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1. そう痒症：疫学および患者評価pruritus etiology and patient evaluation [show details]
…related to xerosis is characterized by itching in areas of dry, scaly skin Xerosis is a common cause of pruritus in older adults . Symptoms often occur on the lower extremities. Severe xerosis may also… chronic venous insufficiency. Idiopathic itch in older adults, sometimes inappropriately referred to as senile pruritus, presents a diagnostic and therapeutic challenge . Age-related changes in nerve fibers and …
2. そう痒症：マネージメントの概要pruritus overview of management [show details]
…disorders that present with pruritus are discussed separately . Xerosis and lichen simplex chronicus are briefly discussed below. Xerosis is common in older adults and in people living in northern climates …
3. アミロイドーシスの概要overview of amyloidosis [show details]
…in myocardium and other sites may result in a form of amyloidosis that is referred to as systemic senile amyloidosis (SSA) . Some experts prefer to reserve use of the term SSA for those patients who develop …
4. 舞踏病の概要overview of chorea [show details]
…disorders; infectious diseases; toxins; drugs ; structural lesions of the basal ganglia; and so-called senile chorea. Chorea can occur as a consequence of acute ischemic or hemorrhagic stroke or in the context …
5. シェーグレン症候群の臨床症状：腺外型疾患clinical manifestations of sjogrens syndrome extraglandular disease [show details]
…positive anti-Ro/SSA serology or a positive lip biopsy . The major skin findings in SS include : Xerosis (ie, abnormal dryness) Purpura, associated with vascular or hematologic abnormalities Raynaud …

English Journal

The 24-hr, 28-day, and 7-day post-moisturizing efficacy of ceramides 1, 3, 6-II containing moisturizing cream compared with hydrophilic cream on skin dryness and barrier disruption in senile xerosis treatment.

Lueangarun S, Tragulplaingam P, Sugkraroek S, Tempark T.
Dermatologic therapy. 2019 11;32(6)e13090.
Direct replacement of decreased ceramides in the stratum corneum can be efficacious for skin hydration, skin barrier function, and skin pH. Our study aimed to evaluate the 24-hr, 28-day, and 7-day post-moisturizing efficacy of ceramide-containing moisturizer in senile xerosis treatment. A split site
PMID 31585489

Presence and characteristics of among Danish elderly living in nursing homes.

Dyhre-Petersen N, Gazerani P.
Future science OA. 2019 Jun;5(6)FSO399.
To explore the pattern of occurrence and characteristics of among elderly living in nursing homes in the Northern region of Denmark. A Danish questionnaire was developed and distributed to six nursing homes from which 46 residents participated. The prevalence of chronic itch was 28.9%. Evening-nigh
PMID 31285844

Efficacy of an emollient containing diethylene glycol/dilinoleic acid copolymer for the treatment of dry skin and pruritus in patients with senile xerosis.

Izumi R, Negi O, Suzuki T, Tominaga M, Kamo A, Suga Y, Matsukuma S, Takamori K.
Journal of cosmetic dermatology. 2017 Dec;16(4)e37-e41.
Pruritus frequently reduces quality of life (QOL) in patients with senile xerosis. This study investigated the moisturizing and antipruritic effects of a topical emollient containing a diethylene glycol/dilinoleic acid copolymer (D/DC) in patients with pruritic senile xerosis. This single-blind stud
PMID 28371078

Japanese Journal

加齢に伴う皮膚の老化メカニズム (特集皮膚老化メカニズムの最先端研究と化粧品開発)

鎌田弥生,冨永光俊,古宮栄利子,髙森建二
Cosmetic stage 13(6), 16-20, 2019-08
NAID 40022008032

皮脂欠乏症（乾皮症）について―皮脂欠乏症の定義とその治療課題―

菊地克子,五十嵐敦之,加藤則人,生駒晃彦,金久保暁,照井正
日本皮膚科学会雑誌 129(13), 2763-2770, 2019
皮脂欠乏症は乾皮症と同義であり，加齢により生じる老人性乾皮症や皮膚機能が未成熟である乳幼児に生じるもののほか，アトピー性皮膚炎や魚鱗癬あるいは糖尿病や慢性腎臓病などの疾患に併発すると共に，一部の抗がん剤や放射線治療などに伴っても生じる．皮膚乾燥はしばしば瘙痒を伴い，搔破によって湿疹などの状態になることから，セルフメディケーション製品を含めた保湿剤による治療を疾患や病態に合わせて行 …
NAID 130007769944

高齢者の乾皮症に対する化粧品保湿クリームの検討

越智沙織,髙橋彩,片山一朗
皮膚の科学 17(5), 274-283, 2018
高齢者の乾皮症に対する化粧品保湿剤の影響を解析した。2017年 2 月から 4 月の間，大阪大学医学部附属病院を受診した60歳以上の乾皮症患者30例を対象とし，常盤薬品工業株式会社が販売してい …
NAID 130007628047