- 関
- envelope、peritenon
WordNet
- of or relating to a library or bibliotheca or a librarian (同)bibliothecarial
- a case or sheath especially a pollen sac or moss capsule (同)sac
- outer sheath of the pupa of certain insects
UpToDate Contents
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English Journal
- Short oestrous cycles in sheep during anoestrus involve defects in progesterone biosynthesis and luteal neovascularisation.
- Brown HM, Fabre Nys C, Cognié J, Scaramuzzi RJ.Author information UMR Physiologie de la Reproduction et des Comportements, UMR 6175, INRA-CNRS-Université de Tours-Haras Nationaux, 37380 Nouzilly, France.AbstractAnoestrous ewes can be induced to ovulate by the socio-sexual, 'ram effect'. However, in some ewes, the induced ovulation is followed by an abnormally short luteal phase causing a so-called 'short cycle'. The defect responsible for this luteal dysfunction has not been identified. In this study, we investigated ovarian and uterine factors implicated in male-induced short cycles in anoestrous ewes using a combined endocrine and molecular strategy. Before ovulation, we were able to detect a moderate loss of thecal expression of steroid acute regulatory protein (STAR) in ewes that had not received progesterone priming (which prevents short cycles). At and following ovulation, we were able to identify a significant loss of expression of genes coding key proteins involved in the biosynthesis of progesterone (STAR, CYP11A1 and HSD3B1 (HSD3B)) as well as genes coding proteins critical for vascular development during early luteal development (VEGFA and KDR (VEGFR2)), suggesting dysfunction in at least two pathways critical for normal luteal function. Furthermore, these changes were associated with a significant reduction of progesterone production and luteal weight. Additionally, we cast doubt on the proposed uterus-mediated effect of prostaglandin F2α (PGF2α) as a cause of short cycles by demonstrating the dysregulation of luteal expression of the PGF receptor, which mediates the luteal effects of PGF2α, and by finding no significant changes in the circulating concentrations of PGFM, the principal metabolite of PGF2α in ewes with short cycles. This study is the first of its kind to examine concurrently the endocrine and molecular events in the follicular and early luteal stages of the short cycle. Free French abstract A French translation of this abstract is freely available at http://www.reproduction-online.org/content/147/3/357/suppl/DC1.
- Reproduction (Cambridge, England).Reproduction.2014 Feb 3;147(3):357-67. doi: 10.1530/REP-13-0400. Print 2014.
- Anoestrous ewes can be induced to ovulate by the socio-sexual, 'ram effect'. However, in some ewes, the induced ovulation is followed by an abnormally short luteal phase causing a so-called 'short cycle'. The defect responsible for this luteal dysfunction has not been identified. In this study, we i
- PMID 24357663
- Improved magnetic resonance myelography of the lumbar spine using image fusion and volumetry.
- Eberhardt K, Ganslandt O, Stadlbauer A.Author information MRI Center of Excellence, District Hospital Castle of Werneck, Germany;AbstractObject The goal of this study was to investigate the usefulness and diagnostic potential of an improved MR myelography approach using a dedicated, heavily T2-weighted, 3D MRI sequence in combination with image fusion. A further aim was to compare dural areas and volumes of normal and pathological altered lumbar spine levels, and accuracy in the assessment of the stenoses, with those obtained by postmyelographic CT. Methods Fifty patients underwent myelography, postmyelographic CT, and the improved MR myelography approach using a dedicated, heavily T2-weighted, 3D MRI sequence and image fusion. Dural cross-sectional areas and volumes for normal lumbar levels and levels with stenosis were calculated for postmyelographic CT and MR myelography data. The significant differences and Pearson correlations between dural cross-sectional areas and volumes from L1-2 to L5-S1 of postmyelographic CT and MR myelography were analyzed. The 99% CIs for normal and stenotic levels in patients with claudication distances less than 100 meters were calculated. Results For both dural areas and volumes in normal lumbar levels, the authors found no significant differences and strong correlations between postmyelographic CT and MR myelography. For the lower lumbar levels (L4-5 and L5-S1) they found significantly larger dural areas on MR myelography compared with postmyelographic CT, but not for the upper levels (L2-3 and L3-4). Dural volume analysis revealed significantly larger volumes for MR myelography at all 4 lumbar levels with stenoses in the cohort (L2-3 to L5-S1). Complete separation with no overlap was found between the 99% CIs for normal levels and stenotic levels. Conclusions Differences in dural areas and volumes in this study may have been caused by the fact that in the case of a severely compressed thecal sac, the viscosity of the intrathecally applied contrast agent is too high in the framework of myelography. The gravitationally dependent component is thus too low to achieve sufficient fluid contrast. An optimized MR myelography approach-a dedicated 3D MR myelography sequence with high spatial resolution in combination with image fusion-is required to achieve a more reliable diagnosis of lumbar spine stenoses, especially with severe compression, compared with postmyelographic CT. This MR myelography approach may be helpful in preventing overestimation of lumbar spine stenoses. The upper limits of 99% CIs for stenotic levels can be interpreted as an indication for surgical treatment. However, further studies that include postoperative outcomes are required.
