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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2017/03/04 00:31:19」(JST)

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Serostatus refers to the presence or absence of a serological marker in the blood. The presence of detectable levels of a specific marker within the serum is considered seropositivity, while the absence of such levels is considered seronegativity.

HIV/AIDS

The term serostatus is commonly used in HIV/AIDS prevention efforts. In recent years, social advocacy has emphasized the importance of learning one's HIV/AIDS serostatus in an effort to curtail the spread of the disease.^[1]

Autoimmune disease

Researchers have investigated the effects of autoantibody serostatus on autoimmune disease presentation.^[2]^[3]^[4] Study of seronegative patient populations has led to the identification of additional autoantibodies that could potentially help with diagnosis.^[5]^[6]

References

^ Janssen RS, Holtgrave DR, Valdiserri RO, et al. (July 2001). "The Serostatus Approach to Fighting the HIV Epidemic: prevention strategies for infected individuals". American Journal of Public Health. American Public Health Association. 91 (7): 1019–1024. doi:10.2105/AJPH.91.7.1019. ISSN 1541-0048. PMC 1446705. PMID 11441723.
^ Jarius S, Ruprecht K, Wildemann B, et al. (January 2012). "Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: A multicentre study of 175 patients". Journal of Neuroinflammation. BioMed Central. 9 (1): 14. doi:10.1186/1742-2094-9-14. PMC 3283476. PMID 22260418.
^ Ajeganova S, Huizinga TW (November 2014). "Rheumatoid arthritis: Seronegative and seropositive RA: alike but different?". Nature Reviews Rheumatology. Nature Publishing Group. 11 (1): 8–9. doi:10.1038/nrrheum.2014.194. ISSN 1759-4804. PMID 25403158.
^ Balasubramanian G, Sugumar A, Smyrk TC, et al. (2012). "Demystifying seronegative autoimmune pancreatitis". Pancreatology. Elsevier. 12 (4): 289–294. doi:10.1016/j.pan.2012.05.003. PMID 22898628.
^ Somers K, Geusens P, Elewaut D, et al. (February 2011). "Novel autoantibody markers for early and seronegative rheumatoid arthritis". Journal of Autoimmunity. Elsevier. 36 (1): 33–46. doi:10.1016/j.jaut.2010.10.003. ISSN 0896-8411. PMID 21071175.
^ Pevzner A, Schoser B, Peters K, et al. (August 2011). "Anti-LRP4 autoantibodies in AChR- and MuSK-antibody-negative myasthenia gravis" (PDF). Journal of Neurology. Springer-Verlag. 259 (3): 427–435. doi:10.1007/s00415-011-6194-7. ISSN 1432-1459. PMID 21814823.

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English Journal

Toxoplasma gondii exposure may modulate the influence of TLR2 genetic variation on bipolar disorder: a gene-environment interaction study.

Oliveira J1,2, Kazma R3, Le Floch E3, Bennabi M1,2, Hamdani N2,4,5,6, Bengoufa D7, Dahoun M7, Manier C1, Bellivier F8,9, Krishnamoorthy R1, Deleuze JF3, Yolken R10,11, Leboyer M2,4,5,6, Tamouza R12,13,14,15.
International journal of bipolar disorders.Int J Bipolar Disord.2016 Dec;4(1):11. doi: 10.1186/s40345-016-0052-6. Epub 2016 May 20.
BACKGROUND: Genetic vulnerability to environmental stressors is yet to be clarified in bipolar disorder (BD), a complex multisystem disorder in which immune dysfunction and infectious insults seem to play a major role in the pathophysiology. Association between pattern-recognition receptor coding ge
PMID 27207565

Spatial and temporal epidemiology of Mycobacterium leprae infection among leprosy patients and household contacts of an endemic region in Southeast Brazil.

Nicchio MV1, Araujo S2, Martins LC3, Pinheiro AV4, Pereira DC4, Borges A5, Antunes DE1, Barreto JG6, Goulart IM1.
Acta tropica.Acta Trop.2016 Nov;163:38-45. doi: 10.1016/j.actatropica.2016.07.019. Epub 2016 Jul 25.
BACKGROUND: Leprosy is a chronic infectious disease that remains a public health problem in low- and middle-income countries. Household contacts of leprosy patients (HHCs) have increased risk of developing disease and are important links in the chain of transmission of Mycobacterium leprae. Based on
PMID 27469619

The induction of autoimmune hepatitis in the human leucocyte antigen-DR4 non-obese diabetic mice autoimmune hepatitis mouse model.

Yuksel M1,2,3, Xiao X1,4, Tai N1, Vijay GM1,3, Gülden E1, Beland K5, Lapierre P6, Alvarez F5, Hu Z4, Colle I2, Ma Y3, Wen L7.
Clinical and experimental immunology.Clin Exp Immunol.2016 Nov;186(2):164-176. doi: 10.1111/cei.12843. Epub 2016 Aug 23.
Autoimmune hepatitis (AIH) is a chronic liver disease characterized by progressive inflammation, female preponderance and seropositivity for autoantibodies such as anti-smooth muscle actin and/or anti-nuclear, anti-liver kidney microsomal type 1 (anti-LKM1) and anti-liver cytosol type 1 (anti-LC1) i
PMID 27414259

Japanese Journal

Human Immunodeficiency Virus Seroprevalence among Patients Attending a Sexually Transmitted Disease Clinic in West Bengal, India

Maity Susmita,Nandi Srijita,Biswas Subrata,Saha Malay Kumar
Japanese Journal of Infectious Diseases 65(5), 424-426, 2012
… Overall HIV seropositivity in STD patients was 1.28% (women, 1.04%; …
NAID 130001931852

Post-Pandemic Seroprevalence of 2009 Pandemic Influenza A (H1N1) Virus in Shandong Province, China

Liu Ti,Li Zhong,Song Shaoxia,Zhang Shengyang,Wang Yulu,Lin Yi,Wang Shuang,Wang Xianjun,Xu Aiqiang,Bi Zhenqiang
Japanese Journal of Infectious Diseases 65(5), 410-414, 2012
… Multivariate logistic regression revealed that subjects in rural areas had significantly higher odds ratio of A(H1N1)pdm09 seropositivity than those in the capital city. … Individuals belonging to all professions, except for teachers, had significantly lower odds ratio of A(H1N1)pdm09 seropositivity compared with children in family care. …
NAID 130001931850

Epidemiology of Bovine Brucellosis by a Combination of Rose Bengal Test and Indirect ELISA in the Five Districts of Uganda

KASHIWAZAKI Yoshihito,ECEWU Ekisu,IMALIGAT Joseph O.,MAWEJJE Robert,KIRUNDA Moses,KATO Moses,MUSOKE Godfrey M.,ADEMUN Rose A. O.
Journal of Veterinary Medical Science 74(11), 1417-1422, 2012
… A similar trend was also observed in Kumi, namely, the seropositivity significantly increased from 2.3% in 2007 to 6.2% in 2008 and became remarkably higher than in Mbale (0.64%). …
NAID 130001879730