Evaluation of clinical trial of atopic dermatitis by a topical cream containing the extracts from photosynthetic bacteria, Rhodobacter sphaeroides.
Kim NY1, Cho JS, Lee HY.
AMB Express.AMB Express.2015 Dec;5(1):133. doi: 10.1186/s13568-015-0133-4. Epub 2015 Aug 12.
The photosynthetic bacteria Rhodobacter sphaeroides has been studied as a functional food source; however, in this clinical study, we report for the first time its use as a treatment for atopic dermatitis. Topical cream containing 10% (v/v) extract was demonstrated to have the ability to reduce skin
TLR4 antagonist attenuates atherogenesis in LDL receptor-deficient mice with diet-induced type 2 diabetes.
Lu Z1, Zhang X1, Li Y1, Lopes-Virella MF2, Huang Y3.
Immunobiology.Immunobiology.2015 Nov;220(11):1246-54. doi: 10.1016/j.imbio.2015.06.016. Epub 2015 Jun 30.
Although a large number of studies have well documented a key role of toll-like receptor (TLR)4 in atherosclerosis, it remains undetermined if TLR4 antagonist attenuates atherogenesis in mouse model for type 2 diabetes. In this study, we induced type 2 diabetes in low-density lipoprotein receptor-de
Effects of the protonophore carbonyl-cyanide m-chlorophenylhydrazone on intracytoplasmic membrane assembly in Rhodobacter sphaeroides.
Woronowicz K1, Olubanjo OB1, Sha D1, Kay JM1, Niederman RA2.
Biochimica et biophysica acta.Biochim Biophys Acta.2015 Oct;1847(10):1119-28. doi: 10.1016/j.bbabio.2015.06.002. Epub 2015 Jun 5.
The effect of carbonyl-cyanide m-chlorophenyl-hydrazone (CCCP) on intracytoplasmic membrane (ICM) assembly was examined in the purple bacterium Rhodobacter sphaeroides. CCCP blocks generation of the electrochemical proton gradient required for integral membrane protein insertion. ICM formation was i