- Journal of neurosurgery. Spine.J Neurosurg Spine.2014 Feb;20(2):220-6. doi: 10.3171/2013.10.SPINE13119. Epub 2013 Dec 13.
- Object The goal of this study was to investigate the usefulness and diagnostic potential of an improved MR myelography approach using a dedicated, heavily T2-weighted, 3D MRI sequence in combination with image fusion. A further aim was to compare dural areas and volumes of normal and pathological al
- PMID 24328762
- Spatial and temporal expression levels of specific microRNAs in a spinal cord injury mouse model and their relationship to the duration of compression.
- Ziu M1, Fletcher L2, Savage JG2, Jimenez DF2, Digicaylioglu M2, Bartanusz V2.Author information 1Department of Neurosurgery, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive (MC 7843), San Antonio, TX 78229, USA. Electronic address: mziu@seton.org.2Department of Neurosurgery, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive (MC 7843), San Antonio, TX 78229, USA.AbstractBACKGROUND CONTEXT: MicroRNAs, a class of small nonprotein-coding RNAs, are thought to control gene translation into proteins. The latter are the ultimate effectors of the biochemical cascade occurring in any physiological and pathological process. MicroRNAs have been shown to change their expression levels during injury of spinal cord in contusion rodent models. Compression is the most frequent mode of damage of neural elements in spinal cord injury. The cellular and molecular changes occurring in the spinal cord during prolonged compression are not very well elucidated. Understanding the underlying molecular events that occur during sustained compression is paramount in building new therapeutic strategies.
- The spine journal : official journal of the North American Spine Society.Spine J.2014 Feb 1;14(2):353-60. doi: 10.1016/j.spinee.2013.08.015. Epub 2013 Oct 23.
- BACKGROUND CONTEXT: MicroRNAs, a class of small nonprotein-coding RNAs, are thought to control gene translation into proteins. The latter are the ultimate effectors of the biochemical cascade occurring in any physiological and pathological process. MicroRNAs have been shown to change their expressio
- PMID 24269082
Japanese Journal
- Synovial Cysts of the Lumbar Spine : Pathological Considerations and Surgical Strategy
- , , , , , ,
- Neurologia medico-chirurgica = 神経外科 53(2), 95-102, 2013-02-15
- … Symptomatic lumbar synovial cysts (LSCs) are a rare cause of degenerative narrowing of the spinal canal, with thecal sac or nerve root compression. …
- NAID 10031138782
- 変形性股関節症を伴う頚椎病変による下肢痙縮に対しバクロフェン髄腔内療法を行い歩行能力の向上が得られた1例
- 山崎 哲朗,池田 巧,上島 圭一郎,三上 靖夫,長谷 斉,久保 秀一,久保 俊一
- 中部日本整形外科災害外科学会雑誌 55(3), 461-464, 2012-05-01
- NAID 10030775470
- Intradural Invasion of Lumbar Synovial Cyst : Case Report
- , , , ,
- Neurologia medico-chirurgica = 神経外科 52(4), 234-237, 2012-04-15
- … Radiological examinations, including magnetic resonance imaging and computed tomography revealed an intradural extramedullary lesion at the L2-3 level that was compressing the thecal sac. …
- NAID 10030127925
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- the·cal (thē'kăl), Relating to a sheath, especially a tendon sheath. [see theca] the·cal (thē′kəl) adj. Of or relating to a sheath, especially a tendon sheath. thecal [thē′kəl] Etymology: Gk, theke, sheath pertaining to a theca or sheath.
Related Pictures
★リンクテーブル★
[★]
- 英
- envelope、thecal
- 関
- エンベロープ、外被、腱鞘、包絡線、封筒
[★]
- 関
- thecal
[★]
- thecal
- 関
- intrathecally、epidural 硬膜外の
[★]
- 関
- intrathecal
[★]
髄腔内注入法 IT injection