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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/04/07 10:55:19」(JST)

English Journal

2-Thiouracil deprived of thiocarbonyl function preferentially base pairs with guanine rather than adenine in RNA and DNA duplexes.

Sochacka E1, Szczepanowski RH2, Cypryk M3, Sobczak M3, Janicka M3, Kraszewska K3, Bartos P1, Chwialkowska A3, Nawrot B4.
Nucleic acids research.Nucleic Acids Res.2015 Mar 11;43(5):2499-512. doi: 10.1093/nar/gkv109. Epub 2015 Feb 17.
2-Thiouracil-containing nucleosides are essential modified units of natural and synthetic nucleic acids. In particular, the 5-substituted-2-thiouridines (S2Us) present in tRNA play an important role in tuning the translation process through codon-anticodon interactions. The enhanced thermodynamic st
PMID 25690900

Photochemistry. Chemiexcitation of melanin derivatives induces DNA photoproducts long after UV exposure.

Premi S1, Wallisch S1, Mano CM2, Weiner AB1, Bacchiocchi A3, Wakamatsu K4, Bechara EJ5, Halaban R6, Douki T7, Brash DE8.
Science (New York, N.Y.).Science.2015 Feb 20;347(6224):842-7. doi: 10.1126/science.1256022.
Mutations in sunlight-induced melanoma arise from cyclobutane pyrimidine dimers (CPDs), DNA photoproducts that are typically created picoseconds after an ultraviolet (UV) photon is absorbed at thymine or cytosine. We found that in melanocytes, CPDs are generated for >3 hours after exposure to UVA
PMID 25700512

Kupferschmidt K, Cohen J.
Science (New York, N.Y.).Science.2015 Feb 13;347(6223):701-2. doi: 10.1126/science.347.6223.701.
PMID 25678637

SYNTHESES OF 5-AMINO-2-PHENYL-4(3H)-PYRIMIDINONE DERIVATIVES STARTING WITH GLYCINE

Novel Pyrimidinone Derivatives: Synthesis, Antitumor and Antimicrobial Evaluation

Taher Azza Taher,Helwa Amira Atef
Chemical and Pharmaceutical Bulletin 60(4), 521-530, 2012
Starting from 6-aryl-4-oxo-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile (4a–d), a series of mono- and dialkyl derivatives 5a–j and 6a, b was synthesized. Hydrazinolysis of 4a, b, d and 5d affo …
NAID 130001852444

A facile synthesis of 2-substituted 2,3-dihydro-4(1H)-azuleno〔1,2-d〕pyrimidinones

4-Pyrimidone
	IUPAC name Pyrimidone
	Other names Hydroxypyrimidine; Pyrimidinone
Identifiers
CAS number	51953-17-4
PubChem	20695
Jmol-3D images	Image 1
	SMILES O=C1NC=NC=C1 ;
Properties
Molecular formula	C4H4N2O
Molar mass	96.09 g mol−1
Appearance	White to light yellow powder
Melting point	163-168 °C
Hazards
Main hazards	Respiratory system, eye, skin irritation
	Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
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	Infobox references