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a disorder characterized by deposit of amyloid in organs or tissues; often secondary to chronic rheumatoid arthritis or tuberculosis or multiple myeloma

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1. アミロイドーシスの概要 an overview of amyloidosis
2. 間質性肺疾患における肺生検結果の解釈 interpretation of lung biopsy results in interstitial lung disease
3. シェーグレン症候群関連間質性肺疾患：臨床症状、評価、および診断 interstitial lung disease associated with sjogrens syndrome clinical manifestations evaluation and diagnosis
4. シェーグレン症候群関連間質性肺疾患：管理と予後 interstitial lung disease associated with sjogrens syndrome management and prognosis

Use of argatroban and catheter-directed thrombolysis with alteplase in an oncology patient with heparin-induced thrombocytopenia with thrombosis.

Dee B1, Thomas LL, Gulbis A.Author information 1Brian Dee, Pharm.D., BCPS, BCNSP, is Clinical Pharmacy Specialist-Critical Care/Nutrition Support; Lindsey Lombardi Thomas, Pharm.D., BCOP, is Clinical Pharmacy Specialist-Stem Cell Transplantation; and Alison Gulbis, Pharm.D., BCOP, is Clinical Pharmacy Specialist-Stem Cell Transplantation, Division of Pharmacy, University of Texas MD Anderson Cancer Center, Houston.AbstractPURPOSE: The case of an oncology patient who developed heparin-induced thrombocytopenia with thrombosis (HITT) and was treated with argatroban plus catheter-directed thrombolysis (CDT) with alteplase is presented.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists.Am J Health Syst Pharm.2014 May 1;71(9):711-6. doi: 10.2146/ajhp130132.
PURPOSE: The case of an oncology patient who developed heparin-induced thrombocytopenia with thrombosis (HITT) and was treated with argatroban plus catheter-directed thrombolysis (CDT) with alteplase is presented.SUMMARY: A 63-year-old Caucasian man with renal amyloidosis undergoing peripheral blood
PMID 24733133

Prognostic value of depressed midwall systolic function in cardiac light-chain amyloidosis.

Perlini S1, Salinaro F, Musca F, Mussinelli R, Boldrini M, Raimondi A, Milani P, Foli A, Cappelli F, Perfetto F, Palladini G, Rapezzi C, Merlini G.Author information 1aDepartment of Internal Medicine bAmyloidosis Research and Treatment Center and Department of Molecular Medicine, Fondazione IRCCS San Matteo, University of Pavia, Pavia cIntensive Cardiac Care Unit, Heart and Vessel Department dInternal Medicine Department, University of Florence, Florence eInstitute of Cardiology, S. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.AbstractBACKGROUND: Cardiac amyloidosis represents an archetypal form of restrictive heart disease, characterized by profound diastolic dysfunction. As ejection fraction is preserved until the late stage of the disease, the majority of patients do fulfill the definition of diastolic heart failure, that is, heart failure with preserved ejection fraction (HFpEF). In another clinical model of HFpEF, that is, pressure-overload hypertrophy, depressed midwall fractional shortening (mFS) has been shown to be a powerful prognostic factor.
Journal of hypertension.J Hypertens.2014 May;32(5):1121-31. doi: 10.1097/HJH.0000000000000120.
BACKGROUND: Cardiac amyloidosis represents an archetypal form of restrictive heart disease, characterized by profound diastolic dysfunction. As ejection fraction is preserved until the late stage of the disease, the majority of patients do fulfill the definition of diastolic heart failure, that is,
PMID 24509117

Pulmonary amyloidosis in a patient with Langerhans cell histiocytosis: diagnostic dilemma on 18F-FDG PET/CT.

Mukherjee A1, Dhull VS, Sharma P, Parida GK, Jain S, Pal L, Kumar R.Author information 1From the *Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi; and †Department of Pathology, Sanjay Gandhi Post Graduate Institute, Lucknow, India.AbstractAmyloidosis associated with Langerhans cell histiocytosis (LCH) is extremely rare. We here present the 18F-FDG PET/CT images of a 48-year-old male patient with multifocal skeletal involvement of LCH. In addition, he had a left lung upper lobe 18F-FDG avid mass that was misinterpreted as pulmonary involvement of LCH on PET/CT. Biopsy from the mass showed amyloidosis. Therefore, amyloidosis should be kept as a differential for 18F-FDG pulmonary avid nodule.
Clinical nuclear medicine.Clin Nucl Med.2014 Apr;39(4):e263-4. doi: 10.1097/RLU.0b013e3182a7556d.
Amyloidosis associated with Langerhans cell histiocytosis (LCH) is extremely rare. We here present the 18F-FDG PET/CT images of a 48-year-old male patient with multifocal skeletal involvement of LCH. In addition, he had a left lung upper lobe 18F-FDG avid mass that was misinterpreted as pulmonary in
PMID 24097004

金森斎修,倉堀純,竹中雅彦,松田良信,塚本吉胤
気管支学 : 日本気管支研究会雑誌 35(5), 530-536, 2013-09-25
背景.アミロイドーシスは,アミロイドと呼ばれる異常蛋白が組織に沈着しさまざまな症候を生じる代謝症候群である.全身性アミロイドーシスと限局性アミロイドーシスに分類され,肺に限局する限局性肺アミロイドーシスはまれとされる.症例. 78歳女性. 2009年76歳時に喀血にて紹介受診.両側肺野に石灰化を伴う複数の結節ないし腫瘤影を認めた. FDG-PETで一部の病変にFDGの集積を認めた.気管支鏡検査で気 …
NAID 110009661338

日野佑美,梶政洋,堀内翔,宮原尚文,小林零,末舛恵一
日本呼吸器外科学会雑誌 27(4), 456-459, 2013
症例は51歳，女性．呼吸困難感を自覚し胸部CTを施行したところ，両肺に多発する結節影及び嚢胞性病変を認め，精査目的に胸腔鏡下肺部分切除術を施行した．病理検査で結節はCongo red染色に陽性であり，肺アミロイドーシスによる結節と，その二次性変化としての嚢胞と診断した．特徴的な画像所見であり，また多発する肺結節・嚢胞性病変の鑑別診断として認知しておくべき疾患であると考えられた．
NAID 130003368778