- 日
- 関
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/07/23 14:01:47」(JST)
[Wiki en表示]
Sulfadimethoxine
|
|
| Systematic (IUPAC) name |
| 4-Amino-N-(2,6-dimethoxypyrimidin-4-yl)benzenesulfonamide |
| Clinical data |
| AHFS/Drugs.com |
FDA Professional Drug Information |
| Legal status |
? |
| Identifiers |
| CAS number |
122-11-2 Y |
| ATC code |
J01ED02 QJ01EQ09 QP51AG02 |
| PubChem |
CID 5323 |
| DrugBank |
DB06150 |
| ChemSpider |
5132 Y |
| UNII |
30CPC5LDEX Y |
| KEGG |
D01142 Y |
| ChEBI |
CHEBI:32161 Y |
| ChEMBL |
CHEMBL62193 Y |
| Chemical data |
| Formula |
C12H14N4O4S |
| Mol. mass |
310.33 g/mol |
SMILES
- COc1cc(nc(n1)OC)NS(=O)(=O)c2ccc(cc2)N
|
InChI
-
InChI=1S/C12H14N4O4S/c1-19-11-7-10(14-12(15-11)20-2)16-21(17,18)9-5-3-8(13)4-6-9/h3-7H,13H2,1-2H3,(H,14,15,16) Y
Key:ZZORFUFYDOWNEF-UHFFFAOYSA-N Y
|
| Y (what is this?) (verify) |
Sulfadimethoxine (trade name Di-Methox, Albon) is a sulfonamide antibiotic. Albon is produced by Pfizer Animal Health and is available as an oral suspension, tablet or bolus. It is used to treat many infections including treatment of respiratory, urinary tract, enteric, and soft tissue infections.[5] It is most frequently used in veterinary medicine. Sulfadimethoxine inhibits bacterial synthesis of folic acid (pteroylglutamic acid) from para-aminobenzoic acid. It is also commonly used for the treatment of coccidiosis in many species.[1]
Sulfadimethoxine is approved in Russia for use in humans, including children, and has been successfully used there for more than 35 years.[2] It is widely available in Russia as an over-the-counter drug manufactured by a number of Russian pharmaceutical companies.
Contents
- 1 Side Effects
- 2 Uses
- 3 Actions
- 4 Notes
- 5 External links
Side Effects
Some side effects include:
- Redness of the eye[3]
- Discharge from the eye
- Other symptoms related to the eye
- Bleeding
- Vomiting and diarrhea
- Increased thirst is common[4]
- Incessant itch
Animals should be kept well hydrated to prevent the formation of sulfa crystals in the animal's urine.[6]
Uses
It can be used for:[5]
- metritis
- tonsillitis
- pharyngitis
- pneumonia
- pyometra
- anal gland infections
- dermatitis
- wounds and abscesses
- enteritis
- salmonellosis
- enteritis associated with coccidiosis in dogs
Actions
It has been shown to be effective against streptococci, klebsiella, proteus, shigella, staphylococci, escherichia, and salmonella.
Notes
- ^ [1]
- ^ ru:Сульфадиметоксин
- ^ [2]
- ^ [3]
- ^ [4]
External links
- Albon Oral Suspension product overview
- Albon Tablets product overview
- Albon Bolus product overview
- Coccidia Treatment
- Sulfadimethoxine
|
Antibacterials: nucleic acid inhibitors (J01E, J01M)
|
|
Antifolates
(inhibits
purine metabolism,
thereby inhibiting
DNA and RNA synthesis) |
| DHFR inhibitor |
- 2,4-Diaminopyrimidine
- Trimethoprim#
- Brodimoprim
- Tetroxoprim
- Iclaprim†
|
|
Sulfonamides
(DHPS inhibitor) |
Short-
acting |
- Sulfaisodimidine
- Sulfamethizole
- Sulfadimidine
- Sulfapyridine
- Sulfafurazole
- Sulfanilamide
- Sulfathiazole
- Sulfathiourea
|
|
Intermediate-
acting |
- Sulfamethoxazole
- Sulfadiazine#
- Sulfamoxole
|
|
Long-
acting |
- Sulfadimethoxine
- Sulfadoxine
- Sulfalene
- Sulfametomidine
- Sulfametoxydiazine
- Sulfamethoxypyridazine
- Sulfaperin
- Sulfamerazine
- Sulfaphenazole
- Sulfamazone
|
|
| Other/ungrouped |
- Sulfacetamide
- Sulfadicramide
- Sulfametrole
|
|
|
| Combinations |
- Trimethoprim/sulfamethoxazole#
|
|
|
Topoisomerase
inhibitors/
quinolones/
(inhibits
DNA replication) |
| 1st g. |
- Cinoxacin‡
- Flumequine
- Nalidixic acid
- Oxolinic acid
- Pipemidic acid
- Piromidic acid
- Rosoxacin
|
|
Fluoro-
