タウロデオキシコール酸
- 関
- taurodeoxycholate
WordNet
- street name for lysergic acid diethylamide (同)back breaker, battery-acid, dose, dot, Elvis, loony toons, Lucy in the sky with diamonds, pane, superman, window pane, Zen
- any of various water-soluble compounds having a sour taste and capable of turning litmus red and reacting with a base to form a salt
- having the characteristics of an acid; "an acid reaction"
PrepTutorEJDIC
- 酸性の / 酸味のある,すっぱい(sour) / (言葉・態度などが)厳しい,しんらつな / 酸 / すっぱいもの / 《俗》=LSD
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/05/15 10:31:59」(JST)
[Wiki en表示]
Taurodeoxycholic acid
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Names |
IUPAC name
2-[[(4R)-4-[(3R,5R,8R,9S,10S,12S,13R,14S,17R)-3,12-dihydroxy-10, 13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]ethanesulfonic acid
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Identifiers |
CAS Registry Number
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516-50-7 N |
ChEBI |
CHEBI:9410 Y |
ChEMBL |
ChEMBL412272 Y |
ChemSpider |
2015539 Y |
InChI
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InChI=1S/C26H45NO6S/c1-16(4-9-24(30)27-12-13-34(31,32)33)20-7-8-21-19-6-5-17-14-18(28)10-11-25(17,2)22(19)15-23(29)26(20,21)3/h16-23,28-29H,4-15H2,1-3H3,(H,27,30)(H,31,32,33)/t16-,17-,18-,19+,20-,21+,22+,23+,25+,26-/m1/s1 Y
Key: AWDRATDZQPNJFN-VAYUFCLWSA-N Y
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InChI=1/C26H45NO6S/c1-16(4-9-24(30)27-12-13-34(31,32)33)20-7-8-21-19-6-5-17-14-18(28)10-11-25(17,2)22(19)15-23(29)26(20,21)3/h16-23,28-29H,4-15H2,1-3H3,(H,27,30)(H,31,32,33)/t16-,17-,18-,19+,20-,21+,22+,23+,25+,26-/m1/s1
Key: AWDRATDZQPNJFN-VAYUFCLWBR
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Jmol-3D images |
Image |
PubChem |
2733768 |
SMILES
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C[C@H](CCC(=O)NCCS(=O)(=O)O)[C@H]1CC[C@@H]2[C@@]1([C@H](C[C@H]3[C@H]2CC[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C
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Properties |
Chemical formula
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C26H44NO6S- |
Molar mass |
498.70 g/mol |
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
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N verify (what is: Y/N?) |
Infobox references |
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Taurodeoxycholic acid is a bile acid.
UpToDate Contents
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English Journal
- Celecoxib and tauro-ursodeoxycholic acid co-treatment inhibits cell growth in familial adenomatous polyposis derived LT97 colon adenoma cells.
- van Heumen BW, Roelofs HM, Te Morsche RH, Marian B, Nagengast FM, Peters WH.SourceDepartment of Gastroenterology and Hepatology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands. b.vanheumen@mdl.umcn.nl
- Experimental cell research.Exp Cell Res.2012 Apr 15;318(7):819-27. Epub 2012 Feb 14.
- Chemoprevention would be a desirable strategy to avoid duodenectomy in patients with familial adenomatous polyposis (FAP) suffering from duodenal adenomatosis. We investigated the in vitro effects on cell proliferation, apoptosis, and COX-2 expression of the potential chemopreventives celecoxib and
- PMID 22366264
- Influenza A viral replication is blocked by inhibition of the inositol-requiring enzyme 1 (IRE1) stress pathway.
- Hassan IH, Zhang MS, Powers LS, Shao JQ, Baltrusaitis J, Rutkowski DT, Legge K, Monick MM.SourceDepartment of Internal Medicine, University of Iowa, Iowa City, Iowa 52242, USA. ihab-hassan@uiowa.edu
- The Journal of biological chemistry.J Biol Chem.2012 Feb 10;287(7):4679-89. Epub 2011 Dec 22.
- Known therapies for influenza A virus infection are complicated by the frequent emergence of resistance. A therapeutic strategy that may escape viral resistance is targeting host cellular mechanisms involved in viral replication and pathogenesis. The endoplasmic reticulum (ER) stress response, also
- PMID 22194594
Japanese Journal
- Strain Differences in Deconjugation of Bile Acids in Bifidobacterium pseudocatenulatum Isolates
- MARIAM Rezaei Sabet,YAP Keng Wai,LIM Long Chang,KHARIDAH Muhammad,SHUHAIMI Mustafa,ABDULLAH Sipat,ALI Abdul Manaf,ATIOAH Abdullah Nur,YAZID Abdul Manap
- Bioscience and microflora 23(2), 93-98, 2004-04-01
- … Six isolates of bifidobacteria with higher tolerance to 4.0% of bile were further evaluated for their ability to deconjugate different types of bile acids namely taurocholic acid (TC), glycocholic acid (GC), taurochenodeoxycholic acid (TCDC), glycochenodeoxycholic acid (GCDC), taurodeoxycholic acid (TDC), and glycodeoxycholic acid (GDC). …
- NAID 10027995027
- Triacylglycerol Lipase Participates in the Formation of n-Hexanal in Alfalfa Seedlings
- Uno Chiharu,Hara Takashi,Joh Toshio
- Food science and technology research 9(2), 185-189, 2003-05-01
- … Taurodeoxycholic acid sodium salt (TDCA), an inhibitor of triacylglycerol lipase, inhibited the formation of n-hexanal by 36%. …
- NAID 10012000683
- Influence of Various Bile Acids on the Metabolism of Glycyrrhizin and Glycyrrhetic Acid by Ruminococcus sp. PO1-3 of Human Intestinal Bacteria
- Akao Taiko
- Biological & pharmaceutical bulletin 22(8), 787-793, 1999-08-15
- … PO1-3,an intestinal bacterium isolated from human feces, metabolized glycyrrhizin (GL) to glycyrrhetic acid (GA) and GA to 3-oxo-glycyrrhetic acid (3-oxo-GA) and possessed GL β-D-glucuronidase and 3β-hydroxysteroid dehydrogenase (3β-HSD) involved in the metabolism of GL. …
- NAID 110003639762
Related Links
- Buy Taurodeoxycholic Acid, Sodium Salt (CAS 1180-95-6), a product for proteomics research, from Santa Cruz Biotechnology. MF: C26H44NO6S Na, MW: 521.7 ... Taurodeoxycholic Acid, Sodium Salt is a detergent useful for the ...
- Record Information Version 3.5 Creation Date 2005-11-16 08:48:42 -0700 Update Date 2013-05-29 13:29:35 -0600 HMDB ID HMDB00896 Secondary Accession Numbers HMDB04011 Metabolite Identification Common Name
★リンクテーブル★
[★]
タウロデオキシコール酸
- 関
- taurodeoxycholic acid
[★]
- 英
- taurodeoxycholic acid、taurodeoxycholate