English Journal

Transforming potential and matrix stiffness co-regulate confinement sensitivity of tumor cell migration.

Pathak A, Kumar S.SourceDepartment of Bioengineering, University of California, Berkeley, CA 94720-1762, USA. skumar@berkeley.edu.
Integrative biology : quantitative biosciences from nano to macro.Integr Biol (Camb).2013 Aug 22;5(8):1067-75. doi: 10.1039/c3ib40017d.
It is now well established that tumor cell invasion through tissue is strongly regulated by the microstructural and mechanical properties of the extracellular matrix (ECM). However, it remains unclear how these physical microenvironmental inputs are jointly processed with oncogenic lesions to drive
PMID 23832051

Efficacy of Humanized Carbapenem Exposures against New Delhi Metallo-β-Lactamase (NDM-1)-Producing Enterobacteriaceae in a Murine Infection Model.

Wiskirchen DE, Nordmann P, Crandon JL, Nicolau DP.SourceUniversity of Saint Joseph, School of Pharmacy, Hartford, Connecticut, USA.
Antimicrobial agents and chemotherapy.Antimicrob Agents Chemother.2013 Aug;57(8):3936-40. doi: 10.1128/AAC.00708-13. Epub 2013 Jun 3.
Enterobacteriaceae producing the novel carbapenemase New Delhi metallo-β-lactamase (NDM-1) are emerging worldwide. While these organisms often display high levels of in vitro resistance to multiple antibiotics, in vivo efficacy data are lacking. Here, the activities of humanized ertapenem and dorip
PMID 23733463

The effect of fibroblast activation on vascularization in transplanted pancreatic islets.

Liu D, Xiao H, Du C, Luo S, Li D, Pan L.SourceDepartment of Hepatobiliary Surgery, The First Affiliated Hospital of Chong Qing Medical University, Chong Qing, PR China.
The Journal of surgical research.J Surg Res.2013 Jul;183(1):450-6. doi: 10.1016/j.jss.2012.12.044. Epub 2013 Jan 20.
BACKGROUND: Insufficient revascularization of transplanted pancreatic islets is an important reason why the long-term effects of pancreatic islet transplantation on type I diabetes patients have been so limited. The goal of this study was to investigate the role of fibroblasts (FBs) activated by tum
PMID 23369362