syngenic

• 同質遺伝子的な、シンジェニックな

関

isogenic、isogenically

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2017/08/28 19:51:29」(JST)

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The word "syngenic" or "syngeneic" (from the Greek word for a relative) means genetically identical, or sufficiently identical and immunologically compatible as to allow for transplantation. For example, it may be used for something transplanted from an identical twin. When the cells are collected from the same patient on whom they will be used, it is called autologous and when collected from identical individuals, it is referred to as syngeneic. A syngeneic graft is known as an isograft.

It is contrasted with Autotransplantation (from one part of the body to another in the same person), allotransplantation (from other individual of same species), and xenotransplantation (from other species).

A tumor isolated from an organism and transplanted in its syngeneic organism elicits an immune reaction leading to rejection, whereas a normal transplanted tissue won't. This signifies that tumor cells show antigens which are completely new or modified. This forms the basis of Tumor Specific Transplantation Antigens(TSTA) or Tumor Associated Transplant Antigens(TATA).

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• 1. 正常な加齢 normal aging

English Journal

• Human Embryonic Stem Cells Prevent T-Cells Activation by Suppressing Dendritic Cells Function Via TGF-Beta Signaling Pathway.

• Leshansky L1, Aberdam D, Itskovitz-Eldor J, Berrih-Aknin S.
• Stem cells (Dayton, Ohio).Stem Cells.2014 Sep 3. doi: 10.1002/stem.1833. [Epub ahead of print]
• Human embryonic stem cells (hESCs) represent a potential source of transplantable cells for regenerative medicine, but development of teratoma even in syngenic recipients represents a critical obstacle to safe stem cell-based therapies. We hypothesized that hESCs escape the immune surveillance by re
• PMID 25186014

• Combination of BMP2 and MSCs Significantly Increases Bone Formation in the Rat Arterio-Venous Loop Model.

• Buehrer G1, Balzer A, Arnold I, Beier JP, Koerner C, Bleiziffer O, Brandl A, Weis C, Horch RE, Kneser U, Arkudas A.
• Tissue engineering. Part A.Tissue Eng Part A.2014 Aug 19. [Epub ahead of print]
• Introduction: In this study the induction of bone formation in an axially vascularized bone matrix using mesenchymal stem cells (MSCs) and application of BMP2 was analyzed in the arteriovenous loop model. Materials and Methods: An arteriovenous loop was created in the medial thigh of 42 rats and pla
• PMID 25135080

• Prolonged survival upon ultrasound-enhanced doxorubicin delivery in two syngenic glioblastoma mouse models.

• Kovacs Z1, Werner B2, Rassi A3, Sass JO3, Martin-Fiori E2, Bernasconi M4.
• Journal of controlled release : official journal of the Controlled Release Society.J Control Release.2014 Aug 10;187:74-82. doi: 10.1016/j.jconrel.2014.05.033. Epub 2014 May 27.
• Glioblastoma multiforme (GBM) is the most common and most aggressive malignant primary brain tumor in humans with a very poor prognosis. Chemotherapeutical treatment of GBMs is limited by the blood-brain barrier (BBB). This physical and metabolic barrier separates the blood from the brain parenchyma
• PMID 24878186

Japanese Journal

• 化学療法抵抗性卵巣癌の局所免疫の解析に基づいた,がん免疫逃避を標的とした新規治療戦略(シンポジウム2(腫瘍) 難治性卵巣癌の克服を目指して,第66回日本産科婦人科学会学術講演会講演要旨)

• 日本産科婦人科學會雜誌 66(11), 2777-2791, 2014-11-01
• NAID 110009872637

• Transplantation of a Mammary Stromal Cell Line into a Mammary Fat Pad : Development of the Site-Specific in Vivo Analysis System for Mammary Stromal Cells

• Bioscience, biotechnology, and biochemistry 75(3), 550-555, 2011-03-23
• NAID 10028201934

• An embryo-specific expressing TGF-β family protein, growth-differentiation factor 3 (GDF3), augments progression of B16 melanoma

• Journal of Experimental & Clinical Cancer Research 29, 135, 2010-10-15
• NAID 120002603326

Related Links

• Syngenic - Wikipedia, the free encyclopedia

The word "syngenic" or "syngeneic" (from the Greek word for a relative) means genetically identical, or sufficiently identical and immunologically compatible as to allow for transplantation. For example, it may be used for something transplanted ...

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リンク元	「同質遺伝子的」「isogenic」「isogenically」「シンジェニック」

「同質遺伝子的」

　　[★]

英

isogenic、syngenic、isogenically

関

アイソジェニック、シンジェニック

「isogenic」

　　[★]

• 同質遺伝子的な、アイソジェニックな

関

isogenically、syngenic

「isogenically」

　　[★]

• 同質遺伝子的に

関

isogenic、syngenic

「シンジェニック」

　　[★]

英

syngenic

関

同質遺伝子的