WordNet

susceptible of solution or of being solved or explained; "the puzzle is soluble"
(of a substance) capable of being dissolved in some solvent (usually water)
a white insoluble fibrous protein formed by the action of thrombin on fibrinogen when blood clots; it forms a network that traps red cells and platelets
a simple compound whose molecules can join together to form polymers

PrepTutorEJDIC

溶解できる / 解決できる
(凝固血液中の)線維素,フィブリン
単量体(異種の分子と反応し重合体を構成する)

UpToDate Contents

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1. 止血の概要overview of hemostasis [show details]
… from adjacent fibrin monomers that have been crosslinked by activated factor XIII Plasmin also cleaves factor XIIIa, but not factor XIII, leading to reduced fibrin crosslinking .… Thrombin converts fibrinogen from a soluble plasma protein into an insoluble fibrin clot (tested in the in vitro thrombin time [TT]).…
2. 局所止血剤および生体組織接着剤の概要overview of topical hemostatic agents and tissue adhesives [show details]
… combination with fibrin sealant, drain output volume was also reduced . Cyanoacrylate tissue adhesives octyl-2-cyanoacrylate (eg, Dermabond) and butyl-2-cyanoacrylate (eg, Histoacryl) are liquid monomers that change… Ostene – Ostene is a wax-like compound of a water-soluble alkaline oxide copolymer that occludes bleeding vessels in bone similar to bone wax,…
3. フィブリノゲンの異常disorders of fibrinogen [show details]
…adjacent fibrin monomer , forming a two-molecule-thick strand or protofibril. This is followed by longitudinal growth (D-D contact between adjacent fibrin monomers) and branching to form the final fibrin network… between fibrin clot formation and fibrinolysis determines whether the clinical manifestations include bleeding, thrombosis, both, or neither. Formation of fibrin – Fibrinogen is the soluble precursor…
4. 乳児や小児の播種性血管内凝固disseminated intravascular coagulation in infants and children [show details]
…Fibrinolysis – Fibrin formation activates the fibrinolytic pathway, which produces plasmin that cleaves fibrinogen and fibrin, thereby generating fibrin degradation products (FDPs). FDPs interfere with fibrin polymerization… Investigational therapy – Recombinant human soluble thrombomodulin (ART-123),…
5. フィブリンシーラントfibrin sealants [show details]
…Evarrest) and pads (eg, Fibrin Pad) that are composed of fibrin sealant combined with other hemostatic agents (eg, polyglactin, oxidized regenerated cellulose [ORC]) . A spray-dried fibrin sealant formulation …

English Journal

Capsule Commentary on Rivera-Caravaca et al., Soluble Fibrin Monomer Complex and Prediction of Cardiovascular Events in Atrial Fibrillation: The Observational Murcia Atrial Fibrillation Project.

Samuelson Bannow BT1.
Journal of general internal medicine.J Gen Intern Med.2018 Jan 29. doi: 10.1007/s11606-018-4320-2. [Epub ahead of print]
PMID 29380215

Evaluation of the Diagnostic Performance of Fibrin Monomer in Comparison to d-Dimer in Patients With Overt and Nonovert Disseminated Intravascular Coagulation.

Singh N1, Pati HP1, Tyagi S1, Upadhyay AD2, Saxena R1.
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis.Clin Appl Thromb Hemost.2017 Jul;23(5):460-465. doi: 10.1177/1076029615615959. Epub 2015 Nov 15.
PMID 26574574

possible role of soluble fibrin monomer complex after gastroenterological surgery.

Kochi M1, Shimomura M1, Hinoi T1, Egi H1, Tanabe K1, Ishizaki Y1, Adachi T1, Tashiro H1, Ohdan H1.
World journal of gastroenterology.World J Gastroenterol.2017 Mar 28;23(12):2209-2216. doi: 10.3748/wjg.v23.i12.2209.
PMID 28405149

Japanese Journal

周術期の深部静脈血栓症におけるD-dimerと可溶性フィブリン測定の有用性の検討

島根医学検査 = The Shimane journal of medical technology : (一社)島根県臨床検査技師会会誌 45(1), 7-11, 2017-05
NAID 40021244829

D-dimerと可溶性フィブリンモノマー複合体の組合せによる腰椎疾患の周術期における静脈血栓塞栓症の検索方法 (日本脊椎・脊髄神経手術手技学会特集号)

Journal of spine research : official journal of the Japanese Society for Spine Surgery and Related Research 7(7), 1145-1149, 2016-07
NAID 40020922950

臨床経験肺血栓塞栓症・深部静脈血栓症急性期におけるフィブリン関連マーカー

麻酔 65(6), 578-582, 2016-06
NAID 40020870155

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