quinolones |
| 2nd g. |
- Ciprofloxacin#
- Enoxacin‡
- Fleroxacin‡
- Lomefloxacin
- Nadifloxacin
- Ofloxacin
- Norfloxacin
- Pefloxacin
- Rufloxacin
|
|
| 3rd g. |
- Balofloxacin
- Grepafloxacin‡
- Levofloxacin
- Pazufloxacin
- Sparfloxacin‡
- Temafloxacin‡
- Tosufloxacin
|
|
| 4th g. |
- Besifloxacin
- Clinafloxacin†
- Garenoxacin
- Gemifloxacin
- Moxifloxacin
- Gatifloxacin‡
- Sitafloxacin
- Trovafloxacin‡/Alatrofloxacin‡
- Prulifloxacin
|
|
| Vet. |
- Danofloxacin
- Difloxacin
- Enrofloxacin
- Ibafloxacin
- Marbofloxacin
- Orbifloxacin
- Pradofloxacin
- Sarafloxacin
|
|
| Related (DG) |
- Aminocoumarins: Novobiocin
|
|
|
|
Anaerobic DNA
inhibitors |
| Nitro- imidazole derivatives |
- Metronidazole#
- Tinidazole
- Ornidazole
|
|
| Nitrofuran derivatives |
- Nitrofurantoin#
- Furazolidone‡
- Nifurtoinol
|
|
|
| RNA synthesis |
Rifamycins/
RNA polymerase |
- Rifampicin#
- Rifabutin
- Rifapentine
- Rifaximin
|
|
|
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
|
|
|
gr+f/gr+a (t)/gr-p (c)/gr-o
|
drug (J1p, w, n, m, vacc)
|
|
|
|
English Journal
- pH-induced phase transition control of thermoresponsive nano-micelles possessing outermost surface sulfonamide moieties.
- Nakayama M, Kawahara Y, Akimoto J, Kanazawa H, Okano T.SourceInstitute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University (TWIns), Shinjuku, Tokyo 162-8666, Japan.
- Colloids and surfaces. B, Biointerfaces.Colloids Surf B Biointerfaces.2012 Nov 1;99:12-9. Epub 2011 Sep 19.
- Diblock copolymer comprising thermoresponsive poly(N-isopropylacrylamide-co-N,N-dimethylacrylamide) (PIPAAm-co-DMAAm) and hydrophobic poly(benzyl methacrylate) blocks was prepared by reversible addition-fragmentation chain transfer radical polymerization. Terminal functionalization of thermoresponsi
- PMID 21974909
- Antimicrobial susceptibility pattern of Flavobacterium columnare isolates collected worldwide from 17 fish species.
- Declercq AM, Boyen F, Van den Broeck W, Bossier P, Karsi A, Haesebrouck F, Decostere A.SourceDepartment of Morphology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.
- Journal of fish diseases.J Fish Dis.2012 Sep 7. doi: 10.1111/j.1365-2761.2012.01410.x. [Epub ahead of print]
- Flavobacterium columnare is the causative agent of columnaris disease in diverse fish species worldwide. Although columnaris is an important disease, the antimicrobial susceptibility pattern of F. columnare is not well studied. Thus, the purpose of this study was to test the in vitro antimicrobial
- PMID 22957716
Japanese Journal
- Pathology: Preventive effects of calcitriol on the development of capsular invasive carcinomas in a rat two-stage thyroid carcinogenesis model
- Kemmochi Sayaka,Fujimoto Hitoshi,Woo Gye-Hyeong [他]
- 日本獣醫學会会誌 73(5), 655-664, 2011-05
- NAID 40018864929
- Drug pH-Sensitive Release in Vitro and Targeting Ability of Polyamidoamine Dendrimer Complexes for Tumor Cells
- Liu Dan,Hu Haiyang,Zhang Jie,Zhao Xiuli,Tang Xing,Chen Dawei
- CHEMICAL & PHARMACEUTICAL BULLETIN 59(1), 63-71, 2011
- … In this study, a pH-sensitive diblock copolymer of poly(methacryloyl sulfadimethoxine) (PSD) and polyethylene glycol (PEG) modified by lactose (LA-PEG-b-PSD) was synthesized. …
- NAID 130000405490
Related Links
- [Sulfadimethoxine] [122-11-2] | 価格や在庫、物性値などの詳細情報ページです。 ... ・川口の在庫は即日，つくばの在庫は2〜3日以内の出荷となります。・詳細につきましては，お手数ですが営業部までお問い合わせください。
- Sulfadimethoxine, Sulfadimethoxine Manufacturers & Suppliers Directory - Find here Sulfadimethoxine Traders, Sulfadimethoxine Producers, Sulfadimethoxine Exporters, Sulfadimethoxine Wholesalers, Sulfadimethoxine Welcome ...
Related Pictures
★リンクテーブル★
[★]
- 英
- sulfadimethoxine
- 商
- アプシード、ジメキシン、スルキシン