WordNet

a part of the cell containing DNA and RNA and responsible for growth and reproduction (同)cell_nucleus, karyon
(astronomy) the center of the head of a comet; consists of small solid particles of ice and frozen gas that vaporizes on approaching the sun to form the coma and tail
any histologically identifiable mass of neural cell bodies in the brain or spinal cord
the positively charged dense center of an atom
of or relating to a septum (同)septate

PrepTutorEJDIC

中心,核 / (生物の)細胞核 / 原子核

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/09/30 21:22:30」(JST)

wiki en

The septal nuclei (medial olfactory area) are a set of structures that lie below the rostrum of the corpus callosum, anterior to the lamina terminalis (the layer of gray matter in the brain connecting the optic chiasma and the anterior commissure where the latter becomes continuous with the rostral lamina). The septal nuclei are composed of medium-size neurons which are classified into medial, lateral, and posterior groups. The septal nuclei receive reciprocal connections from the olfactory bulb, hippocampus, amygdala, hypothalamus, midbrain, habenula, cingulate gyrus, and thalamus. The septal area (medial olfactory area) has no relation to the smell, but it is considered a pleasure zone in animals. The septal nuclei play a role in reward and reinforcement along with the nucleus accumbens. In the 1950s, Olds & Milner showed that rats with electrodes implanted in this area will self-stimulate repeatedly (i.e. press a bar to receive electrical current that will stimulate the neurons).^[1]

Connections with other structures[edit]

The dorsal septum projects to the lateral preoptic area, lateral hypothalamus, periventricular hypothalamus and midline thalamus.

Fibers from the ventral half of the septum project topographically to the hippocampal formation, thalamus, hypothalamus and midbrain. Specifically, neurons located along the midline in the vertical limb of the diagonal band of Broca project through the dorsal fornix to all CA fields of the dorsal hippocampus and adjacent subicular cortex. Other fibers from this region project through the stria medullaris to the medial and lateral habenular nuclei, the paratenial and anteromedial nucleus of the thalamus, and through the medial forebrain bundle to the pars posterior of the medial mammillary nucleus.

Cells located in the intermediolateral septum also project through the lateral part of the fimbria to all CA fields of the ventral hippocampus and adjacent subicular and entorhinal cortices. These cells also send fibers through the stria medullaris to the lateral habenular nucleus and mediodorsal thalamic nucleus. Other axons arising from these cells descend through the medial forebrain bundle to terminate in a region dorsal to the interpeduncular nucleus.

The lateral septum is a relay center for connections from the CA3 of the hippocampus to the ventral tegmental area. These connections help link reward signals with the context in which they occur.^[2]

Fibers from the most lateral part of the ventral septum (i.e., bed nucleus of the anterior commissure) project through the stria terminalis to the ventral subiculum. In addition, cells located in the horizontal limb of the diagonal band project massively to the pars posterior of the medial mammillary nucleus, the ventral tegmental area, and amygdala.

External links[edit]

BrainMaps at UCDavis septal%20nuclei

References[edit]

^ Olds, J; Milner, P (1954 Dec). "Positive reinforcement produced by electrical stimulation of septal area and other regions of rat brain.". Journal of comparative and physiological psychology 47 (6): 419–27. PMID 13233369. Retrieved 17 March 2013.
^ Luo, A. H.; Tahsili-Fahadan, P.; Wise, R. A.; Lupica, C. R.; Aston-Jones, G. (14 July 2011). "Linking Context with Reward: A Functional Circuit from Hippocampal CA3 to Ventral Tegmental Area". Science 333 (6040): 353–357. doi:10.1126/science.1204622. |accessdate= requires |url= (help)

Neuroanatomy book of mansoura faculty of medicine(Egypt)

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 成人における心房中隔欠損症のマネージメント management of atrial septal defects in adults
2. 小児における孤立性心房中隔欠損の臨床的特徴および分類 classification and clinical features of isolated atrial septal defects in children
3. 成人における心房中隔異常（PFO、ASD、およびASA）および脳塞栓症のリスク atrial septal abnormalities pfo asd and asa and risk of cerebral emboli in adults
4. 小児における孤立性心房中隔欠損のマネージメントおよび転帰 management and outcome of isolated atrial septal defects in children
5. 二次心房中隔欠損症の経皮閉鎖に用いるデバイス devices for percutaneous closure of a secundum atrial septal defect

English Journal

Alteration of the CNS pathway to the hippocampus in a mouse model of Niemann-Pick, type C disease.

Byun K, Kim JM, Kim N, Kang JA, Won MH, Jeong GB, Jo SM, Lee B.SourceCenter for Genomics and Proteomics, Lee Gil Ya Cancer and Diabetes Institute, Gachon University of Medicine and Science, Incheon 406-840, South Korea; Department of Anatomy and Cell Biology, Gachon University of Medicine and Science, Incheon 406-799, South Korea.
Journal of chemical neuroanatomy.J Chem Neuroanat.2011 Sep;42(1):39-44. Epub 2011 Apr 27.
Niemann-Pick type C disease (NPC) is an autosomal recessive disorder that results in premature death due to progressive neurodegeneration including dementia. To understand neuronal pathways connecting to the hippocampus, retrograde transneuronal labeling method with Bartha strain of pseudorabies vir
PMID 21549832

Experimental transmission of h-type bovine spongiform encephalopathy to bovinized transgenic mice.

Okada H, Masujin K, Iwamaru Y, Imamura M, Matsuura Y, Mohri S, Czub S, Yokoyama T.SourceDVM, PhD, Prion Disease Research Center, National Institute of Animal Health, 3-1-5 Kan-nondai, Tsukuba, Ibaraki 305-0856, Japan Email: okadahi@affrc.go.jp.
Veterinary pathology.Vet Pathol.2011 Sep;48(5):942-7. Epub 2010 Oct 4.
To characterize the biological and biochemical properties of H-type bovine spongiform encephalopathy (BSE), a transmission study with a Canadian H-type isolate was performed with bovinized transgenic mice (TgBoPrP), which were inoculated intracerebrally with brain homogenate from cattle with H-type
PMID 20921323

Japanese Journal

Effects of Tandospirone, a 5-HT_<1A> Agonistic Anxiolytic Agent, on Haloperidol-Induced Catalepsy and Forebrain Fos Expression in Mice

OHNO Yukihiro,SHIMIZU Saki,IMAKI Junta
Journal of pharmacological sciences 109(4), 593-599, 2009-04-20
… Haloperidol (0.5 mg/kg, i.p.) markedly increased the catalepsy time and enhanced Fos expression in the shell (AcS) and core (AcC) regions of the nucleus accumbens, the dorsolateral striatum (dlST), and the lateral septal nucleus (LSN). …
NAID 10025736020