WordNet

inflammation of the tonsils (especially the palatine tonsils)

PrepTutorEJDIC

再発する;繰り返し起こる
扁桃腺炎

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1. 成人における扁桃摘出：適応 tonsillectomy in adults indications
2. 小児における扁桃摘出およびアデノイド切除：適応および禁忌 tonsillectomy and adenoidectomy in children indications and contraindications
3. 感染症を繰り返す小児に対するアプローチ approach to the child with recurrent infections
4. 成人における扁桃摘出：外科手技 tonsillectomy in adults operative procedures
5. マンノース結合レクチン欠損症 mannose binding lectin deficiency

English Journal

Tonsillotomy: facts and fiction.

Windfuhr JP1, Savva K, Dahm JD, Werner JA.Author information 1Department of Otorhinolaryngology, Plastic Head and Neck Surgery, Kliniken Maria Hilf Mönchengladbach, Sandradstr. 43, 41061, Mönchengladbach, Germany, jochen.windfuhr@mariahilf.de.AbstractIn contrast to total or extracapsular tonsillectomy (TE), subtotal/intracapsular/partial tonsillectomy (SIPT) or tonsillotomy (TT) is associated with significant less postoperative morbidity. It has been stated that patients older than 8 years of age or with a history of tonsillitis should be excluded from SIPT/TT. Some health insurance companies mandate utilization of particular surgical instruments. Finally, it has been stated that the remaining tonsillar tissue may become a subject of recurrent tonsillitis or tonsillar regrowth, in both cases requiring revision surgery in terms of TE. This literature review was undertaken to clarify what has been validated in the literature concerning indications, surgical techniques, complications and outcome of SIPT/TT as reported since 1960. A Medline review was undertaken and all papers included that were published in English or German language until September 30, 2013. Exclusion criteria were: publication date 1960 and earlier, other languages, no relation to tonsil surgery, papers not available to the authors, uncommon surgical techniques, national surveys or studies without patients. The quality of the papers was classified according to "The Oxford 2011 Levels of Evidence". The surgical techniques were classified according to Windfuhr and Werner and extended to interstitial tonsil therapy. Other issues were: study period, hemorrhage, dehydration, intake of analgesics, return to normal diet, surgical instruments, operation time, number of surgeons involved, number of patients, age, indications, follow-up, rate of tonsillar regrowth, tonsillitis and secondary TE. A total of 379 different publications were retrieved, but only 86 studies found eligible for further analysis. There were 10,499 patients in the study groups and 10,448 patients in the control groups. Utilization of the microdebrider largely prevailed, followed by Coblation, CO2-LASER, surgical scissor, Radiofrequency, Interstitial ThermoTherapy with various instruments, Diode-LASER, and other instruments. Instruments were not specified for 1,815 patients. Data for operation time, intraoperative bleeding, return to normal diet, analgesic intake were in favor for SIPT/TT and ablation procedures. Regrowth and tonsillitis occurred in rates of <6 % on average. Secondary surgery became necessary in only every third patient of this subgroup. Studies of variable quality impede comparison of all aspects in the papers. At least every second study did not address issues like operation time, intraoperative bleeding, return to normal diet, analgesic intake, rates of tonsillar regrowth, postsurgical tonsillitis and secondary TE. There are insufficient data to show that a single surgical instrument is superior. A history of tonsillitis and an age >8 years are definitely not commonly accepted as contraindication for SIPT, TT or ablation procedures. There is a strong evidence that pain is less after SIPT, TT and tonsil ablation resulting in an earlier return to normal diet and activity. Large, well-designed randomized controlled trials with an adequate follow-up are necessary to determine whether the procedure is capable to replace TE to resolve upper airway obstruction resulting from tonsillar hypertrophy as well as recurrent episodes of tonsillitis in children and adults.
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery.Eur Arch Otorhinolaryngol.2014 Apr 3. [Epub ahead of print]
In contrast to total or extracapsular tonsillectomy (TE), subtotal/intracapsular/partial tonsillectomy (SIPT) or tonsillotomy (TT) is associated with significant less postoperative morbidity. It has been stated that patients older than 8 years of age or with a history of tonsillitis should be exclu
PMID 24695941

Cost Analysis of Tonsillectomy in Children Using Medicaid Data.

Chang JJ1, Buchanan P2, Geremakis C2, Sheikh K3, Mitchell RB4.Author information 1Department of Epidemiology, College for Public Health and Social Justice, Saint Louis University, St. Louis, MO. Electronic address: jjchang@slu.edu.2Center for Outcome Research, Saint Louis University, St. Louis, MO.3Department of Health Policy and Management, University of Kansas Medical School, Kansas City, KS.4Southwestern and Children's Medical Center Dallas, University of Texas, Dallas, TX.AbstractOBJECTIVE: To evaluate the cost-effectiveness of adenotonsillectomy (T&A) for adenotonsillar hypertrophy and recurrent tonsillitis through the use of Missouri Medicaid data.
The Journal of pediatrics.J Pediatr.2014 Mar 14. pii: S0022-3476(14)00083-3. doi: 10.1016/j.jpeds.2014.01.055. [Epub ahead of print]
OBJECTIVE: To evaluate the cost-effectiveness of adenotonsillectomy (T&A) for adenotonsillar hypertrophy and recurrent tonsillitis through the use of Missouri Medicaid data.STUDY DESIGN: Children ages 2-16 years who had a diagnosis of adenotonsillar hypertrophy (based on medical claim codes) in
PMID 24631119

International periodic fever, aphthous stomatitis, pharyngitis, cervical adenitis syndrome cohort: description of distinct phenotypes in 301 patients.

