resistant

関

熱安定性、耐暑性

「heat tolerance」

　　[★]

• 耐熱性、(植物)耐暑性

関

heat resistance、heat-resistant、thermostability、thermostable

「heat resistance」

　　[★]

• 耐熱性、(植物)耐暑性

関

heat tolerance、heat-resistant、thermostability、thermostable

「heat-resistant」

　　[★]

• 耐熱性の

関

heat resistance、heat tolerance、thermostability、thermostable