関: pulmonary plasma cell granuloma

WordNet

characterized or caused by inflammation; "an inflammatory process"; "an inflammatory response"

PrepTutorEJDIC

炎症を起こす,炎症性の / 憤激させる,扇動的な
肺の;肺を冒す

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1. 炎症性腸疾患の肺合併症 pulmonary complications of inflammatory bowel disease
2. 多発血管炎を伴う肉芽腫症（ウェゲナー）における気道病変 respiratory tract involvement in granulomatosis with polyangiitis wegeners
3. 肺の炎症性筋線維芽細胞性腫瘍（形質細胞肉芽腫） inflammatory myofibroblastic tumor plasma cell granuloma of the lung
4. 小児における末梢のリンパ節腫脹の原因 causes of peripheral lymphadenopathy in children
5. 限局性肝病変を有する患者に対するアプローチ approach to the patient with a focal liver lesion

English Journal

Pulmonary inflammatory myofibroblastic tumor and IgG4-related inflammatory pseudotumor: a diagnostic dilemma.

Bhagat P1, Bal A, Das A, Singh N, Singh H.Author information 1Department of Histopathology, Post Graduate Institute of Medical Sciences & Research (PGIMER), Sector - 12, Chandigarh, 160012, India.AbstractIgG4-related inflammatory pseudotumor (IPT) and inflammatory myofibroblastic tumor (IMT) share morphological features like a prominent fibroblastic/myofibroblastic proliferation and the presence of inflammatory cells. Since IPT is managed conservatively and IMT is treated by surgical excision, it is important to differentiate these two lesions. The aim of this study is to highlight morphological and immunohistochemical features that distinguish IPT and IMT. Clinicopathological characteristics of cases diagnosed as pulmonary IPT or IMT from 1997 to 2013 were reviewed. The histological features were studied on hematoxylin and eosin-stained sections. Immunohistochemistry was done for IgG, IgG4, ALK-1, SMA, desmin, and CD34 for classification into IPT and IMT. Of the ten patients, seven were male and the age ranged from 4 to 58 years. The tumor size ranged from 1.5 to 4.0 cm in diameter. Histologically, proliferation of bland-looking spindle cells along with fibrosis and an inflammatory infiltrate comprising of lymphocytes and plasma cells were the common morphological features of both lesions. The spindle cell proliferation was more marked in IMT whereas lymphoplasmacytic infiltrate was more prominent in IPT. Obstructive phlebitis was observed only in cases of IPT. IgG4 expression was noted in IPT, and the number of IgG4-positive plasma cells and the ratio of IgG4+/IgG+ plasma cells were significantly lower in IMT than in IgG4-related IPT. Expression of anaplastic lymphoma kinase (ALK) was observed only in IMT, but not in IgG4-related IPT. The proportion of proliferating spindle cells, lymphoplasmacytic infiltrate, obstructive phlebitis, IgG4+ plasma cells and the ratio of IgG4+/IgG+ plasma cells, and ALK expression are helpful in differentiating these morphologically similar but biologically different lesions, which require different treatment modalities.
Virchows Archiv : an international journal of pathology.Virchows Arch.2013 Dec;463(6):743-7. doi: 10.1007/s00428-013-1493-2. Epub 2013 Oct 8.
IgG4-related inflammatory pseudotumor (IPT) and inflammatory myofibroblastic tumor (IMT) share morphological features like a prominent fibroblastic/myofibroblastic proliferation and the presence of inflammatory cells. Since IPT is managed conservatively and IMT is treated by surgical excision, it is
PMID 24100523

Postradiofrequency ablation inflammatory pseudotumor associated with pulmonary venoocclusive disease: case report and review of the literature.