Hofer M1, Pillet P, Cochard MM, Berg S, Krol P, Kone-Paut I, Rigante D, Hentgen V, Anton J, Brik R, Neven B, Touitou I, Kaiser D, Duquesne A, Wouters C, Gattorno M.Author information 1Paediatric Rheumatology Unit of Western Switzerland, Department of Paediatrics, CHUV, University Hospital of Lausanne, Lausanne, Department of Paediatrics, HUG, Geneva, Switzerland, Paediatric Rheumatology, Department of Paediatrics, Hôpital Pellegrin, Bordeaux, France, Paediatric Rheumatology, University of Gothenburg, Gothenburg, Sweden, Paediatric Rheumatology, Department of Paediatrics and Adolescent Medicine, Charles University, Prague, Czech Republic, Paediatric Rheumatology, Department of Paediatrics, CEREMAI, CHU de Bicêtre, APHP, Paris SUD, Faculty of Medicine, Le Kremlin-Bicêtre, France, Paediatric Rheumatology, Department of Paediatric Sciences, Università Cattolica Sacro Cuore, Rome, Italy, CEREMAI (National Centre for Auto-Inflammatory Diseases), Department of Paediatrics, Hôpital Mignot, Versailles, France, Paediatric Rheumatology, Department of Paediatrics, Hospital Sant Joan de Déu, Universitat de Barcelona, Barcelona, Spain, Paediatric Rheumatology, Meyer Children's Hospital of Haifa Rambam Medical Center, Faculty of Medicine, Technion Haifa, Israel, Paediatric Rheumatology, Hôpital Necker-Enfants Malades, Paris, France, Unité Médicale des Maladies Auto-Inflammatoires, Hôpital A de Villeneuve, Montpellier, France, Paediatric Rheumatology, Kantonspital, Lucerne, Switzerland, Paediatric Rheumatology, Hôpital Femme-Mère-Enfant, Lyon, France, Paediatric Rheumatology, Department of Paediatrics, University Hospital Leuven, Leuven, Belgium and UO Pediatria 2, Rheumatology Unit, G. Gaslini Institute, Genoa, Italy.AbstractObjectives. The aims of this study were to describe the clinical features of periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis (PFAPA) and identify distinct phenotypes in a large cohort of patients from different countries.Methods. We established a web-based multicentre cohort through an international collaboration within the periodic fevers working party of the Pediatric Rheumatology European Society (PReS). The inclusion criterion was a diagnosis of PFAPA given by an experienced paediatric rheumatologist participating in an international working group on periodic fever syndromes.Results. Of the 301 patients included from the 15 centres, 271 had pharyngitis, 236 cervical adenitis, 171 oral aphthosis and 132 with all three clinical features. A total of 228 patients presented with additional symptoms (131 gastrointestinal symptoms, 86 arthralgias and/or myalgias, 36 skin rashes, 8 neurological symptoms). Thirty-one patients had disease onset after 5 years and they reported more additional symptoms. A positive family history for recurrent fever or recurrent tonsillitis was found in 81 patients (26.9%). Genetic testing for monogenic periodic fever syndromes was performed on 111 patients, who reported fewer occurrences of oral aphthosis or additional symptoms. Twenty-four patients reported symptoms (oral aphthosis and malaise) outside the flares. The CRP was >50 mg/l in the majority (131/190) of the patients tested during the fever.Conclusion. We describe the largest cohort of PFAPA patients presented so far. We confirm that PFAPA may present with varied clinical manifestations and we show the limitations of the commonly used diagnostic criteria. Based on detailed analysis of this cohort, a consensus definition of PFAPA with better-defined criteria should be proposed.
Rheumatology (Oxford, England).Rheumatology (Oxford).2014 Mar 6. [Epub ahead of print]
Objectives. The aims of this study were to describe the clinical features of periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis (PFAPA) and identify distinct phenotypes in a large cohort of patients from different countries.Methods. We established a web-based multicentre cohort t
PMID 24505122

Japanese Journal

Immunization with heat-inactivated Staphylococcus aureus induced an antibody response mediated by IgG1 and IgG2 in patients with recurrent tonsillitis

Microbiology and immunology 59(4), 193-201, 2015-04
NAID 40020440529

Application of an enzyme-labeled antigen method for visualizing plasma cells producing antibodies against Strep A, a carbohydrate antigen of Streptococcus pyogenes, in recurrent tonsillitis