瞼板腺
- 関
- meibomian gland
WordNet
- of or relating to or near the tarsus of the foot; "tarsal bones"
- any bone of the tarsus (同)tarsal_bone
- any of various organs that synthesize substances needed by the body and release it through ducts or directly into the bloodstream (同)secretory organ, secretor, secreter
PrepTutorEJDIC
- 足首の / 足根骨
- (生物体内の)腺(せん)
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/08/19 10:43:49」(JST)
[Wiki en表示]
Meibomian gland |
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Front of left eye with eyelids separated to show medial canthus and openings of tarsal (meibomian) glands. |
Latin |
glandulae tarsales |
Gray's |
subject #227 1026 |
MeSH |
Meibomian+glands |
The meibomian glands (or tarsal glands) are a special kind of sebaceous gland at the rim of the eyelids inside the tarsal plate, responsible for the supply of meibum, an oily substance that prevents evaporation of the eye's tear film. Meibum prevents tear spillage onto the cheek, trapping tears between the oiled edge and the eyeball, and makes the closed lids airtight.[1] There are approximately 50 glands on the upper eyelids and 25 glands on the lower eyelids. The glands are named after Heinrich Meibom (1638–1700), a German physician.
Contents
- 1 Meibum
- 2 Dysfunction
- 3 See also
- 4 References
- 5 External links
Meibum[edit source | edit]
Lipids[edit source | edit]
Lipids are the major components of meibum (also known as "meibomian gland secretions"). The term "meibum" was originally introduced by Nicolaides et al. in 1981.[2] The biochemical composition of meibum is extremely complex and very different from that of sebum. Lipids are universally recognized as major components of human and animal meibum. Recently, an update on the composition of human meibum and on the structures of various positively identified meibomian lipids was published.[3] Currently, the most sensitive and informative approach to lipidomic analysis of meibum is mass spectrometry in combination with liquid chromatography.[4]
Proteins[edit source | edit]
In humans, more than 90 different proteins have been identified in meibomian gland secretions.[5]
Dysfunction[edit source | edit]
Dysfunctional meibomian glands often cause dry eyes, one of the more common eye conditions. They may also cause blepharitis, as the dry eyeball rubs off small pieces of skin from the eyelid, which may get infected. Inflammation of the meibomian glands (also known as meibomitis, meibomian gland dysfunction, or posterior blepharitis) causes the glands to be obstructed by thick waxy secretions. Besides leading to dry eyes, the obstructions can be degraded by bacterial lipases, resulting in the formation of free fatty acids, which irritate the eyes and sometimes cause punctate keratopathy.
See also[edit source | edit]
- List of specialized glands within the human integumentary system
References[edit source | edit]
- ^ "eye, human." Encyclopædia Britannica. Encyclopaedia Britannica Ultimate Reference Suite. Chicago: Encyclopædia Britannica, 2010.
- ^ Nicolaides N, Kaitaranta JK, Rawdah TN, Macy JI, Boswell FM 3rd, Smith RE. "Meibomian gland studies: comparison of steer and human lipids." Invest Ophthalmol Vis Sci. 1981 Apr;20(4):522-536. PMID 7194326.
- ^ Butovich IA (November 2009). "The Meibomian puzzle: combining pieces together". Prog Retin Eye Res 28 (6): 483–498. doi:10.1016/j.preteyeres.2009.07.002. PMID 19660571.
- ^ Butovich IA. "Lipidomic analysis of human meibum using HPLC-MSn." Methods Mol Biol. 2009;579:221-246. PMID 19763478.
- ^ Tsai PS, Evans JE, Green KM, Sullivan RM, Schaumberg DA, Richards SM, Dana MR, Sullivan DA. "Proteomic analysis of human meibomian gland secretions." Br J Ophthalmol. 2006 March;90(3):372-7. doi:10.1136/bjo.2005.080846 PMID 16488965.
External links[edit source | edit]
- synd/541 at Who Named It?
