ramatroban

ラマトロバン


Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/10/16 21:48:28」(JST)

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English Journal

  • Central CRTH2, a second prostaglandin D2 receptor, mediates emotional impairment in the lipopolysaccharide and tumor-induced sickness behavior model.
  • Haba R1, Shintani N, Onaka Y, Kanoh T, Wang H, Takenaga R, Hayata A, Hirai H, Nagata KY, Nakamura M, Kasai A, Hashimoto R, Nagayasu K, Nakazawa T, Hashimoto H, Baba A.
  • The Journal of neuroscience : the official journal of the Society for Neuroscience.J Neurosci.2014 Feb 12;34(7):2514-23. doi: 10.1523/JNEUROSCI.1407-13.2014.
  • Chemoattractant receptor-homologous molecule expressed on T helper type 2 cells (CRTH2) is a second prostaglandin D2 receptor involved in mediating the allergic response; however, its central function is not yet known. Here, we demonstrate that central CRTH2 mediates emotional impairment. Lipopolysa
  • PMID 24523542
  • Inverse agonism of SQ 29,548 and Ramatroban on Thromboxane A2 receptor.
  • Chakraborty R1, Bhullar RP2, Dakshinamurti S3, Hwa J4, Chelikani P5.
  • PloS one.PLoS One.2014 Jan 23;9(1):e85937. doi: 10.1371/journal.pone.0085937. eCollection 2014.
  • G protein-coupled receptors (GPCRs) show some level of basal activity even in the absence of an agonist, a phenomenon referred to as constitutive activity. Such constitutive activity in GPCRs is known to have important pathophysiological roles in human disease. The thromboxane A2 receptor (TP) is a
  • PMID 24465800
  • Inhibition of antigen-induced airway inflammation and hyperresponsiveness in guinea pigs by a selective antagonist of "chemoattractant receptor homologous molecule expressed on Th2 cells" (CRTH2).
  • Tasaki M1, Kobayashi M, Tenda Y, Tsujimoto S, Nakazato S, Numazaki M, Hirano Y, Matsuda H, Terasaka T, Miyao Y, Shimizu Y, Hirayama Y.
  • European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.Eur J Pharm Sci.2013 Jun 14;49(3):434-40. doi: 10.1016/j.ejps.2013.04.017. Epub 2013 Apr 24.
  • Chemoattractant receptor homologous molecule expressed on T helper type 2 cells (CRTH2) is a PGD2 receptor found on eosinophils, basophils, and Th2 type T cells which exhibits chemotaxis and functions in activation cascades. However, while a number of CRTH2 antagonists, including ramatroban, are kno
  • PMID 23624353

Japanese Journal

  • Prophylactic Effects of the Histamine H1 Receptor Antagonist Epinastine and the Dual Thromboxane A2 Receptor and Chemoattractant Receptor-Homologous Molecule Expressed on Th2 Cells Antagonist Ramatroban on Allergic Rhinitis Model in Mice
  • ラマトロバンと抗ヒスタミン薬の併用による初期療法と飛散後治療の比較
  • スギ花粉症患者に対するラマトロバンの安全性

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Related Pictures

RamatrobanAcetylsalicylic acid is a covalent Ramatroban structure.pngRamatroban structure.pngRamatroban Cas 116649-85-5英文名称:Ramatroban



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