肺血管リモデリング
WordNet
- of or relating to or having vessels that conduct and circulate fluids; "vascular constriction"; "a vascular bundle"
PrepTutorEJDIC
- (血液・樹液などを運ぶ)管の,導管の,血管の
- 肺の;肺を冒す
UpToDate Contents
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- 1. 成人における肺高血圧症の概要 overview of pulmonary hypertension in adults
- 2. 肺高血圧症の病因 pathogenesis of pulmonary hypertension
- 3. 慢性血栓塞栓性肺高血圧症:内科的治療 chronic thromboembolic pulmonary hypertension medical treatment
- 4. 慢性血栓塞栓性肺高血圧症の治療の概要 overview of the treatment of chronic thromboembolic pulmonary hypertension
- 5. 新生児の持続性肺高血圧症 persistent pulmonary hypertension of the newborn
English Journal
- Novel therapeutic approaches for pulmonary arterial hypertension: Unique molecular targets to site-specific drug delivery.
- Vaidya B1, Gupta V2.
- Journal of controlled release : official journal of the Controlled Release Society.J Control Release.2015 Aug 10;211:118-33. doi: 10.1016/j.jconrel.2015.05.287. Epub 2015 May 31.
- Pulmonary arterial hypertension (PAH) is a cardiopulmonary disorder characterized by increased blood pressure in the small arterioles supplying blood to lungs for oxygenation. Advances in understanding of molecular and cellular biology techniques have led to the findings that PAH is indeed a cascade
- PMID 26036906
- Stepwise high-throughput virtual screening of Rho kinase inhibitors from natural product library and potential therapeutics for pulmonary hypertension.
- Su H1, Yan J, Xu J, Fan XZ, Sun XL, Chen KY.
- Pharmaceutical biology.Pharm Biol.2015 Aug;53(8):1201-6. doi: 10.3109/13880209.2014.970287. Epub 2015 Apr 8.
- CONTEXT: Pulmonary hypertension (PH) is a devastating disease characterized by progressive elevation of pulmonary arterial pressure and vascular resistance due to pulmonary vasoconstriction and vessel remodeling. The activation of RhoA/Rho-kinase (ROCK) pathway plays a central role in the pathologic
- PMID 25853972
- The Therapeutic Effects of Human Mesenchymal Stem Cells Primed with Sphingosine-1 Phosphate on Pulmonary Artery Hypertension.
- Kang H1,2, Kim KH3, Lim J1,2, Kim YS3, Heo J1,2, Choi J3, Jeong J1,2, Kim Y1,2, Kim SW4, Oh YM3, Choo MS5, Son J1, Kim SJ6, Yoo HJ6, Oh W7, Choi SJ7, Lee SW3, Shin DM1,2.
- Stem cells and development.Stem Cells Dev.2015 Jul 15;24(14):1658-71. doi: 10.1089/scd.2014.0496. Epub 2015 Apr 9.
- Stem cell (SC) therapy has become a potential treatment modality for pulmonary artery hypertension (PAH), but the efficacy of human SC and priming effects have not yet been established. The mobilization and homing of hematopoietic stem cells (HSCs) are modulated by priming factors that include a bio
- PMID 25761906
Japanese Journal
- 東邦医学会賞受賞記念講演要旨 平成25年度 ヒト終末期特発性肺動脈性肺高血圧症と比較した肺血管改築誘発マウスモデルに関する遺伝子発現変動解析
- 下平 佳代子
- 東邦医学会雑誌 = Journal of Medical Society of Toho University 61(1), 34-37, 2014-01
- 東邦医学会賞受賞記念講演要旨
- NAID 120005387693
- Rapamycin Attenuates Pulmonary Allergic Vasculitis in Murine Model by Reducing TGF-β Production in the Lung
- Koizumi Rumi,Sasaki Nobuhito,Nakamura Yutaka,Suzuki Naomi,Sawai Takashi,Yamauchi Kohei
- Allergology International 63(3), 457-466, 2014
- … Background: Rapamycin has been reported to inhibit mesenchymal cell proliferation in a murine model of pulmonary fibrosis. … In the present study, we examined the effects of rapamycin on vascular remodeling including intraluminal myofibroblast proliferation in a murine model of allergic vasculitis with eosinophil infiltration. … Semi-quantitative analysis of pathological changes in the pulmonary arteries was evaluated according to the severity of vasculitis. …
- NAID 130004687704
- Monocrotaline誘発肺高血圧ラットにおける肺小動脈リモデリング形成過程におけるMineralocorticoid receptor 拮抗剤eplerenoneの効果
- 羽森 貫,根本 慎太郎,佐々木 智康,勝間田 敬弘,岸 勘太,奥村 謙一,尾崎 智康,片山 博視
- Pediatric Cardiology and Cardiac Surgery 30(4), 438-447, 2014
- 肺高血圧症の病態の本質は肺動脈リモデリングである.しかし,肺高血圧症におけるaldosterone系のリモデリングへの関与は明らかでない.本研究ではmonocrotaline誘発肺高血圧ラットを用い,肺動脈リモデリングにおけるaldosterone系の関与を検討した.加えてmonocrotaline投与の翌日からの選択的mineralocorticoid receptor拮抗薬(eplerenon …
- NAID 130004684473
Related Links
- Pulmonary vascular remodelling is an important pathological feature of pulmonary hypertension, leading to increased pulmonary vascular resistance and reduced compliance. It involves thickening of all three layers of the blood vessel wall (due to hypertrophy and/or hyperplasia of the predominant cell type within each layer), as well as extracellular ...
- Over the next 1 to 2 months, the smaller arteries and arterioles of the lungs undergo normal, physiologic remodeling that results in a gradual decrease in pulmonary vascular resistance. The ability of the pulmonary vasculature to exercise these changes depends, in large part, on proper development.
- Pulmonary vascular remodeling is the key structural alteration in pulmonary hypertension and involves changes in the intima, media and adventitia, often with the interplay of inflammatory cells. This review examines the pathology of these changes and highlights some of the pathogenetic mechanisms th …. Pulmonary vascular remodeling is the key ...
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★リンクテーブル★
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- 英
- pulmonary vascular remodeling
- 関
- 肺血管
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- 関
- angio、blood vessel、fibrovascular bundle、vascular bundle、vasculogenic、vein、vessel
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- 関
- lung、pneumo