Head and neck anatomy – accessory visual structures (TA 15.2.7, TH H3.11.08.6, GA 10.1021)
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Eyelid |
- Tarsus
- Medial palpebral ligament
- Epicanthic fold
- Meibomian gland
- Ciliary glands
- Eyelash
- Palpebral fissure
- Canthus
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Lacrimal apparatus |
- Lacrimal lake
- Lacrimal gland
- Lacrimal canaliculi
- Lacrimal punctum
- Lacrimal papilla
- Nasolacrimal duct
- Lacrimal sac
- Lacrimal caruncle
- Krause's glands
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Other |
- Periorbita
- Orbital septum
- Tenon's capsule
- Suspensory ligament of eyeball
- Conjunctiva (Plica semilunaris)
- Extraocular muscles (Trochlea of superior oblique)
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anat (g/a/p)/phys/devp/prot
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proc, drug (S1A/1E/1F/1L)
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Histology: Epithelial tissue (TH H2.00.02)
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Epithelial cells |
- Columnar epithelial cell
- Cuboidal epithelial cell
- Squamous epithelial cell
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Surface epithelium |
- Simple squamous epithelium
- Simple cuboidal epithelium
- Simple columnar epithelium
- Pseudostratified columnar epithelium
- Stratified squamous epithelium
- Stratified cuboidal epithelium
- Stratified columnar epithelium
- Transitional epithelium/Urothelium
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Gland/
glandular epithelium |
Classification
(exocrine,
endocrine) |
Mechanism |
- Merocrine
- Apocrine
- Holocrine
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Shape |
- Tubular gland
- Alveolar gland
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Secretion |
- Serous glands
- Mucous glands
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Components |
- Myoepithelial cell
- Serous demilune
- Ducts: Interlobar duct
- Interlobular duct
- Intralobular duct
- Striated duct
- Intercalated duct
- Acinus/Lobe
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- See also
- Template:Epithelial neoplasms
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UpToDate Contents
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English Journal
- Ex vivo heat retention of different eyelid warming masks.
- Lacroix Z1, Léger S1, Bitton E2.
- Contact lens & anterior eye : the journal of the British Contact Lens Association.Cont Lens Anterior Eye.2015 Jun;38(3):152-6. doi: 10.1016/j.clae.2015.01.005. Epub 2015 Feb 27.
- PURPOSE: Meibomian gland dysfunction (MGD) appears to be the most common cause of evaporative dry eye, in which the meibum has an altered chemical structure that increases its melting point. Eyelid warming masks slowly transfer heat, preferably between 40 and 45°C to the inner meibomian glands, in
- PMID 25735560
- Evaluation of dry eye and meibomian gland dysfunction with meibography in patients with rosacea.
- Palamar M1, Degirmenci C, Ertam I, Yagci A.
- Cornea.Cornea.2015 May;34(5):497-9. doi: 10.1097/ICO.0000000000000393.
- PURPOSE: To evaluate the dry eye tests and meibography of patients with ocular rosacea.METHODS: Thirty-six eyes of 18 patients with ocular rosacea (group 1) and 38 eyes of 19 healthy individuals (group 2) were enrolled. Besides full-eye examination, corneal and conjunctival fluorescein staining and
- PMID 25826323
- Increased Tear Fluid Production as a Compensatory Response to Meibomian Gland Loss: A Multicenter Cross-sectional Study.
- Arita R1, Morishige N2, Koh S3, Shirakawa R4, Kawashima M5, Sakimoto T6, Suzuki T7, Tsubota K8.
- Ophthalmology.Ophthalmology.2015 May;122(5):925-33. doi: 10.1016/j.ophtha.2014.12.018. Epub 2015 Jan 24.
- PURPOSE: To compare tear film parameters as well as meibomian gland morphologic features and function among patients with meibomian gland dysfunction (MGD), those with non-Sjögren syndrome aqueous-deficient dry eye (non-SS ADDE), those with non-SS ADDE and MGD, and normal subjects.DESIGN: Multicent
- PMID 25626757
Japanese Journal
- Identification of 20-hydroxyecdysone-inducible Genes from Larval Brain of the Silkworm, Bombyx mori, and Their Expression Analysis
- 低い総線量の放射線治療により症状が軽減した下垂体性副腎皮質機能亢進症の犬の1例
- 犬における腎細胞癌の播種性転移に伴う肥大性骨症 : 症例報告(病理学)
- The journal of veterinary medical science 69(2), 209-212, 2007-02-25
- NAID 110006201241
Related Links
- tarsal gland n. Any of the branched sebaceous glands located in the tarsus of the eyelid. tarsal gland any one of numerous modified sebaceous glands on the ... Tarsal: When I began deer hunting there was a widespread ...
- The tarsal gland, arguably the most important gland in deer communication, is found on bucks and does. Each hair is associated with an enlarged sebaceous or “fat” gland that secretes an oily material that coats the hair.
★リンクテーブル★
[★]
- 英
- tarsal gland
- 関
- マイボーム腺 meibomian gland
眼瞼縁の分泌腺
臨床関連
- 霰粒腫:瞼板腺の慢性肉芽性炎症で、瞼板腺の分泌物貯留によって起こる。
[★]
- 関
- tarsi、tarsus