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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/09/18 10:00:23」(JST)
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- 1. 再発性および難治性の急性前骨髄球性白血病の治療 treatment of relapsed or refractory acute promyelocytic leukemia in adults
English Journal
- Tamibarotene in patients with acute promyelocytic leukaemia relapsing after treatment with all-trans retinoic acid and arsenic trioxide.
- Sanford D1, Lo-Coco F2, Sanz MA3,4, Di Bona E5, Coutre S6, Altman JK7, Wetzler M8, Allen SL9, Ravandi F1, Kantarjian H1, Cortes JE1.
- British journal of haematology.Br J Haematol.2015 Nov;171(4):471-7. doi: 10.1111/bjh.13607. Epub 2015 Jul 24.
- Treatment of acute promyelocytic leukaemia (APL) with arsenic trioxide (ATO) and all-trans retinoic acid (ATRA) is highly effective first-line therapy, although approximately 5-10% of patients relapse. Tamibarotene is a synthetic retinoid with activity in APL patients who relapse after chemotherapy
- PMID 26205361
- Activation of AMP-activated protein kinase by retinoic acid sensitizes hepatocellular carcinoma cells to apoptosis induced by sorafenib.
- Ishijima N1, Kanki K1, Shimizu H1, Shiota G1.
- Cancer science.Cancer Sci.2015 May;106(5):567-75. doi: 10.1111/cas.12633. Epub 2015 Mar 9.
- To improve the outcome of cancer chemotherapy, strategies to enhance the efficacy of anticancer drugs are required. Sorafenib is the only drug to prolong overall survival of the patients with hepatocellular carcinoma (HCC), however, the outcome is still not satisfactory. Retinoids, vitamin A derivat
- PMID 25683251
- Activity analysis and preliminary inducer screening of the chicken DAZL gene promoter.
- Zhang L1, Zhu R2, Zuo Q3, Li D4, Lian C5, Tang B6, Xiao T7, Zhang Y8, Li B9.
- International journal of molecular sciences.Int J Mol Sci.2015 Mar 23;16(3):6595-605. doi: 10.3390/ijms16036595.
- This study was aimed at identifying the active control area of chicken DAZL gene core promoter, to screen optimum inducers of the DAZL gene, thus to enhance the differentiation of embryonic stem cells into spermatogonial stem cells. Fragments of chicken DAZL gene promoter were cloned into fluorescen
- PMID 25807265
Japanese Journal
- 急性骨髄性白血病の分子標的薬 : 現状と今後の展望 (特集 血液疾患の分子標的薬 : 進化する血液疾患治療研究の最新動向) -- (治療研究)
- 高後 裕,稲村 純季,進藤 基博
- 日本臨床 72(6), 1063-1067, 2014-06
- NAID 40020100518
- 成人急性前骨髄球性白血病の治療
- 藤田 浩之
- 臨床血液 55(10), 1817-1826, 2014
- NAID 130004696074
- Synthesis of Am80 (Tamibarotene) Prodrug Candidates, Congeners and Metabolites
- Muratake Hideaki,Amano Yohei,Toda Takahiro [他],Sugiyama Kiyoshi,Shudo Koichi
- Chemical and Pharmaceutical Bulletin 61(8), 846-852, 2013
- … Compound 1 (IT-M-07000) was previously reported as a candidate prodrug of Am80 (Tamibarotene; …
- NAID 130003360816
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- タミバロテン（アムノレイク）はトレチノインに続く2つ目のレチノイドとして2005年に承認を受けた抗がん剤で、白血病の中でも特殊な急性前骨髄球性白血病（APL）の治療に用いられます。
- 1. Drugs Today (Barc). 2007 Aug;43(8):563-8. Tamibarotene. Miwako I(1), Kagechika H. Author information: (1)R&R Inc., Tokyo, Japan. Tamibarotene is a new synthetic retinoid drug recently approved for relapsed or ...
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