Kovach AE1, Cheng GZ, Channick CL, Channick RN, Muniappan A, Gaissert HA, Kradin RL.Author information 1Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA.AbstractRadiofrequency ablation of pulmonary veins is a common therapeutic intervention for atrial fibrillation. Pulmonary vein stenosis and venoocclusive disease are recognized complications, but the spectrum of pathologies postablation have not been previously reviewed. A recent case at our hospital showed a left hilar soft tissue mass in association with superior pulmonary vein stenosis in a patient 4 years postablation. On resection, this proved to be an inflammatory pseudotumor composed of myofibroblasts in an organizing pneumonia-type pattern with adjacent dendriform ossifications. Pulmonary venoocclusive change was a prominent feature. Literature on the histopathology of postradiofrequency ablation complications is limited. The severity of vascular pathology appears to increase with the postablation interval. Although pulmonary vascular changes are the most common late finding, fibroinflammatory changes including pulmonary pseudotumor formation, attributable to thermal injury, should be considered in the differential diagnosis of these cases.
Annals of diagnostic pathology.Ann Diagn Pathol.2013 Oct;17(5):466-9. doi: 10.1016/j.anndiagpath.2012.11.002. Epub 2013 Jan 22.
Radiofrequency ablation of pulmonary veins is a common therapeutic intervention for atrial fibrillation. Pulmonary vein stenosis and venoocclusive disease are recognized complications, but the spectrum of pathologies postablation have not been previously reviewed. A recent case at our hospital showe
PMID 23352326

Huge inflammatory myofibroblastic tumor of pleura with concomitant nuchal fibroma.

Döngel I1, Yazkan R, Duman L, Oztürk O, Kapucuoğlu FN.Author information 1Department of Thoracic Surgery, Süleyman Demirel University, Medical Faculty, Isparta, Turkey. Electronic address: drdongel@hotmail.com.AbstractInflammatory myofibroblastic tumor (IMT) is a rare benign neoplasm. It is a challenging disease because the symptoms and radiologic findings are diverse and nonspecific. Although pulmonary IMT is the most common form, pleural origin is an extremely rare clinical entity. Nuchal fibroma (NF) is another rare benign neoplasm. We report herein a case of pleural IMT with concomitant NF in a 15-year-old girl. To the best of our knowledge, this is the first report suggesting an association between IMT and NF, and our case had the largest reported intrathoracic IMT. Moreover, we found a possible association between IMT and increased CA-125 levels.
The Annals of thoracic surgery.Ann Thorac Surg.2013 Oct;96(4):1461-4. doi: 10.1016/j.athoracsur.2013.01.082.
Inflammatory myofibroblastic tumor (IMT) is a rare benign neoplasm. It is a challenging disease because the symptoms and radiologic findings are diverse and nonspecific. Although pulmonary IMT is the most common form, pleural origin is an extremely rare clinical entity. Nuchal fibroma (NF) is anothe
PMID 24088461

Japanese Journal

高IgG血症, 自己免疫性膵炎の経過中に認められた肺炎症性偽腫瘍の1例

田村真理子,竹山佳宏,山本雅史,島浩一郎,鈴木勝雄,中村俊信,浅野俊明,吉田健也
日本呼吸器学会雑誌 = The journal of the Japanese Respiratory Society 46(11), 909-914, 2008-11-10
NAID 10024822772

Inflammatory Pseudotumors in Multiple Organs Associated with Elevated Serum IgG4 Level: Recovery by Only a Small Replacement Dose of Steroid

Tsuboi Hiroto,Inokuma Shigeko,Setoguchi Keigo,Shuji Sumitomo,Hagino Noboru,Tanaka Yoshiaki,Yoshida Nozomi,Hishima Tsunekazu,Kamisawa Terumi
Internal Medicine 47(12), 1139-1142, 2008
… Images showed swelling of pituitary stalk, mediastinal and hilar lymphnodes and pancreas, pulmonary infiltrates and retroperitoneal mass. … Lung biopsy revealed pseudotumor containing IgG4-positive plasmacytes, and obliterative vasculitis both in arterioles and venules. …
NAID 130000078865